ZA892312B - 7-(imidazol-1-yl)-1,4-dihydro-4-oxo-6,8-difluoro-1-cyclo-propylquinoline-3-carboxylic acid derivatives their preparation and their application as drugs - Google Patents
7-(imidazol-1-yl)-1,4-dihydro-4-oxo-6,8-difluoro-1-cyclo-propylquinoline-3-carboxylic acid derivatives their preparation and their application as drugsInfo
- Publication number
- ZA892312B ZA892312B ZA892312A ZA892312A ZA892312B ZA 892312 B ZA892312 B ZA 892312B ZA 892312 A ZA892312 A ZA 892312A ZA 892312 A ZA892312 A ZA 892312A ZA 892312 B ZA892312 B ZA 892312B
- Authority
- ZA
- South Africa
- Prior art keywords
- propylquinoline
- imidazol
- cyclo
- difluoro
- dihydro
- Prior art date
Links
- DYSJRVICBNGFHB-UHFFFAOYSA-N 1-cyclopropyl-6,8-difluoro-7-imidazol-1-yl-4-oxoquinoline-3-carboxylic acid Chemical class C12=C(F)C(N3C=NC=C3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 DYSJRVICBNGFHB-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- -1 alkyl radical Chemical class 0.000 abstract 2
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 150000005840 aryl radicals Chemical class 0.000 abstract 1
- 150000002391 heterocyclic compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8804289A FR2629456B1 (fr) | 1988-03-31 | 1988-03-31 | Derives des acides 7-(1-imidazolyl),1,4-dihydro-4-oxo-6,8-difluoro-1-cyclopropyl-3-quinoleincarboxylique, leur preparation et leur application en tant que medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA892312B true ZA892312B (en) | 1989-12-27 |
Family
ID=9364848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA892312A ZA892312B (en) | 1988-03-31 | 1989-03-29 | 7-(imidazol-1-yl)-1,4-dihydro-4-oxo-6,8-difluoro-1-cyclo-propylquinoline-3-carboxylic acid derivatives their preparation and their application as drugs |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5098913A (es) |
| EP (1) | EP0340055B1 (es) |
| AT (1) | ATE86620T1 (es) |
| AU (1) | AU618794B2 (es) |
| DE (1) | DE68905222T2 (es) |
| ES (1) | ES2010471A6 (es) |
| FR (1) | FR2629456B1 (es) |
| GR (1) | GR3007320T3 (es) |
| NZ (1) | NZ228515A (es) |
| ZA (1) | ZA892312B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2002864C (en) * | 1988-11-29 | 1999-11-16 | Eddy J. E. Freyne | (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59128383A (ja) * | 1982-12-29 | 1984-07-24 | Kanebo Ltd | 新規キノリンカルボン酸誘導体および該化合物を有効成分とする抗菌剤 |
| FR2574404B1 (fr) * | 1984-12-12 | 1987-04-24 | Provesan Sa | Derives 1-substitues de l'acide 6-fluoro-7-(pyrrol-1-yl)-1,4-dihydro-4-oxoquinoleine-3-carboxylique, leur preparation et leur application en tant que medicaments |
| DE3519286A1 (de) * | 1985-05-30 | 1986-12-04 | Bayer Ag, 5090 Leverkusen | 7-azolyl-1-cyclopropyl-1,4-dihydro-4-oxo-3- chinolincarbonsaeuren und -1,8-naphthyridin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
-
1988
- 1988-03-31 FR FR8804289A patent/FR2629456B1/fr not_active Expired - Lifetime
-
1989
- 1989-03-29 ZA ZA892312A patent/ZA892312B/xx unknown
- 1989-03-29 DE DE8989400873T patent/DE68905222T2/de not_active Expired - Fee Related
- 1989-03-29 NZ NZ228515A patent/NZ228515A/en unknown
- 1989-03-29 ES ES8901094A patent/ES2010471A6/es not_active Expired
- 1989-03-29 AT AT89400873T patent/ATE86620T1/de not_active IP Right Cessation
- 1989-03-29 EP EP89400873A patent/EP0340055B1/fr not_active Expired - Lifetime
- 1989-03-31 AU AU32263/89A patent/AU618794B2/en not_active Ceased
-
1991
- 1991-02-08 US US07/653,856 patent/US5098913A/en not_active Expired - Fee Related
-
1993
- 1993-03-11 GR GR930400396T patent/GR3007320T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE68905222D1 (de) | 1993-04-15 |
| ES2010471A6 (es) | 1989-11-01 |
| FR2629456A1 (fr) | 1989-10-06 |
| AU618794B2 (en) | 1992-01-09 |
| DE68905222T2 (de) | 1993-06-17 |
| FR2629456B1 (fr) | 1991-07-05 |
| US5098913A (en) | 1992-03-24 |
| NZ228515A (en) | 1990-10-26 |
| EP0340055A1 (fr) | 1989-11-02 |
| AU3226389A (en) | 1989-10-05 |
| GR3007320T3 (es) | 1993-07-30 |
| ATE86620T1 (de) | 1993-03-15 |
| EP0340055B1 (fr) | 1993-03-10 |
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