ZA885481B - (1r,5s,6s)-2-substituted thio-6-((r)-1-hydroxyethyl)-1-methyl-carbapenem-3-carboxylic acid - Google Patents
(1r,5s,6s)-2-substituted thio-6-((r)-1-hydroxyethyl)-1-methyl-carbapenem-3-carboxylic acidInfo
- Publication number
- ZA885481B ZA885481B ZA885481A ZA885481A ZA885481B ZA 885481 B ZA885481 B ZA 885481B ZA 885481 A ZA885481 A ZA 885481A ZA 885481 A ZA885481 A ZA 885481A ZA 885481 B ZA885481 B ZA 885481B
- Authority
- ZA
- South Africa
- Prior art keywords
- methyl
- carbapenem
- hydroxyethyl
- carboxylic acid
- substituted thio
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12955587A | 1987-12-07 | 1987-12-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA885481B true ZA885481B (en) | 1989-04-26 |
Family
ID=22440562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA885481A ZA885481B (en) | 1987-12-07 | 1988-07-27 | (1r,5s,6s)-2-substituted thio-6-((r)-1-hydroxyethyl)-1-methyl-carbapenem-3-carboxylic acid |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0326640B1 (da) |
| KR (1) | KR890009930A (da) |
| AT (1) | ATE88706T1 (da) |
| AU (1) | AU604949B2 (da) |
| DE (1) | DE3880660T2 (da) |
| DK (1) | DK168047B1 (da) |
| ES (1) | ES2053638T3 (da) |
| FI (1) | FI883505A (da) |
| IL (1) | IL87226A (da) |
| NO (1) | NO883297L (da) |
| ZA (1) | ZA885481B (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW264475B (da) * | 1991-09-20 | 1995-12-01 | Takeda Pharm Industry Co Ltd | |
| PT2326648E (pt) * | 2008-07-30 | 2012-10-31 | Ranbaxy Lab Ltd | Processo de preparação de compostos de carbapenem |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK153486C (da) * | 1978-07-03 | 1988-11-28 | Merck & Co Inc | Analogifremgangsmaade til fremstilling af krystallinsk n-formimidoyl-thienamycin-monohydrat |
| US4644061A (en) * | 1982-09-28 | 1987-02-17 | Bristol-Myers Company | Carbapenem antibiotics |
| CA1269978A (en) * | 1982-09-28 | 1990-06-05 | Choung U. Kim | Carbapenem antibiotics |
| US4713451A (en) * | 1984-04-09 | 1987-12-15 | Merck & Co., Inc. | Crystalline dimethyliminothienamycin |
| CA1273012A (en) * | 1984-07-02 | 1990-08-21 | Burton G. Christensen | 1-methylcarbapenems having an externally alkylated mono- of bicyclic 2-quarternary heteroarylalkylthio substituent |
-
1988
- 1988-07-22 DK DK411488A patent/DK168047B1/da not_active IP Right Cessation
- 1988-07-25 NO NO88883297A patent/NO883297L/no unknown
- 1988-07-25 FI FI883505A patent/FI883505A/fi not_active Application Discontinuation
- 1988-07-26 IL IL87226A patent/IL87226A/xx not_active IP Right Cessation
- 1988-07-27 ES ES88112142T patent/ES2053638T3/es not_active Expired - Lifetime
- 1988-07-27 DE DE8888112142T patent/DE3880660T2/de not_active Expired - Fee Related
- 1988-07-27 ZA ZA885481A patent/ZA885481B/xx unknown
- 1988-07-27 EP EP88112142A patent/EP0326640B1/en not_active Expired - Lifetime
- 1988-07-27 AT AT88112142T patent/ATE88706T1/de not_active IP Right Cessation
- 1988-07-29 KR KR1019880009645A patent/KR890009930A/ko not_active Application Discontinuation
- 1988-08-01 AU AU20257/88A patent/AU604949B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE3880660D1 (en) | 1993-06-03 |
| EP0326640A1 (en) | 1989-08-09 |
| FI883505A0 (fi) | 1988-07-25 |
| DE3880660T2 (de) | 1993-09-23 |
| FI883505A (fi) | 1989-06-08 |
| IL87226A0 (en) | 1988-12-30 |
| AU604949B2 (en) | 1991-01-03 |
| ES2053638T3 (es) | 1994-08-01 |
| ATE88706T1 (de) | 1993-05-15 |
| DK411488A (da) | 1989-06-08 |
| DK411488D0 (da) | 1988-07-22 |
| IL87226A (en) | 1993-04-04 |
| AU2025788A (en) | 1989-06-08 |
| NO883297L (no) | 1989-06-08 |
| DK168047B1 (da) | 1994-01-24 |
| KR890009930A (ko) | 1989-08-04 |
| NO883297D0 (no) | 1988-07-25 |
| EP0326640B1 (en) | 1993-04-28 |
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