ZA867617B - 3-vinyl-and 3-ethinyl-beta-carboline derivatives their production and their use as drugs - Google Patents
3-vinyl-and 3-ethinyl-beta-carboline derivatives their production and their use as drugsInfo
- Publication number
- ZA867617B ZA867617B ZA867617A ZA867617A ZA867617B ZA 867617 B ZA867617 B ZA 867617B ZA 867617 A ZA867617 A ZA 867617A ZA 867617 A ZA867617 A ZA 867617A ZA 867617 B ZA867617 B ZA 867617B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydrogen
- lower alkyl
- ethinyl
- drugs
- beta
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052736 halogen Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Transformer Cooling (AREA)
- Fats And Perfumes (AREA)
- Lubricants (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853535927 DE3535927A1 (de) | 1985-10-04 | 1985-10-04 | 3-vinyl- und 3-ethinyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA867617B true ZA867617B (en) | 1987-05-27 |
Family
ID=6283082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA867617A ZA867617B (en) | 1985-10-04 | 1986-10-06 | 3-vinyl-and 3-ethinyl-beta-carboline derivatives their production and their use as drugs |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4719210A (hu) |
| EP (1) | EP0218541B1 (hu) |
| JP (1) | JPH0772187B2 (hu) |
| AT (1) | ATE58535T1 (hu) |
| AU (1) | AU597001B2 (hu) |
| CA (1) | CA1266049A (hu) |
| DE (2) | DE3535927A1 (hu) |
| DK (1) | DK164554C (hu) |
| ES (1) | ES2039361T3 (hu) |
| FI (1) | FI84066C (hu) |
| GR (1) | GR3001356T3 (hu) |
| HU (1) | HU194881B (hu) |
| IE (1) | IE58897B1 (hu) |
| IL (1) | IL80216A0 (hu) |
| NO (1) | NO165072C (hu) |
| ZA (1) | ZA867617B (hu) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3608089A1 (de) * | 1986-03-08 | 1987-09-10 | Schering Ag | Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel |
| IL87563A (en) * | 1987-08-28 | 1993-08-18 | Schering Ag | Isoxazole-b-carboline derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same |
| US5585490A (en) * | 1991-10-08 | 1996-12-17 | Neurogen Corporation | Certain cycloalkyl and azacycloalkyl pyrrolopyrimidines; a new class of GABA brain receptor ligands |
| AU4117493A (en) * | 1992-04-08 | 1994-11-21 | Neurogen Corporation | Certain aryl fused pyrrolopyrimidines; a new class of gaba brain receptor ligands |
| US5367077A (en) * | 1992-04-08 | 1994-11-22 | Neurogen Corporation | Certain cycloalkyl and azacycloalkyl pyrrolopyridines; a new class of gaba rain receptor ligands |
| US5286860A (en) * | 1992-11-12 | 1994-02-15 | Neurogen Corporation | Certain aryl substituted pyrrolopyrazines; a new class of GABA brain receptor ligands |
| DE4308788A1 (de) * | 1993-03-18 | 1994-09-22 | Bayer Ag | Hetero-tricyclisch-substituierte Phenyl-cyclohexan-carbonsäurederivate |
| US5750702A (en) * | 1993-10-27 | 1998-05-12 | Neurogen Corporation | Certain pyrrolo pyridine-3-carboxamides; a new class of GABA brain receptor ligands |
| US5484944A (en) * | 1993-10-27 | 1996-01-16 | Neurogen Corporation | Certain fused pyrrolecarboxanilides and their use as GABA brain receptor ligands |
| DE19502753A1 (de) * | 1995-01-23 | 1996-07-25 | Schering Ag | Neue 9H-Pyrido[3,4-b]indol-Derivate |
| US5804686A (en) * | 1996-01-19 | 1998-09-08 | Neurogen Corporation | fused pyrrolecarboxamides; a new class of GABA brain receptor ligands |
| US6211365B1 (en) | 1996-01-19 | 2001-04-03 | Neurogen Corporation | Fused pyrrolecarboxamides; a new class of GABA brain receptor ligands |
| WO1997034870A1 (en) | 1996-03-22 | 1997-09-25 | Neurogen Corporation | Certain fused pyrrolecarboxamides as gaba brain receptor ligands |
| US5723462A (en) * | 1996-04-26 | 1998-03-03 | Neurogen Corporation | Certain fused pyrrolecarboxamides a new class of GABA brain receptor ligands |
