ZA88895B - Pyridine-2,4-and-2,5-dicarboxylic acid derivatives,a process for the preparation,the use thereof,and medicaments based on these compounds - Google Patents

Pyridine-2,4-and-2,5-dicarboxylic acid derivatives,a process for the preparation,the use thereof,and medicaments based on these compounds

Info

Publication number
ZA88895B
ZA88895B ZA880895A ZA88895A ZA88895B ZA 88895 B ZA88895 B ZA 88895B ZA 880895 A ZA880895 A ZA 880895A ZA 88895 A ZA88895 A ZA 88895A ZA 88895 B ZA88895 B ZA 88895B
Authority
ZA
South Africa
Prior art keywords
pyridine
compounds
preparation
dicarboxylic acid
acid derivatives
Prior art date
Application number
ZA880895A
Other languages
English (en)
Inventor
Brocks Dietrich
Burghard Harald
Guenzler Volkmar
Hanauske-Abel Hartmut
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of ZA88895B publication Critical patent/ZA88895B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Treatment And Processing Of Natural Fur Or Leather (AREA)
  • Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Peptides Or Proteins (AREA)
ZA880895A 1987-02-10 1988-02-09 Pyridine-2,4-and-2,5-dicarboxylic acid derivatives,a process for the preparation,the use thereof,and medicaments based on these compounds ZA88895B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873703962 DE3703962A1 (de) 1987-02-10 1987-02-10 Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen

Publications (1)

Publication Number Publication Date
ZA88895B true ZA88895B (en) 1988-08-08

Family

ID=6320592

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA880895A ZA88895B (en) 1987-02-10 1988-02-09 Pyridine-2,4-and-2,5-dicarboxylic acid derivatives,a process for the preparation,the use thereof,and medicaments based on these compounds

Country Status (20)

Country Link
US (1) US4968670A (xx)
EP (1) EP0278454B1 (xx)
JP (1) JPS63216871A (xx)
KR (1) KR960004861B1 (xx)
AT (1) ATE85048T1 (xx)
AU (1) AU604293B2 (xx)
CA (1) CA1315471C (xx)
DE (2) DE3703962A1 (xx)
DK (1) DK168008B1 (xx)
ES (1) ES2046218T3 (xx)
FI (1) FI90767C (xx)
GR (1) GR3007607T3 (xx)
HU (1) HU199801B (xx)
IE (1) IE62353B1 (xx)
IL (1) IL85360A0 (xx)
NO (1) NO174852C (xx)
NZ (1) NZ223432A (xx)
PH (1) PH24512A (xx)
PT (1) PT86735B (xx)
ZA (1) ZA88895B (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5519038A (en) * 1989-07-20 1996-05-21 Hoechst Aktiengesellschaft N,N'-bis(alkoxyalkyl)-pyridine-2,4-dicarboxylic acid diamines

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3707429A1 (de) * 1987-03-07 1988-09-15 Hoechst Ag Substituierte pyridin-2,4-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE3924093A1 (de) * 1989-07-20 1991-02-07 Hoechst Ag N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
DE3938805A1 (de) * 1989-11-23 1991-05-29 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
DE4020570A1 (de) 1990-06-28 1992-01-02 Hoechst Ag 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung
DE4031000A1 (de) * 1990-10-01 1992-04-09 Hoechst Ag 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
YU9492A (sh) * 1991-02-05 1995-03-27 Hoechst Ag. 2,4- i 2,5-bis-tetrazolilni piridini i postupak za njihovo dobijanje
EP0548883A1 (de) * 1991-12-24 1993-06-30 Hoechst Aktiengesellschaft Substituierte Pyridin-N-oxide, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
TW352384B (en) * 1992-03-24 1999-02-11 Hoechst Ag Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals
DE4233124A1 (de) * 1992-10-02 1994-04-07 Hoechst Ag Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO1999021860A1 (en) * 1997-10-24 1999-05-06 Fibrogen, Inc. Phenanthroline derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3432094A1 (de) * 1984-08-31 1986-03-06 Hoechst Ag, 6230 Frankfurt Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase
EP0353668B1 (de) * 1988-08-04 1994-10-19 Hoechst Aktiengesellschaft Verbessertes Verfahren zur Herstellung von N,N-Bis(alkoxyalkyl)-pyridin -2,4-dicarbonsäurediamiden

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5519038A (en) * 1989-07-20 1996-05-21 Hoechst Aktiengesellschaft N,N'-bis(alkoxyalkyl)-pyridine-2,4-dicarboxylic acid diamines

Also Published As

Publication number Publication date
DE3703962A1 (de) 1988-08-18
NO880557L (no) 1988-08-11
AU1145188A (en) 1988-08-11
CA1315471C (en) 1993-03-30
NO174852C (no) 1994-07-20
FI90767C (fi) 1994-03-25
US4968670A (en) 1990-11-06
NO174852B (no) 1994-04-11
EP0278454A2 (de) 1988-08-17
KR880009934A (ko) 1988-10-05
DK66188A (da) 1988-08-11
DK168008B1 (da) 1994-01-17
DK66188D0 (da) 1988-02-09
ES2046218T3 (es) 1994-02-01
IE880351L (en) 1988-08-10
NZ223432A (en) 1990-04-26
HU199801B (en) 1990-03-28
HUT47251A (en) 1989-02-28
KR960004861B1 (en) 1996-04-16
PT86735B (pt) 1992-05-29
PT86735A (pt) 1988-03-01
ATE85048T1 (de) 1993-02-15
EP0278454A3 (en) 1989-10-18
AU604293B2 (en) 1990-12-13
FI880555A (fi) 1988-08-11
IE62353B1 (en) 1995-01-25
EP0278454B1 (de) 1993-01-27
IL85360A0 (en) 1988-07-31
NO880557D0 (no) 1988-02-09
JPS63216871A (ja) 1988-09-09
GR3007607T3 (xx) 1993-08-31
DE3877778D1 (de) 1993-03-11
FI90767B (fi) 1993-12-15
FI880555A0 (fi) 1988-02-08
PH24512A (en) 1990-07-18

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