ZA895387B - Novel s-adenosyl methionine decarboxylase inhibitors - Google Patents

Novel s-adenosyl methionine decarboxylase inhibitors

Info

Publication number
ZA895387B
ZA895387B ZA895387A ZA895387A ZA895387B ZA 895387 B ZA895387 B ZA 895387B ZA 895387 A ZA895387 A ZA 895387A ZA 895387 A ZA895387 A ZA 895387A ZA 895387 B ZA895387 B ZA 895387B
Authority
ZA
South Africa
Prior art keywords
novel
chem
decarboxylase inhibitors
adenosyl methionine
methionine decarboxylase
Prior art date
Application number
ZA895387A
Other languages
English (en)
Inventor
Patrick Casara
Casara Patrick
Charles Danzin
Danzin Charles
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA895387B publication Critical patent/ZA895387B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA895387A 1988-07-21 1989-07-14 Novel s-adenosyl methionine decarboxylase inhibitors ZA895387B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP88401896A EP0351475A1 (fr) 1988-07-21 1988-07-21 Inhibiteurs de S-adénosylméthionine-décarboxylase

Publications (1)

Publication Number Publication Date
ZA895387B true ZA895387B (en) 1990-04-25

Family

ID=8200409

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA895387A ZA895387B (en) 1988-07-21 1989-07-14 Novel s-adenosyl methionine decarboxylase inhibitors

Country Status (8)

Country Link
US (1) US5416076A (fr)
EP (1) EP0351475A1 (fr)
AT (1) ATE137759T1 (fr)
DE (1) DE68926418T2 (fr)
ES (1) ES2088903T3 (fr)
GR (1) GR3019893T3 (fr)
HU (1) HU204536B (fr)
ZA (1) ZA895387B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA916464B (en) * 1990-08-22 1992-05-27 Merrell Dow Pharma 5'-amine substituted adenosine analogs as immunosuppressants
US5308837A (en) * 1990-08-22 1994-05-03 Merrell Dow Pharmaceuticals Inc. 5'-amine substituted adenosine analogs as immunosuppressants
US5750496A (en) * 1996-08-12 1998-05-12 Utah State University Method of controlling cryptosporidium infectons using protease inhibitors
US5733889A (en) * 1996-10-29 1998-03-31 The Metrohealth System Treatment for cardiac arrhythmias
US6534651B2 (en) * 2000-04-06 2003-03-18 Inotek Pharmaceuticals Corp. 7-Substituted isoindolinone inhibitors of inflammation and reperfusion injury and methods of use thereof
US20030224970A1 (en) * 2002-05-17 2003-12-04 Sanjoy Mahanty Methods for the identification of inhibitors of S-adenosylmethionine decarboxylase as antibiotics
EP1834669A1 (fr) * 2006-03-15 2007-09-19 Heinrich-Pette-Institut Utilisation de composés hydrazones pour traiter les infections virales
WO2008157438A1 (fr) * 2007-06-15 2008-12-24 Genzyme Corporation Inhibiteurs de s-adénosyl-l-méthionine décarboxylase
EA201070054A1 (ru) * 2007-08-02 2010-10-29 Саузерн Рисерч Инститьют 5-замещённые аденозины, их получение и применение в качестве ингибиторов s-аденозилметиониндекарбоксилазы

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4134918A (en) * 1977-09-06 1979-01-16 Merrell Toraude Et Compagnie Alpha-halomethyl derivatives of amines
US4794174A (en) * 1987-02-10 1988-12-27 Southern Research Institute 5'deoxy-5'-substituted adenosines

Also Published As

Publication number Publication date
DE68926418D1 (de) 1996-06-13
US5416076A (en) 1995-05-16
HU204536B (en) 1992-01-28
HUT50354A (en) 1990-01-29
ATE137759T1 (de) 1996-05-15
ES2088903T3 (es) 1996-10-01
GR3019893T3 (en) 1996-08-31
EP0351475A1 (fr) 1990-01-24
DE68926418T2 (de) 1996-09-19

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