ZA897349B - (-)-2-((2-(2-aminoethoxy)ethoxy)methyl)-4-(2,3-dichloro-phenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine,process for preparing it and pharmaceutical compositions containing it - Google Patents
(-)-2-((2-(2-aminoethoxy)ethoxy)methyl)-4-(2,3-dichloro-phenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine,process for preparing it and pharmaceutical compositions containing itInfo
- Publication number
- ZA897349B ZA897349B ZA897349A ZA897349A ZA897349B ZA 897349 B ZA897349 B ZA 897349B ZA 897349 A ZA897349 A ZA 897349A ZA 897349 A ZA897349 A ZA 897349A ZA 897349 B ZA897349 B ZA 897349B
- Authority
- ZA
- South Africa
- Prior art keywords
- methyl
- aminoethoxy
- methoxycarbonyl
- ethoxy
- dihydropyridine
- Prior art date
Links
- VLTBMBOHGZAWIT-UHFFFAOYSA-N 3-o-ethyl 5-o-methyl 2-[2-(2-aminoethoxy)ethoxymethyl]-4-(2,3-dichlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate Chemical compound CCOC(=O)C1=C(COCCOCCN)NC(C)=C(C(=O)OC)C1C1=CC=CC(Cl)=C1Cl VLTBMBOHGZAWIT-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- -1 (-)2{[2-(2-Aminoethoxy)ethoxy]methyl}-4-(2,3-dichlorophenyl)-3-etho xycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine compound Chemical class 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8908920A FR2649395B1 (fr) | 1989-07-04 | 1989-07-04 | Nouveau derive de la dihydro-1,4 pyridine denomme (-) i1(((amino-2 ethoxy)-2 ethoxy) methyli1) -2 (dichloro-2,3 phenyl)-4 ethoxycarbonyl-3 methoxycarbonyl-5 methyl-6 dihydro-1,4 pyridine, son procede de preparation et les compositions qui le contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA897349B true ZA897349B (en) | 1990-09-26 |
Family
ID=9383413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA897349A ZA897349B (en) | 1989-07-04 | 1989-09-27 | (-)-2-((2-(2-aminoethoxy)ethoxy)methyl)-4-(2,3-dichloro-phenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine,process for preparing it and pharmaceutical compositions containing it |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0406502B1 (da) |
| JP (1) | JPH0720934B2 (da) |
| AT (1) | ATE122340T1 (da) |
| AU (1) | AU619049B2 (da) |
| CA (1) | CA1327582C (da) |
| DE (1) | DE68922605T2 (da) |
| DK (1) | DK478989A (da) |
| ES (1) | ES2074472T3 (da) |
| FR (1) | FR2649395B1 (da) |
| IE (1) | IE67059B1 (da) |
| NZ (1) | NZ230854A (da) |
| OA (1) | OA09136A (da) |
| PT (1) | PT91869B (da) |
| ZA (1) | ZA897349B (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2652083B1 (fr) * | 1989-09-20 | 1992-01-24 | Ador Cie | Nouveau procede de separation d'isomeres optiques des derives de la dihydro-1,4 pyridine. |
| FR2686879B1 (fr) * | 1992-02-05 | 1994-03-18 | Adir Cie | Nouveaux composes de 1,4-dihydropyridine, leur procede de preparation et les compositions pharmaceutiques les contenant. |
| DE4444864A1 (de) * | 1994-12-16 | 1996-06-20 | Bayer Ag | Verwendung von 5-Acyl-1,4-dihydropyridinen |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK161312C (da) * | 1982-03-11 | 1991-12-09 | Pfizer | Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden |
| FR2602231B1 (fr) * | 1986-08-04 | 1988-10-28 | Adir | Nouveaux derives de la dihydro-1,4 pyridine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
-
1989
- 1989-07-04 FR FR8908920A patent/FR2649395B1/fr not_active Expired - Lifetime
- 1989-09-27 ZA ZA897349A patent/ZA897349B/xx unknown
- 1989-09-27 CA CA000613708A patent/CA1327582C/fr not_active Expired - Fee Related
- 1989-09-28 IE IE310389A patent/IE67059B1/en not_active IP Right Cessation
- 1989-09-28 DK DK478989A patent/DK478989A/da not_active Application Discontinuation
- 1989-09-29 AU AU42390/89A patent/AU619049B2/en not_active Ceased
- 1989-10-02 JP JP1257628A patent/JPH0720934B2/ja not_active Expired - Lifetime
- 1989-10-02 DE DE68922605T patent/DE68922605T2/de not_active Expired - Fee Related
- 1989-10-02 ES ES89402702T patent/ES2074472T3/es not_active Expired - Lifetime
- 1989-10-02 AT AT89402702T patent/ATE122340T1/de not_active IP Right Cessation
- 1989-10-02 NZ NZ230854A patent/NZ230854A/xx unknown
- 1989-10-02 EP EP89402702A patent/EP0406502B1/fr not_active Expired - Lifetime
- 1989-10-02 OA OA59656A patent/OA09136A/xx unknown
- 1989-10-02 PT PT91869A patent/PT91869B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ230854A (en) | 1991-02-26 |
| DE68922605T2 (de) | 1996-01-04 |
| AU619049B2 (en) | 1992-01-16 |
| OA09136A (fr) | 1991-10-31 |
| PT91869B (pt) | 1995-07-18 |
| PT91869A (pt) | 1991-03-20 |
| JPH0720934B2 (ja) | 1995-03-08 |
| DE68922605D1 (de) | 1995-06-14 |
| FR2649395B1 (fr) | 1992-11-06 |
| CA1327582C (fr) | 1994-03-08 |
| ES2074472T3 (es) | 1995-09-16 |
| JPH0344371A (ja) | 1991-02-26 |
| DK478989A (da) | 1991-01-05 |
| IE67059B1 (en) | 1996-02-21 |
| ATE122340T1 (de) | 1995-05-15 |
| IE893103A1 (en) | 1991-01-16 |
| DK478989D0 (da) | 1989-09-28 |
| EP0406502B1 (fr) | 1995-05-10 |
| EP0406502A1 (fr) | 1991-01-09 |
| AU4239089A (en) | 1991-01-10 |
| FR2649395A1 (fr) | 1991-01-11 |
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