IL85360A0 - Pyridine-2-4-and 2,5-dicarboxylic acid derivatives,a process for their preparation and pharmaceutical compositions containing same - Google Patents
Pyridine-2-4-and 2,5-dicarboxylic acid derivatives,a process for their preparation and pharmaceutical compositions containing sameInfo
- Publication number
- IL85360A0 IL85360A0 IL85360A IL8536088A IL85360A0 IL 85360 A0 IL85360 A0 IL 85360A0 IL 85360 A IL85360 A IL 85360A IL 8536088 A IL8536088 A IL 8536088A IL 85360 A0 IL85360 A0 IL 85360A0
- Authority
- IL
- Israel
- Prior art keywords
- pyridine
- preparation
- dicarboxylic acid
- acid derivatives
- pharmaceutical compositions
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Treatment And Processing Of Natural Fur Or Leather (AREA)
- Bidet-Like Cleaning Device And Other Flush Toilet Accessories (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873703962 DE3703962A1 (de) | 1987-02-10 | 1987-02-10 | Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL85360A0 true IL85360A0 (en) | 1988-07-31 |
Family
ID=6320592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL85360A IL85360A0 (en) | 1987-02-10 | 1988-02-08 | Pyridine-2-4-and 2,5-dicarboxylic acid derivatives,a process for their preparation and pharmaceutical compositions containing same |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4968670A (xx) |
| EP (1) | EP0278454B1 (xx) |
| JP (1) | JPS63216871A (xx) |
| KR (1) | KR960004861B1 (xx) |
| AT (1) | ATE85048T1 (xx) |
| AU (1) | AU604293B2 (xx) |
| CA (1) | CA1315471C (xx) |
| DE (2) | DE3703962A1 (xx) |
| DK (1) | DK168008B1 (xx) |
| ES (1) | ES2046218T3 (xx) |
| FI (1) | FI90767C (xx) |
| GR (1) | GR3007607T3 (xx) |
| HU (1) | HU199801B (xx) |
| IE (1) | IE62353B1 (xx) |
| IL (1) | IL85360A0 (xx) |
| NO (1) | NO174852C (xx) |
| NZ (1) | NZ223432A (xx) |
| PH (1) | PH24512A (xx) |
| PT (1) | PT86735B (xx) |
| ZA (1) | ZA88895B (xx) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3707429A1 (de) * | 1987-03-07 | 1988-09-15 | Hoechst Ag | Substituierte pyridin-2,4-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
| DE3924093A1 (de) * | 1989-07-20 | 1991-02-07 | Hoechst Ag | N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung |
| US5425289A (en) * | 1993-10-21 | 1995-06-20 | Snap-On Incorporated | Bung tool |
| DE3938805A1 (de) * | 1989-11-23 | 1991-05-29 | Hoechst Ag | Pyridin-2,4- und 2,5-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung |
| DE4020570A1 (de) | 1990-06-28 | 1992-01-02 | Hoechst Ag | 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung |
| DE4031000A1 (de) * | 1990-10-01 | 1992-04-09 | Hoechst Ag | 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel |
| YU9492A (sh) * | 1991-02-05 | 1995-03-27 | Hoechst Ag. | 2,4- i 2,5-bis-tetrazolilni piridini i postupak za njihovo dobijanje |
| EP0548883A1 (de) * | 1991-12-24 | 1993-06-30 | Hoechst Aktiengesellschaft | Substituierte Pyridin-N-oxide, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
| TW352384B (en) * | 1992-03-24 | 1999-02-11 | Hoechst Ag | Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals |
