ZA895050B - Cyclic grf analogs - Google Patents

Cyclic grf analogs

Info

Publication number
ZA895050B
ZA895050B ZA895050A ZA895050A ZA895050B ZA 895050 B ZA895050 B ZA 895050B ZA 895050 A ZA895050 A ZA 895050A ZA 895050 A ZA895050 A ZA 895050A ZA 895050 B ZA895050 B ZA 895050B
Authority
ZA
South Africa
Prior art keywords
ala
arg
leu
gln
phe
Prior art date
Application number
ZA895050A
Other languages
English (en)
Inventor
Jean Edouard Frederic Rivier
Edouard Frederic Rivier Jean
Catherine Laure Rivier
Laure Rivier Catherine
Wylie Walker Vale Jr
Walker Vale Wylie Jr
Original Assignee
Salk Inst For Biological Studi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Inst For Biological Studi filed Critical Salk Inst For Biological Studi
Publication of ZA895050B publication Critical patent/ZA895050B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth-hormone releasing factors (GH-RF) (Somatoliberin)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
ZA895050A 1988-07-22 1989-07-03 Cyclic grf analogs ZA895050B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/223,277 US5043322A (en) 1988-07-22 1988-07-22 Cyclic GRF analogs

Publications (1)

Publication Number Publication Date
ZA895050B true ZA895050B (en) 1990-04-25

Family

ID=22835815

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA895050A ZA895050B (en) 1988-07-22 1989-07-03 Cyclic grf analogs

Country Status (13)

Country Link
US (1) US5043322A (xx)
EP (1) EP0352014B1 (xx)
JP (1) JP2739910B2 (xx)
KR (1) KR0138907B1 (xx)
AT (1) ATE103609T1 (xx)
DE (1) DE68914205T2 (xx)
DK (1) DK355889A (xx)
ES (1) ES2055792T3 (xx)
FI (1) FI91074C (xx)
IE (1) IE892378L (xx)
IL (1) IL90766A0 (xx)
NO (1) NO892970L (xx)
ZA (1) ZA895050B (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05507939A (ja) * 1991-04-09 1993-11-11 エフ・ホフマン―ラ　ロシユ　アーゲー 成長ホルモン放出因子の類似体
US5262519A (en) * 1991-05-15 1993-11-16 The Salk Institute For Biological Studies GRF analogs XI
US5371070A (en) * 1992-11-09 1994-12-06 The Salk Institute For Biological Studies Bicyclic GnRH antagonists and a method for regulating the secretion of gonadotropins
US6008058A (en) * 1993-06-18 1999-12-28 University Of Louisville Cyclic peptide mixtures via side chain or backbone attachment and solid phase synthesis
US5639598A (en) * 1994-05-19 1997-06-17 The Trustees Of The University Of Pennsylvania Method and kit for identification of antiviral agents capable of abrogating HIV Vpr-Rip-1 binding interactions
US5780220A (en) * 1994-05-19 1998-07-14 Trustees Of The University Of Pennsylvania Methods and compositions for inhibiting HIV replication
US5942489A (en) * 1996-05-03 1999-08-24 The Administrators Of The Tulane Educational Fund HGH-RH(1-29)NH2 analogues having antagonistic activity
EP1194548A4 (en) * 1999-06-23 2003-06-18 Wistar Inst NOVEL PYRRHOCORICIN-DERIVED PEPTIDES AND METHODS OF IMPLEMENTING THE SAME
US7015309B1 (en) 1999-06-23 2006-03-21 The Wistar Institute Of Anatomy And Biology Pyrrhocoricin-derived peptides, and methods of use thereof
PT2118123E (pt) 2007-01-31 2016-02-10 Harvard College Péptidos de p53 estabilizados e suas utilizações
KR20160061439A (ko) 2007-03-28 2016-05-31 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 스티칭된 폴리펩티드
CN108570097A (zh) 2010-08-13 2018-09-25 爱勒让治疗公司 拟肽大环化合物
AU2011348220B2 (en) 2010-12-22 2017-09-07 The Salk Institute For Biological Studies Cyclic CRF antagonist peptides
AU2012326026B2 (en) 2011-10-18 2017-04-13 Aileron Therapeutics, Inc. Peptidomimetic macrocyles
NZ627528A (en) 2012-02-15 2016-05-27 Aileron Therapeutics Inc Peptidomimetic macrocycles
US8987414B2 (en) 2012-02-15 2015-03-24 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
WO2014071241A1 (en) 2012-11-01 2014-05-08 Aileron Therapeutics, Inc. Disubstituted amino acids and methods of preparation and use thereof
CA2961258A1 (en) 2014-09-24 2016-03-31 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
JP2018516844A (ja) 2015-03-20 2018-06-28 エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ペプチド模倣大環状分子およびその使用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4595676A (en) * 1983-04-26 1986-06-17 The Salk Institute For Biological Studies Rat hypothalamic GRF
US4563352A (en) * 1982-10-04 1986-01-07 The Salk Institute For Biological Studies Human pancreatic GRF
US4518586A (en) * 1983-01-13 1985-05-21 The Salk Institute For Biological Studies GRF Analogs III
US4626523A (en) * 1983-09-13 1986-12-02 The Salk Institute For Biological Studies GRF analogs II
US4528190A (en) * 1983-10-25 1985-07-09 The Salk Institute For Biological Studies GRF Analogs IV
US4661472A (en) * 1985-05-09 1987-04-28 The Salk Institute For Biological Studies GnRH antagonists IX
US4734399A (en) * 1985-08-06 1988-03-29 Hoffmann-La Roche Inc. Growth hormone releasing factor analogs
US4689318A (en) * 1985-08-29 1987-08-25 The Salk Institute For Biological Studies GRF analogs
US4784987A (en) * 1987-01-13 1988-11-15 The Salk Institute For Biological Studies GRF analogs VI
IL84758A (en) * 1987-01-13 1992-03-29 Salk Inst For Biological Studi Peptides stimulating the release of pituitary growth hormone in fish and amphibians,and pharmaceutical compositions containing them
ES2054754T3 (es) * 1987-09-18 1994-08-16 Hoffmann La Roche Analogos ciclicos del grf.

Also Published As

Publication number Publication date
FI893532A0 (fi) 1989-07-21
IE892378L (en) 1990-01-22
JPH0269499A (ja) 1990-03-08
EP0352014B1 (en) 1994-03-30
NO892970L (no) 1990-01-23
DE68914205T2 (de) 1994-07-07
KR0138907B1 (ko) 1998-04-30
IL90766A0 (en) 1990-01-18
EP0352014A2 (en) 1990-01-24
US5043322A (en) 1991-08-27
DK355889A (da) 1990-01-23
DE68914205D1 (de) 1994-05-05
JP2739910B2 (ja) 1998-04-15
DK355889D0 (da) 1989-07-18
FI893532A (fi) 1990-01-23
NO892970D0 (no) 1989-07-20
ATE103609T1 (de) 1994-04-15
EP0352014A3 (en) 1991-07-03
FI91074C (fi) 1994-05-10
FI91074B (fi) 1994-01-31
ES2055792T3 (es) 1994-09-01
KR910002900A (ko) 1991-02-26

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