ZA872782B - New immunomodulators obtained semisynthetically from a bacterial polysaccharide isolated from a non-encapsulated mutant strain of klebsiella pneumoniae - Google Patents

New immunomodulators obtained semisynthetically from a bacterial polysaccharide isolated from a non-encapsulated mutant strain of klebsiella pneumoniae

Info

Publication number
ZA872782B
ZA872782B ZA872782A ZA872782A ZA872782B ZA 872782 B ZA872782 B ZA 872782B ZA 872782 A ZA872782 A ZA 872782A ZA 872782 A ZA872782 A ZA 872782A ZA 872782 B ZA872782 B ZA 872782B
Authority
ZA
South Africa
Prior art keywords
semisynthetically
mutant strain
klebsiella pneumoniae
bacterial polysaccharide
polysaccharide isolated
Prior art date
Application number
ZA872782A
Other languages
English (en)
Inventor
Dussourd D'hinterland Lucien
Normier Gerard
Pinel Anne-Marie
Original Assignee
Pierre Fabre Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament filed Critical Pierre Fabre Medicament
Publication of ZA872782B publication Critical patent/ZA872782B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
ZA872782A 1986-05-12 1987-04-21 New immunomodulators obtained semisynthetically from a bacterial polysaccharide isolated from a non-encapsulated mutant strain of klebsiella pneumoniae ZA872782B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8606765A FR2598434B1 (fr) 1986-05-12 1986-05-12 Nouveaux immunomodulateurs obtenus par hemisynthese a partir d'un polysaccharide bacterien isole d'une souche mutante non capsulee de klebsiella pneumoniae

Publications (1)

Publication Number Publication Date
ZA872782B true ZA872782B (en) 1987-10-05

Family

ID=9335114

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA872782A ZA872782B (en) 1986-05-12 1987-04-21 New immunomodulators obtained semisynthetically from a bacterial polysaccharide isolated from a non-encapsulated mutant strain of klebsiella pneumoniae

Country Status (11)

Country Link
US (1) US4933440A (de)
EP (1) EP0246149B1 (de)
JP (1) JP2662951B2 (de)
AT (1) ATE84075T1 (de)
AU (1) AU596652B2 (de)
CA (1) CA1268900A (de)
DE (1) DE3783268T2 (de)
ES (1) ES2052590T3 (de)
FR (1) FR2598434B1 (de)
GR (1) GR3007433T3 (de)
ZA (1) ZA872782B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2614306B1 (fr) * 1987-04-22 1989-07-28 Pf Medicament Nouveau derive de d.25, procede de preparation, utilisation a titre d'agent immunostimulant et compositions pharmaceutiques le contenant.
DE3812181A1 (de) * 1988-04-13 1989-10-26 Werner E G Prof Dr Mueller Arzneimittel, enthaltend natuerliche und/oder chemisch modifizierte mono- oder polysaccharide und deren verwendung
FR2644059B1 (fr) * 1989-03-08 1994-03-04 Fabre Medicament Pierre Compositions aerosols destinees a l'imagerie, au diagnostic et a la therapie ciblee de foyers inflammatoires et tumoraux
FR2655267B1 (fr) * 1989-12-04 1992-04-03 Roussel Uclaf Nouveau derive sulfate du galactanne extrait de klebsiella, procede de preparation, application a titre de medicaments et compositions pharmaceutiques le renfermant.
FR2659351B1 (fr) * 1990-03-08 1994-12-02 Pf Medicament Compose polysaccharidique delipide, procede de preparation, compositions en comprenant.
DE69408454T3 (de) † 1993-04-15 2004-06-09 Akzo Nobel N.V. Verfahren zur herstellung von amid-modifiziertem carboxyl enthaltenden polysaccharid und so erzeugtes fettsäureamid modifiziertes polysaccharid
US6444210B1 (en) 1996-07-03 2002-09-03 Her Majesty the Queen in right of Canada, as represented by the Minister of National Defence of Her Majesty′s Canadian Goverment Bacterial and synthetic polysaccharide immunomodulators that enhance general immunity
ITTS20010017A1 (it) * 2001-07-17 2003-01-17 Ct Ricerche Polytech Soc Coop Esteri polisaccaridici di acido retinoico.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL122086B1 (en) * 1979-04-09 1982-06-30 Politechnika Gdanska Process for preparing amides of antibiotics from the group of polyene macrolides and their derivativesvykh makrolidov i ikh proizvodnykh
FR2540136A1 (fr) * 1983-01-28 1984-08-03 Roussel Uclaf Nouveau procede de preparation d'acylglycoproteines immunostimulantes extraites de klebsiella pneumoniae, compositions pharmaceutiques et procede de lutte contre les maladies allergiques
US4476119A (en) * 1981-08-04 1984-10-09 Fidia S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
US4716223A (en) * 1981-08-04 1987-12-29 Fidia, S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
US4593091A (en) * 1981-08-04 1986-06-03 Fidia, S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
FR2523154A1 (fr) * 1982-03-09 1983-09-16 Fabre Sa Pierre Procede de preparation de proteoglycanes immunostimulants inducteurs d'interferon, proteoglycanes obtenus et medicaments les contenant
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
FR2570081B1 (fr) * 1984-09-10 1987-01-09 Pf Medicament Polysaccharides membranaires utiles notamment comme medicament et procede pour leur preparation
SE8405493D0 (sv) * 1984-11-01 1984-11-01 Bror Morein Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel
DE3445302A1 (de) * 1984-12-12 1986-06-12 Hoechst Ag, 6230 Frankfurt Extrazellulaeres polysaccharid, verfahren und stamm zu seiner herstellung und seine verwendung
US4755381A (en) * 1986-03-27 1988-07-05 Swiss Serum And Vaccine Institute Berne Klebsiella capsular polysaccharide vaccine