| DE4233124A1 (de) * | 1992-10-02 | 1994-04-07 | Hoechst Ag | Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| AU754607B2 (en) * | 1997-10-24 | 2002-11-21 | Fibrogen, Inc. | Phenanthroline derivatives |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3432094A1 (de) * | 1984-08-31 | 1986-03-06 | Hoechst Ag, 6230 Frankfurt | Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase |
| ATE113036T1 (de) * | 1988-08-04 | 1994-11-15 | Hoechst Ag | Verbessertes verfahren zur herstellung von n,n- bis(alkoxyalkyl)-pyridin -2,4- dicarbonsäurediamiden. |
-
1987
- 1987-02-10 DE DE19873703962 patent/DE3703962A1/de not_active Withdrawn
-
1988
- 1988-02-08 ES ES198888101793T patent/ES2046218T3/es not_active Expired - Lifetime
- 1988-02-08 EP EP88101793A patent/EP0278454B1/de not_active Expired - Lifetime
- 1988-02-08 FI FI880555A patent/FI90767C/fi not_active IP Right Cessation
- 1988-02-08 NZ NZ223432A patent/NZ223432A/en unknown
- 1988-02-08 AT AT88101793T patent/ATE85048T1/de not_active IP Right Cessation
- 1988-02-08 PH PH36468A patent/PH24512A/en unknown
- 1988-02-08 IL IL85360A patent/IL85360A0/xx not_active IP Right Cessation
- 1988-02-08 DE DE8888101793T patent/DE3877778D1/de not_active Expired - Fee Related
- 1988-02-08 US US07/153,440 patent/US4968670A/en not_active Expired - Fee Related
- 1988-02-09 CA CA000558495A patent/CA1315471C/en not_active Expired - Fee Related
- 1988-02-09 NO NO880557A patent/NO174852C/no unknown
- 1988-02-09 DK DK066188A patent/DK168008B1/da not_active IP Right Cessation
- 1988-02-09 AU AU11451/88A patent/AU604293B2/en not_active Ceased
- 1988-02-09 IE IE35188A patent/IE62353B1/en not_active IP Right Cessation
- 1988-02-09 JP JP63026722A patent/JPS63216871A/ja active Pending
- 1988-02-09 PT PT86735A patent/PT86735B/pt not_active IP Right Cessation
- 1988-02-09 KR KR88001197A patent/KR960004861B1/ko active IP Right Grant
- 1988-02-09 ZA ZA880895A patent/ZA88895B/xx unknown
- 1988-02-10 HU HU88611A patent/HU199801B/hu not_active IP Right Cessation
-
1993
- 1993-04-09 GR GR930400360T patent/GR3007607T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT86735B (pt) | 1992-05-29 |
| FI90767C (fi) | 1994-03-25 |
| FI90767B (fi) | 1993-12-15 |
| DE3877778D1 (de) | 1993-03-11 |
| CA1315471C (en) | 1993-03-30 |
| IE62353B1 (en) | 1995-01-25 |
| KR880009934A (ko) | 1988-10-05 |
| HU199801B (en) | 1990-03-28 |
| NO174852B (no) | 1994-04-11 |
| US4968670A (en) | 1990-11-06 |
| NO174852C (no) | 1994-07-20 |
| EP0278454A2 (de) | 1988-08-17 |
| GR3007607T3 (xx) | 1993-08-31 |
| PT86735A (pt) | 1988-03-01 |
| DK66188A (da) | 1988-08-11 |
| ZA88895B (en) | 1988-08-08 |
| PH24512A (en) | 1990-07-18 |
| FI880555A (fi) | 1988-08-11 |
| AU604293B2 (en) | 1990-12-13 |
| NZ223432A (en) | 1990-04-26 |
| DK168008B1 (da) | 1994-01-17 |
| AU1145188A (en) | 1988-08-11 |
| FI880555A0 (fi) | 1988-02-08 |
| DE3703962A1 (de) | 1988-08-18 |
| ES2046218T3 (es) | 1994-02-01 |
| EP0278454A3 (en) | 1989-10-18 |
| KR960004861B1 (en) | 1996-04-16 |
| EP0278454B1 (de) | 1993-01-27 |
| DK66188D0 (da) | 1988-02-09 |
| JPS63216871A (ja) | 1988-09-09 |
| HUT47251A (en) | 1989-02-28 |
| NO880557D0 (no) | 1988-02-09 |
| NO880557L (no) | 1988-08-11 |
| IE880351L (en) | 1988-08-10 |
| ATE85048T1 (de) | 1993-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |