ZA878430B - Stable immobilized hapten reagent for use in heterogenous immunometric assays - Google Patents

Stable immobilized hapten reagent for use in heterogenous immunometric assays

Info

Publication number
ZA878430B
ZA878430B ZA878430A ZA878430A ZA878430B ZA 878430 B ZA878430 B ZA 878430B ZA 878430 A ZA878430 A ZA 878430A ZA 878430 A ZA878430 A ZA 878430A ZA 878430 B ZA878430 B ZA 878430B
Authority
ZA
South Africa
Prior art keywords
hapten
reagent
immobilized
moiety
gel particle
Prior art date
Application number
ZA878430A
Other languages
English (en)
Inventor
D. Johnson Richard
Volker Runzheimer H.
G. Sommer Ronald
Yip Kin-Fai
Original Assignee
Miles Laboratories Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc. filed Critical Miles Laboratories Inc.
Publication of ZA878430B publication Critical patent/ZA878430B/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/548—Carbohydrates, e.g. dextran
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
ZA878430A 1986-12-09 1987-11-10 Stable immobilized hapten reagent for use in heterogenous immunometric assays ZA878430B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/939,902 US4822747A (en) 1986-12-09 1986-12-09 Polyacrylamide gel particles having hapten moieties bound thereto as immunoassay reagent

Publications (1)

Publication Number Publication Date
ZA878430B true ZA878430B (en) 1988-05-05

Family

ID=25473911

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA878430A ZA878430B (en) 1986-12-09 1987-11-10 Stable immobilized hapten reagent for use in heterogenous immunometric assays

Country Status (12)

Country Link
US (1) US4822747A (xx)
EP (1) EP0270937B1 (xx)
JP (1) JPH063449B2 (xx)
AT (1) ATE80950T1 (xx)
AU (1) AU585470B2 (xx)
CA (1) CA1288691C (xx)
DE (1) DE3781870T2 (xx)
DK (1) DK643987A (xx)
ES (1) ES2044896T3 (xx)
IL (1) IL83894A (xx)
NO (1) NO172459B (xx)
ZA (1) ZA878430B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5237016A (en) * 1989-01-05 1993-08-17 Siska Diagnostics, Inc. End-attachment of oligonucleotides to polyacrylamide solid supports for capture and detection of nucleic acids
US5045480A (en) * 1989-02-09 1991-09-03 Miles Inc. Gel particles having hapten moieties bound thereto as immunoassay reagent
WO1994022918A1 (en) * 1993-03-29 1994-10-13 Minnesota Mining And Manufacturing Company Method of coupling ligands within porous supports (p.e. azlactone) and uses thereof
US5613190A (en) * 1995-05-01 1997-03-18 Bell Atlantic Network Services, Inc. Customer premise wireless distribution of audio-video, control signals and voice
US6177282B1 (en) * 1997-08-12 2001-01-23 Mcintyre John A. Antigens embedded in thermoplastic
US6066446A (en) * 1997-12-19 2000-05-23 Nen Life Science Products, Inc. Assay member and method for its manufacture
CA2283597C (en) 1998-10-02 2008-02-05 Ortho-Clinical Diagnostics, Inc. Reduced cortisol conjugates
JP2002372539A (ja) * 2001-06-13 2002-12-26 Towns:Kk 非蛋白性物質に対する抗体の検出方法及び装置
JP2007240509A (ja) * 2006-03-12 2007-09-20 Ultizyme International Ltd 分子認識ポリマー及びその製造方法、分子認識ポリマーを用いた固相抽出方法
EP2523966B1 (en) 2010-01-15 2017-10-04 Suzhou Neupharma Co., Ltd Certain chemical entities, compositions, and methods
CN102656179B (zh) 2010-08-28 2015-07-29 苏州润新生物科技有限公司 蟾蜍灵衍生物、其药物组合物及用途
CN103619865B (zh) * 2011-02-02 2016-10-12 苏州润新生物科技有限公司 某些化学个体、组合物及方法
CN109354598A (zh) 2012-04-29 2019-02-19 润新生物公司 化学个体、药物组合物及癌症治疗方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3793445A (en) * 1970-04-29 1974-02-19 Wisconsin Alumni Res Found Reagent for radioimmunoassay
US3966897A (en) * 1973-04-02 1976-06-29 Marine Colloids, Inc. Medium for use in bioassay and method of using same
US3925017A (en) * 1973-05-01 1975-12-09 Wisconsin Alumni Res Found Preparation of dry, porous gel particles having high water regain for liquid sampling
FR2334106A1 (fr) * 1975-12-02 1977-07-01 Pasteur Institut Gel magnetique convenant pour dosages immunoenzymatiques
AU533026B2 (en) * 1979-10-26 1983-10-27 Dynasciences Corp. Passively adsorbing immuno-reactive haptens to solid phases
US4446232A (en) * 1981-10-13 1984-05-01 Liotta Lance A Enzyme immunoassay with two-zoned device having bound antigens
JPS58214854A (ja) * 1982-06-08 1983-12-14 Konishiroku Photo Ind Co Ltd 免疫用分析素材
US4551426A (en) * 1983-10-03 1985-11-05 E. I. Du Pont De Nemours And Company Heterogeneous immunoassay for digoxin using ouabain as a separation means
CA1339952C (en) * 1984-10-29 1998-07-14 William J. Knowles Immunoassays for denatured protein analytes, particularly hb alc, and monoclonal antibodies thereto

Also Published As

Publication number Publication date
NO874937L (no) 1988-06-10
JPH063449B2 (ja) 1994-01-12
EP0270937B1 (en) 1992-09-23
EP0270937A3 (en) 1990-09-19
IL83894A0 (en) 1988-02-29
JPS63163166A (ja) 1988-07-06
EP0270937A2 (en) 1988-06-15
NO172459B (no) 1993-04-13
DK643987D0 (da) 1987-12-08
ES2044896T3 (es) 1994-01-16
AU8190687A (en) 1988-06-09
DE3781870D1 (de) 1992-10-29
DK643987A (da) 1988-05-10
NO874937D0 (no) 1987-11-26
AU585470B2 (en) 1989-06-15
US4822747A (en) 1989-04-18
ATE80950T1 (de) 1992-10-15
IL83894A (en) 1991-06-10
DE3781870T2 (de) 1993-02-11
CA1288691C (en) 1991-09-10

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