ZA874036B - Use of 12-amino-pyrridazino(4',5':3,4)-pyrrolo-(2,1-a)-isoquinolines as cardioprotective and neuroprotective agents - Google Patents

Use of 12-amino-pyrridazino(4',5':3,4)-pyrrolo-(2,1-a)-isoquinolines as cardioprotective and neuroprotective agents

Info

Publication number
ZA874036B
ZA874036B ZA874036A ZA874036A ZA874036B ZA 874036 B ZA874036 B ZA 874036B ZA 874036 A ZA874036 A ZA 874036A ZA 874036 A ZA874036 A ZA 874036A ZA 874036 B ZA874036 B ZA 874036B
Authority
ZA
South Africa
Prior art keywords
pyrridazino
isoquinolines
cardioprotective
pyrrolo
amino
Prior art date
Application number
ZA874036A
Other languages
English (en)
Inventor
Walter Loesel
Loesel Walter
Otto Roos
Roos Otto
Gerd Schnorrenberg
Schnorrenberg Gerd
Dietrich Arndts
Arndts Dietrich
George Speck
Speck George
Helmut Ensinger
Ensinger Helmut
Franz-Josef Kuhn
Kuhn Franz-Josef
Erich Lehr
Lehr Erich
Dieter Hinzen
Hinzen Dieter
Guenter Schingnitz
Schingnitz Guenter
Richard Reichl
Reichl Richard
Ilse Streller
Streller Ilse
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of ZA874036B publication Critical patent/ZA874036B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA874036A 1986-06-06 1987-06-05 Use of 12-amino-pyrridazino(4',5':3,4)-pyrrolo-(2,1-a)-isoquinolines as cardioprotective and neuroprotective agents ZA874036B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863619099 DE3619099A1 (de) 1986-06-06 1986-06-06 Verwendung von 12-amino-pyrridazino(4',5' : 3,4)pyrrolo-(2,1-a)-isochinolinen als cardio- und neuroprotektive mittel

Publications (1)

Publication Number Publication Date
ZA874036B true ZA874036B (en) 1989-02-22

Family

ID=6302443

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA874036A ZA874036B (en) 1986-06-06 1987-06-05 Use of 12-amino-pyrridazino(4',5':3,4)-pyrrolo-(2,1-a)-isoquinolines as cardioprotective and neuroprotective agents

Country Status (4)

Country Link
EP (1) EP0252299A3 (ja)
JP (1) JPH07116040B2 (ja)
DE (1) DE3619099A1 (ja)
ZA (1) ZA874036B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE157665T1 (de) * 1992-06-22 1997-09-15 Boehringer Ingelheim Kg 9-amino-pyridazino 4',5' : 3,4>pyrrolo- 2,1- a>isochinoline und deren verwendung für die herstellung von pharmazeutischen zubereitungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3401018A1 (de) * 1984-01-13 1985-07-18 Boehringer Ingelheim KG, 6507 Ingelheim Verfahren zur herstellung von 5,6-dihydro-pyrrolo(2,1-a)isochinolinen
EP0190563B1 (de) * 1985-01-14 1989-08-02 Boehringer Ingelheim Kg Neue 12-Amino-pyridazino[4',5':3,4]pyrrolo-[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und ihre Verwendung
DE8502008U1 (de) * 1985-01-26 1985-08-29 Celamerck Gmbh & Co Kg, 6507 Ingelheim Verschlußkappe für Zweikomponentenpackungen

Also Published As

Publication number Publication date
EP0252299A3 (de) 1990-04-11
JPH07116040B2 (ja) 1995-12-13
JPS63115879A (ja) 1988-05-20
EP0252299A2 (de) 1988-01-13
DE3619099A1 (de) 1987-12-10

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