ZA868964B - Method for inhibiting post-surgical adhesion formation by the topical administration of non-steroidal anti-inflammatory drug - Google Patents

Method for inhibiting post-surgical adhesion formation by the topical administration of non-steroidal anti-inflammatory drug

Info

Publication number
ZA868964B
ZA868964B ZA868964A ZA868964A ZA868964B ZA 868964 B ZA868964 B ZA 868964B ZA 868964 A ZA868964 A ZA 868964A ZA 868964 A ZA868964 A ZA 868964A ZA 868964 B ZA868964 B ZA 868964B
Authority
ZA
South Africa
Prior art keywords
topical administration
steroidal anti
inflammatory drug
adhesion formation
surgical adhesion
Prior art date
Application number
ZA868964A
Other languages
English (en)
Inventor
Warren D Sheffield
Douglas B Johns
Shalaby W Shalaby
Gere S Dizerega
Leroy L Richer
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Publication of ZA868964B publication Critical patent/ZA868964B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA868964A 1985-11-27 1986-11-26 Method for inhibiting post-surgical adhesion formation by the topical administration of non-steroidal anti-inflammatory drug ZA868964B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80254585A 1985-11-27 1985-11-27

Publications (1)

Publication Number Publication Date
ZA868964B true ZA868964B (en) 1988-07-27

Family

ID=25183996

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA868964A ZA868964B (en) 1985-11-27 1986-11-26 Method for inhibiting post-surgical adhesion formation by the topical administration of non-steroidal anti-inflammatory drug

Country Status (3)

Country Link
US (1) US4937254A (ru)
IN (1) IN166447B (ru)
ZA (1) ZA868964B (ru)

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Also Published As

Publication number Publication date
US4937254A (en) 1990-06-26
US4937254B1 (ru) 1992-08-11
IN166447B (ru) 1990-05-12

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