ZA892622B - 3-substituted-2-oxindole-1-carboxamides for suppressing t-cell function - Google Patents

3-substituted-2-oxindole-1-carboxamides for suppressing t-cell function

Info

Publication number
ZA892622B
ZA892622B ZA892622A ZA892622A ZA892622B ZA 892622 B ZA892622 B ZA 892622B ZA 892622 A ZA892622 A ZA 892622A ZA 892622 A ZA892622 A ZA 892622A ZA 892622 B ZA892622 B ZA 892622B
Authority
ZA
South Africa
Prior art keywords
cell function
oxindole
carboxamides
substituted
suppressing
Prior art date
Application number
ZA892622A
Other languages
English (en)
Inventor
Henry James Showell
James Showell Henry
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA892622B publication Critical patent/ZA892622B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
ZA892622A 1988-04-13 1989-04-11 3-substituted-2-oxindole-1-carboxamides for suppressing t-cell function ZA892622B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/181,142 US4853409A (en) 1988-04-13 1988-04-13 3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function

Publications (1)

Publication Number Publication Date
ZA892622B true ZA892622B (en) 1990-11-28

Family

ID=22663072

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA892622A ZA892622B (en) 1988-04-13 1989-04-11 3-substituted-2-oxindole-1-carboxamides for suppressing t-cell function

Country Status (17)

Country Link
US (1) US4853409A (fr)
EP (1) EP0337628B1 (fr)
JP (1) JPH01311022A (fr)
KR (1) KR920002328B1 (fr)
AT (1) ATE89725T1 (fr)
AU (1) AU601326B2 (fr)
CA (1) CA1324762C (fr)
DE (1) DE68906707T2 (fr)
DK (1) DK174289A (fr)
HU (1) HU204996B (fr)
IE (1) IE62751B1 (fr)
IL (1) IL89872A (fr)
MY (1) MY103872A (fr)
NZ (1) NZ228712A (fr)
PH (1) PH25857A (fr)
PT (1) PT90249B (fr)
ZA (1) ZA892622B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5006547A (en) * 1990-03-19 1991-04-09 Pfizer Inc. Tenidap as an inhibitor of the release of elastase by neutrophils
US5008283A (en) * 1990-03-19 1991-04-16 Pfizer Inc. Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase
US5122534A (en) * 1991-02-08 1992-06-16 Pfizer Inc. Use of tenidap to reduce total serum cholesterol, ldl cholesterol and triglycerides
DE4111306C2 (de) * 1991-04-08 1994-06-01 Mack Chem Pharm Pharmazeutische Zubereitungen, die ein 2-Oxindol-l-carboxamid-derivat enthalten und zur Injektion bestimmt sind
DE4111305C2 (de) * 1991-04-08 1994-12-01 Mack Chem Pharm Pharmazeutische Zubereitung zur rektalen Applikation, die ein 2-Oxindol-l-carboxamid-derivat enthält
DK0680321T3 (da) * 1993-01-22 1999-06-14 Pfizer Lysinsalt af 6-chlor-5-fluor-3-(2-thenoyl)-2-oxindol-1-carboxamid
US5298522A (en) * 1993-01-22 1994-03-29 Pfizer Inc. 6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide as an analgesic and anti-inflammatory agent while maintaining a normal urine protein/creatinine ratio
US5545656A (en) * 1995-04-05 1996-08-13 Pfizer Inc. 2-Oxidole-1-carboxamide pharmaceutical agents for the treatment of alzheimer's disease
SK281254B6 (sk) * 1995-07-13 2001-01-18 Smithkline Beecham Corporation Použitie@kán-2-propánamínu, farmaceutický prostriedok s jeho obsahom a jeho použitie
AU7503496A (en) * 1995-12-19 1997-07-14 Pfizer Inc. Stable, long acting salts of indole derivatives for the treatment of joint diseases
EP0826685A1 (fr) * 1996-08-21 1998-03-04 Pfizer Inc. Sels de carboxamides stables à effet prolongé destinés au traitement des maladies articulaires
WO2006105796A1 (fr) * 2005-04-08 2006-10-12 Leo Pharma A/S Nouveaux dérivés d'indolinone
EP2886541A1 (fr) * 2013-12-19 2015-06-24 Sanofi Dérivés d'oxindole, leur préparation et leur utilisation thérapeutique pour traiter les troubles liés à l'AMPK

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
DE3413572A1 (de) * 1984-04-11 1985-10-24 Hoechst Ag, 6230 Frankfurt Oxindol-verbindungen zur behandlung der epilepsie
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
AU6898287A (en) * 1986-01-30 1987-08-25 University Of Utah, The Treatment of bone loss
US5036099A (en) * 1987-02-02 1991-07-30 Pfizer Inc. Anhydrous, crystalline sodium salt of 5-chloro-3-(2-thenoyl)-2-oxindole-1-carboxamide

Also Published As

Publication number Publication date
DE68906707D1 (de) 1993-07-01
IL89872A (en) 1994-06-24
MY103872A (en) 1993-09-30
HUT52376A (en) 1990-07-28
IL89872A0 (en) 1989-12-15
PT90249A (pt) 1989-11-10
JPH01311022A (ja) 1989-12-15
EP0337628B1 (fr) 1993-05-26
KR890015740A (ko) 1989-11-25
AU3271289A (en) 1989-10-19
AU601326B2 (en) 1990-09-06
KR920002328B1 (ko) 1992-03-21
HU204996B (en) 1992-03-30
PT90249B (pt) 1994-06-30
DE68906707T2 (de) 1993-09-16
ATE89725T1 (de) 1993-06-15
IE62751B1 (en) 1995-02-22
EP0337628A2 (fr) 1989-10-18
EP0337628A3 (fr) 1991-01-02
US4853409A (en) 1989-08-01
DK174289D0 (da) 1989-04-12
CA1324762C (fr) 1993-11-30
PH25857A (en) 1991-12-02
NZ228712A (en) 1997-02-24
IE891171L (en) 1989-10-13
DK174289A (da) 1989-10-16

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