ZA881726B - Method of treating anxiety with tetrahydrobenz(c,d)indole-6-carbozamides - Google Patents
Method of treating anxiety with tetrahydrobenz(c,d)indole-6-carbozamidesInfo
- Publication number
- ZA881726B ZA881726B ZA881726A ZA881726A ZA881726B ZA 881726 B ZA881726 B ZA 881726B ZA 881726 A ZA881726 A ZA 881726A ZA 881726 A ZA881726 A ZA 881726A ZA 881726 B ZA881726 B ZA 881726B
- Authority
- ZA
- South Africa
- Prior art keywords
- carbozamides
- tetrahydrobenz
- indole
- treating anxiety
- allyl
- Prior art date
Links
- 208000019901 Anxiety disease Diseases 0.000 title abstract 2
- 230000036506 anxiety Effects 0.000 title abstract 2
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/025,291 US4745126A (en) | 1987-03-12 | 1987-03-12 | Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA881726B true ZA881726B (en) | 1989-11-29 |
Family
ID=21825165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA881726A ZA881726B (en) | 1987-03-12 | 1988-03-10 | Method of treating anxiety with tetrahydrobenz(c,d)indole-6-carbozamides |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4745126A (en:Method) |
| EP (1) | EP0285278B1 (en:Method) |
| JP (1) | JP2513770B2 (en:Method) |
| KR (1) | KR960006065B1 (en:Method) |
| AT (1) | ATE79257T1 (en:Method) |
| AU (1) | AU609097B2 (en:Method) |
| CA (1) | CA1313823C (en:Method) |
| DE (1) | DE3873578T2 (en:Method) |
| DK (1) | DK175197B1 (en:Method) |
| ES (1) | ES2051834T3 (en:Method) |
| GR (1) | GR3005990T3 (en:Method) |
| HU (1) | HU203664B (en:Method) |
| PH (1) | PH24139A (en:Method) |
| ZA (1) | ZA881726B (en:Method) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5204340A (en) * | 1989-04-11 | 1993-04-20 | Eli Lilly And Company | Tetrahydrobenz(c,d)indole serotonin agonists |
| US5212319A (en) * | 1990-02-26 | 1993-05-18 | Eli Lilly And Company | Intermediates to 4-amino-hexahydrobenz[cd]indoles and processes therefor |
| US5302612A (en) * | 1990-02-26 | 1994-04-12 | Eli Lilly And Company | 6-substituted-hexahydrobenz[cd]indoles |
| TW219933B (en:Method) * | 1990-02-26 | 1994-02-01 | Lilly Co Eli | |
| US5258379A (en) * | 1990-05-04 | 1993-11-02 | Eli Lilly And Company | Method of inhibiting gastric acid secretion with n-arylpiperazines |
| US5096908A (en) * | 1990-05-04 | 1992-03-17 | Eli Lilly And Company | Method of inhibiting gastric acid secretion |
| US5340838A (en) * | 1990-05-04 | 1994-08-23 | Eli Lilly And Company | Method of inhibiting gastric acid secretion with 2-phenylcyclopropylamines |
| US5229410A (en) * | 1990-08-15 | 1993-07-20 | Eli Lilly And Company | 6-substituted-hexahydrobenz[cd]indoles |
| US5229409A (en) * | 1990-08-15 | 1993-07-20 | Eli Lilly And Company | 6-substituted-tetrahydrobenz[cd]indoles |
| US5244912A (en) * | 1991-03-28 | 1993-09-14 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof |
| US5364856A (en) * | 1991-03-28 | 1994-11-15 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles |
| US5641794A (en) * | 1991-03-28 | 1997-06-24 | Eli Lilly Company | 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles |
| US5244911A (en) * | 1991-03-28 | 1993-09-14 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof |
| US5347013A (en) * | 1991-03-28 | 1994-09-13 | Eli Lilly And Company | 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles |
| CZ285829B6 (cs) * | 1993-06-10 | 1999-11-17 | Eli Lilly And Company | Použití derivátu tetrahydrobenz [c,d]indolu pro výrobu farmaceutického prostředku vhodného pro ošetřování sexuální dysfunkce |
| US5385928A (en) * | 1994-05-18 | 1995-01-31 | Eli Lilly And Company | Tetrahydrobenz [CD] indazoles, compositions and use |
| US6391922B1 (en) | 1998-01-13 | 2002-05-21 | Synchroneuron, Llc | Treatment of posttraumatic stress disorder, obsessive-compulsive disorder and related neuropsychiatric disorders |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3346573A1 (de) * | 1983-12-23 | 1985-07-04 | Troponwerke GmbH & Co KG, 5000 Köln | 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung |
| US4576959A (en) * | 1984-02-06 | 1986-03-18 | Eli Lilly And Company | 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles |
| IL74222A (en) * | 1984-02-06 | 1988-07-31 | Lilly Co Eli | 6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them |
-
1987
- 1987-03-12 US US07/025,291 patent/US4745126A/en not_active Expired - Lifetime
-
1988
- 1988-03-09 PH PH36611A patent/PH24139A/en unknown
- 1988-03-10 EP EP88302073A patent/EP0285278B1/en not_active Expired - Lifetime
- 1988-03-10 ZA ZA881726A patent/ZA881726B/xx unknown
- 1988-03-10 AT AT88302073T patent/ATE79257T1/de not_active IP Right Cessation
- 1988-03-10 DE DE8888302073T patent/DE3873578T2/de not_active Expired - Fee Related
- 1988-03-10 ES ES88302073T patent/ES2051834T3/es not_active Expired - Lifetime
- 1988-03-10 CA CA000561048A patent/CA1313823C/en not_active Expired - Fee Related
- 1988-03-11 HU HU881179A patent/HU203664B/hu not_active IP Right Cessation
- 1988-03-11 DK DK198801321A patent/DK175197B1/da not_active IP Right Cessation
- 1988-03-11 AU AU13023/88A patent/AU609097B2/en not_active Ceased
- 1988-03-11 KR KR1019880002504A patent/KR960006065B1/ko not_active Expired - Fee Related
- 1988-03-11 JP JP63059191A patent/JP2513770B2/ja not_active Expired - Fee Related
-
1992
- 1992-10-15 GR GR920402309T patent/GR3005990T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH24139A (en) | 1990-03-22 |
| EP0285278B1 (en) | 1992-08-12 |
| CA1313823C (en) | 1993-02-23 |
| ATE79257T1 (de) | 1992-08-15 |
| US4745126A (en) | 1988-05-17 |
| DE3873578D1 (de) | 1992-09-17 |
| DE3873578T2 (de) | 1993-03-04 |
| EP0285278A3 (en) | 1990-05-09 |
| AU1302388A (en) | 1988-09-15 |
| EP0285278A2 (en) | 1988-10-05 |
| DK132188D0 (da) | 1988-03-11 |
| DK175197B1 (da) | 2004-07-05 |
| KR880010770A (ko) | 1988-10-24 |
| ES2051834T3 (es) | 1994-07-01 |
| GR3005990T3 (en:Method) | 1993-06-07 |
| JP2513770B2 (ja) | 1996-07-03 |
| JPS63243026A (ja) | 1988-10-07 |
| HU203664B (en) | 1991-09-30 |
| KR960006065B1 (ko) | 1996-05-08 |
| DK132188A (da) | 1988-09-13 |
| AU609097B2 (en) | 1991-04-26 |
| HUT46536A (en) | 1988-11-28 |
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