Also Published As

Publication number Publication date
FR2598434B1 (fr) 1988-09-16
ES2052590T3 (es) 1994-07-16
DE3783268T2 (de) 1993-05-19
US4933440A (en) 1990-06-12
FR2598434A1 (fr) 1987-11-13
EP0246149B1 (de) 1992-12-30
JPS62273201A (ja) 1987-11-27
JP2662951B2 (ja) 1997-10-15
DE3783268D1 (de) 1993-02-11
GR3007433T3 (de) 1993-07-30
ATE84075T1 (de) 1993-01-15
EP0246149A2 (de) 1987-11-19
EP0246149A3 (en) 1988-10-12
AU7141587A (en) 1987-11-19
CA1268900A (fr) 1990-05-08
AU596652B2 (en) 1990-05-10

Similar Documents

Publication Publication Date Title
AU586316B2 (en) Derivatives of cis, endo-2-azabicyclo-(3.3.0)-octane-3- carboxylic acid and a process for their preparation
AU577249B2 (en) Chewable mineral supplement
BG47496A3 (en) Method for preparing derivatives of benzamide
GR3000454T3 (en) Acid-pseudoplastic compositions
ZA872782B (en) New immunomodulators obtained semisynthetically from a bacterial polysaccharide isolated from a non-encapsulated mutant strain of klebsiella pneumoniae
AU8979782A (en) 13,14-didehydro prostaglandin esters or amides
ES8707967A1 (es) Un procedimiento para la preparacion de nuevos derivados de disacaridos o trisacaridos.
AU9009082A (en) 8 (uriedo/uriedo alkyl) ergolines and their thio- and imino-analogues
ES8605041A1 (es) Procedimiento de preparacion de polisacaridos membranarios de origen bacteriano
PL308203A1 (en) Synthesis of n-acetloneuraminic acid derivatives
AU1802983A (en) 2,2-dimethyl-5-phenoxypentanoic acid benzamides
AU568186B2 (en) Laidlomycin phenylcarbamate
GB2167079B (en) Process for the degradation of a viscous microbial polysaccharide formulation, a process for preparing an acid degradable polysaccharide formulation, and a polysaccharide formulation thereby obtained
AU8985891A (en) Method for the preparation of substituted and unsubstituted 2,3-pyridine and quinolinedicarboxylic acids
Burns Potential of a lactic acid bacterium for the biological preservation of ground beef
GB2104073B (en) Fluorinated diamino-heptene and -heptyne derivatives
DE3665574D1 (en) 3-hydroxy-dicarboxylic acids and process for their preparation
PL293562A1 (en) Method of obtaining 2,2-bis-/3,4-dimethyl-phenyl/-propane
AU3355684A (en) Preparation of tert-leucine
PH25252A (en) Novel microorganism and method for production of glutamic acid using the same
JPS57200344A (en) Propionic acid amide derivative
FR2654724B1 (fr) Sulfosalicylate d'hydrazine, procede pour sa preparation et application comme stabilisateur a effet antioxydant pour composes stanneux.
PL284525A1 (en) Method of obtaining 1,1,3,3-propanoteraphosphonic acid
IT1173550B (it) Sale di eritromicina con attivita'mucosecretolitica e fluidificante, processo per la sua preparazione e sue composizioni farmaceutiche
Sadeghieh Management of an exploration process