ZA883315B - Renin inhibiters,their syntheses,and use - Google Patents

Renin inhibiters,their syntheses,and use

Info

Publication number
ZA883315B
ZA883315B ZA883315A ZA883315A ZA883315B ZA 883315 B ZA883315 B ZA 883315B ZA 883315 A ZA883315 A ZA 883315A ZA 883315 A ZA883315 A ZA 883315A ZA 883315 B ZA883315 B ZA 883315B
Authority
ZA
South Africa
Prior art keywords
inhibiters
renin
syntheses
renin inhibiters
Prior art date
Application number
ZA883315A
Other languages
English (en)
Inventor
Jan Olle Karlsson
Olle Karlsson Jan
Erik Morgan Herman Sohtell
Morgan Herman Sohtell Erik
Carl Ingemar Starke
Ingemar Starke Carl
Rolf Christer Westerlund
Christer Westerlund Rolf
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Priority to ZA883315A priority Critical patent/ZA883315B/xx
Publication of ZA883315B publication Critical patent/ZA883315B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Sub-Exchange Stations And Push- Button Telephones (AREA)
ZA883315A 1986-12-29 1988-05-10 Renin inhibiters,their syntheses,and use ZA883315B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ZA883315A ZA883315B (en) 1986-12-29 1988-05-10 Renin inhibiters,their syntheses,and use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8605573A SE8605573D0 (sv) 1986-12-29 1986-12-29 Novel compounds
ZA883315A ZA883315B (en) 1986-12-29 1988-05-10 Renin inhibiters,their syntheses,and use

Publications (1)

Publication Number Publication Date
ZA883315B true ZA883315B (en) 1990-01-31

Family

ID=20366760

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA883315A ZA883315B (en) 1986-12-29 1988-05-10 Renin inhibiters,their syntheses,and use

Country Status (13)

Country Link
EP (1) EP0273893A3 (sv)
JP (1) JPH02501735A (sv)
KR (1) KR890700131A (sv)
CN (1) CN1039017A (sv)
AU (1) AU600549B2 (sv)
DD (1) DD272306A5 (sv)
DK (1) DK469588A (sv)
FI (1) FI893155A (sv)
HU (1) HUT49892A (sv)
NO (1) NO883818D0 (sv)
SE (1) SE8605573D0 (sv)
WO (1) WO1988005049A1 (sv)
ZA (1) ZA883315B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8802428D0 (sv) * 1988-06-28 1988-06-28 Haessle Ab New compounds
US5215968A (en) * 1988-12-10 1993-06-01 Hoechst Aktiengesellschaft Dipeptide derivatives having an enzyme inhibitory action
DE3841732A1 (de) * 1988-12-10 1990-06-13 Hoechst Ag Dipeptid-derivate mit enzym-inhibitorischer wirkung
US5198426A (en) * 1988-12-30 1993-03-30 Warner-Lambert Company Renin inhibitors containing c-terminal dihydroxy amides
AU7032391A (en) * 1989-12-22 1991-07-24 Astra Aktiebolag New amides
DE4004898A1 (de) * 1990-02-16 1991-08-22 Merck Patent Gmbh Peptid-analoga

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT995110B (it) * 1973-08-01 1975-11-10 Snam Progetti Procedimento per la produzione di composti eterociclici e prodotti ottenuti
EP0316965A3 (en) * 1983-02-07 1989-08-09 Aktiebolaget Hässle Enzyme inhibitors
JPS59227851A (ja) * 1983-06-09 1984-12-21 Sankyo Co Ltd レニン阻害作用を有するペプチド類
JPS60199884A (ja) * 1984-03-26 1985-10-09 Microbial Chem Res Found ベスタチン類の新規製造法
EP0163237A3 (en) * 1984-05-29 1988-04-27 Merck & Co. Inc. Di- and tri-peptidal renin inhibitors
US4652551A (en) * 1984-06-22 1987-03-24 Abbott Laboratories Renin inhibiting compounds
US4645759A (en) * 1984-06-22 1987-02-24 Abbott Laboratories Renin inhibiting compounds
FI88400C (sv) * 1984-08-06 1993-05-10 Upjohn Co Förfarande för framställning av renin inhiberande peptider
EP0258289A4 (en) * 1986-01-16 1991-01-02 Joseph Dellaria Peptide analogs

Also Published As

Publication number Publication date
SE8605573D0 (sv) 1986-12-29
DK469588D0 (da) 1988-08-22
AU600549B2 (en) 1990-08-16
JPH02501735A (ja) 1990-06-14
HUT49892A (en) 1989-11-28
WO1988005049A1 (en) 1988-07-14
EP0273893A2 (en) 1988-07-06
NO883818L (no) 1988-08-26
FI893155A0 (fi) 1989-06-28
NO883818D0 (no) 1988-08-26
DK469588A (da) 1988-08-22
CN1039017A (zh) 1990-01-24
FI893155A (fi) 1989-06-28
DD272306A5 (de) 1989-10-04
EP0273893A3 (en) 1988-09-21
KR890700131A (ko) 1989-03-10
AU1108488A (en) 1988-07-27

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