ZA873169B - Novel heterocyclic compounds - Google Patents

Novel heterocyclic compounds

Info

Publication number
ZA873169B
ZA873169B ZA873169A ZA873169A ZA873169B ZA 873169 B ZA873169 B ZA 873169B ZA 873169 A ZA873169 A ZA 873169A ZA 873169 A ZA873169 A ZA 873169A ZA 873169 B ZA873169 B ZA 873169B
Authority
ZA
South Africa
Prior art keywords
heterocyclic compounds
novel heterocyclic
novel
compounds
heterocyclic
Prior art date
Application number
ZA873169A
Other languages
English (en)
Inventor
Lee James Beeley
James Beeley Lee
John Berge
Berge John
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of ZA873169B publication Critical patent/ZA873169B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/28—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/18—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA873169A 1986-05-03 1987-05-04 Novel heterocyclic compounds ZA873169B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868610909A GB8610909D0 (en) 1986-05-03 1986-05-03 Compounds

Publications (1)

Publication Number Publication Date
ZA873169B true ZA873169B (en) 1988-04-27

Family

ID=10597340

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA873169A ZA873169B (en) 1986-05-03 1987-05-04 Novel heterocyclic compounds

Country Status (12)

Country Link
US (1) US4861789A (fr)
EP (1) EP0251453B1 (fr)
JP (1) JPS62267270A (fr)
AU (1) AU600939B2 (fr)
DE (1) DE3767789D1 (fr)
DK (1) DK227487A (fr)
ES (1) ES2031890T3 (fr)
GB (1) GB8610909D0 (fr)
GR (1) GR3001416T3 (fr)
NZ (1) NZ220179A (fr)
PT (1) PT84818B (fr)
ZA (1) ZA873169B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034406A (en) * 1989-09-26 1991-07-23 Allergan, Inc. Method for reducing or maintaining intraocular pressure
US5066664A (en) * 1990-02-28 1991-11-19 Allergan, Inc. 2-(hydroxy-2-alkylphenylamino)-oxazolines and thiazolines as anti-glaucoma and vasoconstrictive agents
DK148292D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Forbindelser
US5580892A (en) * 1993-10-22 1996-12-03 Allergan Method for using 2-(2-alkylphenylamino)-oxazolines as adrenergic agents
WO1996001813A1 (fr) * 1994-07-11 1996-01-25 Allergan DERIVES BICYCLIQUES A CONFORMATION RIGIDE ET D'ADAMANTANE UTILES EN TANT QU'α2-ADRENOLYTIQUE
US6150389A (en) * 1994-07-11 2000-11-21 Allergan Sales, Inc. Comformationally rigid bicyclic and adamantane derivatives useful as α2 -adrenergic blocking agents
DE19514579A1 (de) 1995-04-20 1996-10-24 Boehringer Ingelheim Kg Verwendung von alpha¶1¶¶L¶-Agonisten zur Behandlung der Harninkontinenz
US5677321A (en) * 1996-02-29 1997-10-14 Synaptic Pharmaceutical Corporation 5- and 6-(2-imidazolin-2-ylamino) and -(2-thiazolin-2-ylamino)-benzothiazoles as alpha-2 adrenergic ligands
BRPI0707868A2 (pt) 2006-02-15 2011-05-10 Bayer Cropscience Ag inseticidas derivados de aminaheteroarila e heterocÍclicos substituÍdos, composiÇço inseticida e processo para o controle de insetos
EP1988080A1 (fr) * 2007-05-03 2008-11-05 Bayer CropScience AG 2-aminoindanes substitués insecticides
WO2008145615A2 (fr) * 2007-05-25 2008-12-04 Basf Se Dérivés d'aminoazoline et d'urée pour lutter contre des nuisibles animaux
WO2009023757A1 (fr) * 2007-08-15 2009-02-19 Allergan, Inc. Composés thérapeutiques
JP5433576B2 (ja) * 2007-08-15 2014-03-05 アラーガン インコーポレイテッド アドレナリン作動化合物
AU2008286824B2 (en) * 2007-08-15 2014-10-02 Allergan, Inc. Heterocyclyl substituted fused carbocyles useful in the treatment of conditions such as glaucoma and pain
DK2240468T3 (da) * 2008-01-18 2014-01-20 Allergan Inc Selektive adrenerge stoffer af undertype alpha 2 og fremgangsmåder til fremstilling heraf

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2870159A (en) * 1957-07-08 1959-01-20 Pfizer & Co C Hydrogenated 2-(1-naphthylamino)-oxazolines
US2870161A (en) * 1957-07-08 1959-01-20 Pfizer & Co C 2-(1-indanyl amino)-oxazolines
US2883410A (en) * 1957-07-08 1959-04-21 Pfizer & Co C N-(1-indanyl)-n'-(beta-substituted ethyl)-ureas
DE1195323B (de) * 1963-06-24 1965-06-24 Thomae Gmbh Dr K Verfahren zur Herstellung von 2-[5', 6', 7', 8'-Tetrahydronaphthyl-(1')-amino]-imidazolin und seinen Salzen
US3432600A (en) * 1963-09-30 1969-03-11 Du Pont Partially reduced 2-(1-napthylamino) oxazoline,indanylethylureas,and indanylaminooxazoline
US3679798A (en) * 1964-02-28 1972-07-25 Du Pont Composition comprising arylaminooxazoline and antichloligeneric agent
DE1670753A1 (de) * 1966-09-27 1970-07-16 Bayer Ag Verfahren zur Herstellung von 2-Cycloalkylaminooxazolinen
DE1670751A1 (de) * 1966-09-27 1970-12-23 Bayer Ag Verfahren zur Herstellung von 2-Phenylamino-2-oxazolinen
US3882229A (en) * 1972-07-21 1975-05-06 Nordmark Werke Gmbh Composition and method for shrinking mucous membranes
JPS54151990A (en) * 1978-04-17 1979-11-29 Beiersdorf Ag Novel condensated nitrogenncontained heterocyclic compound and its manufacture

Also Published As

Publication number Publication date
AU7247987A (en) 1987-11-05
JPS62267270A (ja) 1987-11-19
EP0251453B1 (fr) 1991-01-30
DE3767789D1 (de) 1991-03-07
DK227487A (da) 1987-11-04
NZ220179A (en) 1989-10-27
EP0251453A2 (fr) 1988-01-07
US4861789A (en) 1989-08-29
PT84818A (en) 1987-06-01
ES2031890T3 (es) 1993-01-01
PT84818B (pt) 1989-12-29
AU600939B2 (en) 1990-08-30
GB8610909D0 (en) 1986-06-11
DK227487D0 (da) 1987-05-04
GR3001416T3 (en) 1992-09-25
EP0251453A3 (en) 1988-09-28

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