| EE200200111A (et) | 1999-08-31 | 2003-06-16 | Neurogen Corporation | Kondenseerunud pürroolkarboksamiidid: aju GABA-retseptori ligandid |
| US20050014939A1 (en) * | 1999-08-31 | 2005-01-20 | Neurogen Corporation | Fused pyrrolecarboxamides: GABA brain receptor ligands |
| GB2452199A (en) | 2006-06-09 | 2009-02-25 | Igt Reno Nev | Progressive award selection in a wager game |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57123180A (en) * | 1980-12-17 | 1982-07-31 | Schering Ag | 3-substituted beta-carboline, manufacture and psychotropic drug containing same |
| DE3240514A1 (de) * | 1982-10-29 | 1984-05-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Ss-carboline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| DE3240511A1 (de) * | 1982-10-29 | 1984-05-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur herstellung von ss-carbolinderivaten |
| DE3240513A1 (de) * | 1982-10-29 | 1984-05-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Indolderivate, verfahren zu ihrer herstellung und deren verwendung zur weiterverarbeitung |
| DK149270C (da) * | 1983-05-27 | 1986-08-25 | Schering Ag | Analogifremgangsmaade til fremstilling af beta-carbolin-3-carboxylsyrederivater |
| DE3335323A1 (de) * | 1983-09-27 | 1985-04-04 | Schering AG, 1000 Berlin und 4709 Bergkamen | Substituierte ss-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
-
1985
- 1985-10-04 DE DE19853535927 patent/DE3535927A1/de not_active Withdrawn
-
1986
- 1986-10-02 DK DK471586A patent/DK164554C/da not_active IP Right Cessation
- 1986-10-02 IL IL80216A patent/IL80216A0/xx not_active IP Right Cessation
- 1986-10-03 DE DE8686730155T patent/DE3675733D1/de not_active Expired - Lifetime
- 1986-10-03 ES ES198686730155T patent/ES2039361T3/es not_active Expired - Lifetime
- 1986-10-03 EP EP86730155A patent/EP0218541B1/de not_active Expired - Lifetime
- 1986-10-03 HU HU864183A patent/HU194881B/hu not_active IP Right Cessation
- 1986-10-03 AT AT86730155T patent/ATE58535T1/de not_active IP Right Cessation
- 1986-10-03 FI FI864017A patent/FI84066C/fi not_active IP Right Cessation
- 1986-10-03 NO NO863961A patent/NO165072C/no unknown
- 1986-10-03 JP JP61234691A patent/JPH0772187B2/ja not_active Expired - Lifetime
- 1986-10-06 CA CA000519907A patent/CA1266049A/en not_active Expired - Lifetime
- 1986-10-06 ZA ZA867617A patent/ZA867617B/xx unknown
- 1986-10-06 US US06/915,360 patent/US4719210A/en not_active Expired - Fee Related
- 1986-10-06 IE IE263086A patent/IE58897B1/en not_active IP Right Cessation
- 1986-10-07 AU AU63663/86A patent/AU597001B2/en not_active Ceased
-
1991
- 1991-01-22 GR GR90401072T patent/GR3001356T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK471586A (da) | 1987-04-05 |
| DK164554C (da) | 1992-11-30 |
| NO863961D0 (no) | 1986-10-03 |
| EP0218541B1 (de) | 1990-11-22 |
| IE862630L (en) | 1987-04-04 |
| US4719210A (en) | 1988-01-12 |
| FI84066C (fi) | 1991-10-10 |
| HU194881B (en) | 1988-03-28 |
| DE3535927A1 (de) | 1987-04-09 |
| FI84066B (fi) | 1991-06-28 |
| IL80216A0 (en) | 1987-01-30 |
| DK471586D0 (da) | 1986-10-02 |
| NO165072C (no) | 1990-12-19 |
| AU597001B2 (en) | 1990-05-24 |
| DK164554B (da) | 1992-07-13 |
| FI864017A (fi) | 1987-04-05 |
| GR3001356T3 (en) | 1992-09-11 |
| AU6366386A (en) | 1987-04-09 |
| ES2039361T3 (es) | 1993-10-01 |
| JPH0772187B2 (ja) | 1995-08-02 |
| EP0218541A2 (de) | 1987-04-15 |
| HUT42092A (en) | 1987-06-29 |
| ATE58535T1 (de) | 1990-12-15 |
| JPS62174076A (ja) | 1987-07-30 |
| EP0218541A3 (en) | 1988-05-25 |
| FI864017A0 (fi) | 1986-10-03 |
| NO863961L (no) | 1987-04-06 |
| IE58897B1 (en) | 1993-12-01 |
| NO165072B (no) | 1990-09-10 |
| DE3675733D1 (de) | 1991-01-03 |
| CA1266049A (en) | 1990-02-20 |
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