ZA874430B - New polypeptides,their preparation and use - Google Patents

New polypeptides,their preparation and use

Info

Publication number
ZA874430B
ZA874430B ZA874430A ZA874430A ZA874430B ZA 874430 B ZA874430 B ZA 874430B ZA 874430 A ZA874430 A ZA 874430A ZA 874430 A ZA874430 A ZA 874430A ZA 874430 B ZA874430 B ZA 874430B
Authority
ZA
South Africa
Prior art keywords
preparation
new polypeptides
polypeptides
lymphotoxin
new
Prior art date
Application number
ZA874430A
Other languages
English (en)
Inventor
Klaus Schollmeier
Schollmeier Klaus
Achim Moeller
Moeller Achim
Wolfgang Koerwer
Koerwer Wolfgang
Thomas Doerper
Doerper Thomas
Heinz Hillen
Hillen Heinz
Lothar Daum
Daum Lothar
Franz Emling
Emling Franz
Gerhard Keilhauer
Keilhauer Gerhard
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of ZA874430B publication Critical patent/ZA874430B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/143—Lymphotoxin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/144—Tumor necrosis factor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA874430A 1986-06-20 1987-06-19 New polypeptides,their preparation and use ZA874430B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863620656 DE3620656A1 (de) 1986-06-20 1986-06-20 Polypeptide mit lymphotoxin-aktivitaet oder lymphotoxin-aehnlicher aktivitaet, ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
ZA874430B true ZA874430B (en) 1989-02-22

Family

ID=6303309

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA874430A ZA874430B (en) 1986-06-20 1987-06-19 New polypeptides,their preparation and use

Country Status (11)

Country Link
US (1) US5157106A (xx)
EP (1) EP0250000B1 (xx)
JP (1) JPS635099A (xx)
AT (1) ATE82329T1 (xx)
AU (1) AU590861B2 (xx)
DE (2) DE3620656A1 (xx)
DK (1) DK312787A (xx)
ES (1) ES2052513T3 (xx)
FI (1) FI872635A (xx)
HU (1) HU202922B (xx)
ZA (1) ZA874430B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6330426A (ja) * 1986-07-25 1988-02-09 Mitsubishi Chem Ind Ltd 自己免疫性疾患治療薬
FI884798A (fi) * 1987-10-28 1989-04-29 Eisai Co Ltd Rekombinantlymfotoxin.
CA1329119C (en) * 1988-03-29 1994-05-03 Milton David Goldenberg Cytotoxic therapy
US5120525A (en) * 1988-03-29 1992-06-09 Immunomedics, Inc. Radiolabeled antibody cytotoxic therapy of cancer
EP0336383A3 (en) * 1988-04-07 1990-08-16 Takeda Chemical Industries, Ltd. Novel recombinant human lymphotoxin
JPH023698A (ja) * 1988-06-20 1990-01-09 Denki Kagaku Kogyo Kk ヒトリンホトキシンに対するモノクローナル抗体及びそれら抗体を産生するハイブリドーマ、並びにそれら抗体を用いたヒトリンホトキシンの精製方法、測定方法及び測定試薬
CA2001756A1 (en) * 1988-10-31 1991-04-30 Seiichi Uesugi New human lymphotoxin n-end deletion mutant
DE3841754A1 (de) * 1988-12-12 1990-06-13 Basf Ag Neue tnf-peptide
DE3841759A1 (de) * 1988-12-12 1990-06-13 Basf Ag Neue tnf-peptide

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568640A (en) * 1981-05-11 1986-02-04 Harvey Rubin Method of inserting amino acid analogs into proteins
DE3376224D1 (en) * 1982-05-25 1988-05-11 Univ Brandeis Cloning vector with indicator genes which have been inactivated by frameshift
IL75318A (en) * 1984-05-31 1994-08-26 Genentech Inc Recombinant human memotoxin and methods for its recombinant production
US4677064A (en) * 1984-11-09 1987-06-30 Cetus Corporation Human tumor necrosis factor
US4677063A (en) * 1985-05-02 1987-06-30 Cetus Corporation Human tumor necrosis factor
US4752575A (en) * 1984-11-26 1988-06-21 The Regents Of The University Of California Lymphotoxins with antitumor activity and method for producing same
AU603768B2 (en) * 1985-07-04 1990-11-29 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Lymphotoxin dna, lymphotoxin expression vector, lymphotoxin resistant cell, transformant with lymphotoxin expression vector and process for preparing lymphotoxin
US4782139A (en) * 1985-10-28 1988-11-01 Eli Lilly And Company Selective chemical removal of a protein amino-terminal residue
JPS62181298A (ja) * 1986-02-05 1987-08-08 Kyowa Hakko Kogyo Co Ltd ヒトリンホトキシンポリペプチド誘導体
FI884798A (fi) * 1987-10-28 1989-04-29 Eisai Co Ltd Rekombinantlymfotoxin.

Also Published As

Publication number Publication date
US5157106A (en) 1992-10-20
DK312787D0 (da) 1987-06-19
JPS635099A (ja) 1988-01-11
EP0250000A3 (en) 1988-05-04
ATE82329T1 (de) 1992-11-15
FI872635A0 (fi) 1987-06-12
EP0250000A2 (de) 1987-12-23
DK312787A (da) 1987-12-21
HU202922B (en) 1991-04-29
AU7452187A (en) 1988-01-07
EP0250000B1 (de) 1992-11-11
FI872635A (fi) 1987-12-21
ES2052513T3 (es) 1994-07-16
DE3782549D1 (de) 1992-12-17
AU590861B2 (en) 1989-11-16
HUT44609A (en) 1988-03-28
DE3620656A1 (de) 1987-12-23

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