ZA88852B - Use of human blood coagulation factor xiii for the treatment of ulcerative colitis - Google Patents

Use of human blood coagulation factor xiii for the treatment of ulcerative colitis

Info

Publication number
ZA88852B
ZA88852B ZA88852A ZA88852A ZA88852B ZA 88852 B ZA88852 B ZA 88852B ZA 88852 A ZA88852 A ZA 88852A ZA 88852 A ZA88852 A ZA 88852A ZA 88852 B ZA88852 B ZA 88852B
Authority
ZA
South Africa
Prior art keywords
treatment
factor xiii
ulcerative colitis
blood coagulation
human blood
Prior art date
Application number
ZA88852A
Other languages
English (en)
Inventor
Mikio Urabe
Urabe Mikio
Satoshi Tanaka
Tanaka Satoshi
Kenichiro Tsumura
Tsumura Kenichiro
Original Assignee
Hoechst Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12192122&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA88852(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoechst Japan filed Critical Hoechst Japan
Publication of ZA88852B publication Critical patent/ZA88852B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
ZA88852A 1987-02-09 1988-02-08 Use of human blood coagulation factor xiii for the treatment of ulcerative colitis ZA88852B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62026387A JPS63196520A (ja) 1987-02-09 1987-02-09 潰瘍性大腸炎治療剤

Publications (1)

Publication Number Publication Date
ZA88852B true ZA88852B (en) 1988-11-30

Family

ID=12192122

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA88852A ZA88852B (en) 1987-02-09 1988-02-08 Use of human blood coagulation factor xiii for the treatment of ulcerative colitis

Country Status (16)

Country Link
US (1) US5378687A (el)
EP (1) EP0278416B1 (el)
JP (1) JPS63196520A (el)
KR (1) KR960014789B1 (el)
AT (1) ATE83665T1 (el)
AU (1) AU615428B2 (el)
CA (1) CA1322161C (el)
DE (1) DE3876817T2 (el)
DK (1) DK63488A (el)
ES (1) ES2052614T3 (el)
GR (1) GR3007331T3 (el)
HU (1) HU200277B (el)
IE (1) IE61713B1 (el)
IL (1) IL85346A (el)
PT (1) PT86721B (el)
ZA (1) ZA88852B (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3829524A1 (de) * 1988-08-31 1990-03-01 Behringwerke Ag Verwendung von transglutaminasen als immunsuppressiva
US5612456A (en) * 1988-11-14 1997-03-18 Zymogenetics, Inc. Factor XIII compositions
JPH03240738A (ja) * 1990-02-20 1991-10-28 Hoechst Japan Ltd 糖尿病性壊疽治療剤
AU3428493A (en) * 1991-12-31 1993-07-28 Zymogenetics Inc. Novel human transglutaminases
ATE171071T1 (de) * 1991-12-31 1998-10-15 Zymogenetics Inc Verfahren und zusammensetzungen zur verminderung von blutverlust
CA2463530A1 (en) 2001-10-09 2003-05-08 Zymogenetics, Inc. Method for inhibiting the formation of seromas using factor xiii
US20060104946A1 (en) * 2002-08-23 2006-05-18 Zymogenetics, Inc. Method for treating inflammatory bowel disease
JP5086093B2 (ja) 2004-11-23 2012-11-28 ジモジェネティクス、インコーポレイテッド 組換え型ヒトｘｉｉｉ因子の精製
US20140286927A1 (en) * 2012-06-19 2014-09-25 Peter Edward Smith Method for the treatment of ulcerative colitis in patients refractory to steroid therapy using leached ligand fibrin stabilizing composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6029687B2 (ja) * 1978-11-07 1985-07-12 株式会社ミドリ十字 ヒト胎盤由来血液凝固第１０３因子の濃縮液の製造方法

Also Published As

Publication number Publication date
ATE83665T1 (de) 1993-01-15
KR960014789B1 (en) 1996-10-19
EP0278416A2 (en) 1988-08-17
EP0278416B1 (en) 1992-12-23
US5378687A (en) 1995-01-03
AU1138288A (en) 1988-08-11
DK63488D0 (da) 1988-02-08
IL85346A (en) 1992-07-15
KR880009661A (ko) 1988-10-04
IE880334L (en) 1988-08-09
IE61713B1 (en) 1994-11-30
AU615428B2 (en) 1991-10-03
CA1322161C (en) 1993-09-14
PT86721B (pt) 1992-05-29
JPH0437049B2 (el) 1992-06-18
HU200277B (en) 1990-05-28
PT86721A (pt) 1988-03-01
IL85346A0 (en) 1988-07-31
HUT47221A (en) 1989-02-28
DE3876817D1 (de) 1993-02-04
DE3876817T2 (de) 1993-05-19
ES2052614T3 (es) 1994-07-16
JPS63196520A (ja) 1988-08-15
EP0278416A3 (en) 1990-07-11
DK63488A (da) 1988-08-10
GR3007331T3 (el) 1993-07-30

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