ZA863304B - Pharmaceutical compositions containing pyridinones with antithrombotic effects and processes for preparing them - Google Patents

Pharmaceutical compositions containing pyridinones with antithrombotic effects and processes for preparing them

Info

Publication number
ZA863304B
ZA863304B ZA863304A ZA863304A ZA863304B ZA 863304 B ZA863304 B ZA 863304B ZA 863304 A ZA863304 A ZA 863304A ZA 863304 A ZA863304 A ZA 863304A ZA 863304 B ZA863304 B ZA 863304B
Authority
ZA
South Africa
Prior art keywords
pyridinones
preparing
processes
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA863304A
Other languages
English (en)
Inventor
Juergen Daemmgen
Helmut Ballhause
Walter Haarmann
Joachim Heider
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA863304B publication Critical patent/ZA863304B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA863304A 1985-05-03 1986-05-02 Pharmaceutical compositions containing pyridinones with antithrombotic effects and processes for preparing them ZA863304B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853515882 DE3515882A1 (de) 1985-05-03 1985-05-03 Arzneimittel, enthaltend pyridinone mit antithrombotischen wirkungen und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA863304B true ZA863304B (en) 1988-01-27

Family

ID=6269707

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA863304A ZA863304B (en) 1985-05-03 1986-05-02 Pharmaceutical compositions containing pyridinones with antithrombotic effects and processes for preparing them

Country Status (6)

Country Link
EP (1) EP0210342A2 (ja)
JP (1) JPS61254524A (ja)
AU (1) AU5706486A (ja)
DE (1) DE3515882A1 (ja)
DK (1) DK200586A (ja)
ZA (1) ZA863304B (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3533542B2 (ja) * 1994-03-08 2004-05-31 株式会社大塚製薬工場 ホスホン酸ジエステル誘導体
US6642244B2 (en) 2001-03-16 2003-11-04 Bristol-Myers Squibb Co. Pyrazolopyridopyrimidine inhibitors of cGMP phosphodiesterase
WO2006045010A2 (en) 2004-10-20 2006-04-27 Resverlogix Corp. Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases
CA2676984C (en) * 2007-02-01 2015-03-17 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular diseases
CN101531638B (zh) * 2008-03-13 2011-12-28 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
US8114995B2 (en) 2008-06-26 2012-02-14 Resverlogix Corp. Methods of preparing quinazolinone derivatives
CN101628913B (zh) 2008-07-18 2013-01-23 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
ES2542835T3 (es) * 2009-01-08 2015-08-12 Resverlogix Corporation Compuestos para la prevención y el tratamiento de enfermedades cardiovasculares
JP5795304B2 (ja) 2009-03-18 2015-10-14 レスバーロジックス コーポレイション 新規抗炎症剤
KR101892987B1 (ko) 2009-04-22 2018-08-30 리스버로직스 코퍼레이션 신규한 소염제
CA2851996C (en) 2011-11-01 2020-01-07 Resverlogix Corp. Pharmaceutical compositions for substituted quinazolinones
WO2014080290A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Cyclic amines as bromodomain inhibitors
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
EP2935253B1 (en) 2012-12-21 2018-08-01 Zenith Epigenetics Ltd. Novel heterocyclic compounds as bromodomain inhibitors
CA2977308A1 (en) 2015-03-13 2016-09-22 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases

Also Published As

Publication number Publication date
DE3515882A1 (de) 1986-11-06
DK200586D0 (da) 1986-05-01
AU5706486A (en) 1986-11-06
JPS61254524A (ja) 1986-11-12
EP0210342A2 (de) 1987-02-04
DK200586A (da) 1986-11-04

Similar Documents

Publication Publication Date Title
HUT40453A (en) Process for producing 11-beta-phenyl-gonanes and pharmaceutical compositions containing them
HUT41772A (en) Process for producing /4-substituted-piperazinyl- and -homopiperazinyl/-pyridazines and pharmaceutical compositions containing them
PT81746A (en) Process for the preparation of peptide-aldehydes and of pharmaceutical compositions containing them
IL74758A0 (en) Acyltripeptides and pharmaceutical compositions containing them
PH22863A (en) Pyrrolobenzimidazoles and pharmaceutical composition containing them
HUT41790A (en) Process for producing beta-amino-purine derivatives and pharmaceutical compositions containing them
PH21185A (en) 9a-aza-9a-homoerythromycin derivatives and pharmaceutical composition containing them
HUT44512A (en) Process for producing bensyl derivatives and pharmaceutical compositions containing them
ZA863304B (en) Pharmaceutical compositions containing pyridinones with antithrombotic effects and processes for preparing them
IL79376A (en) Substituted di-t-butylphenols and pharmaceutical compositions containing them
EG17710A (en) Process for the preparation isosilybin-free silbinin and pharmaceutical compositions containing them
HUT42478A (en) Process for producing gamma-carboline derivatives and pharmaceutical compositions containing them
HUT41035A (en) Process for producing cepheme derivatives and pharmaceutical compositions containing them
ZA862141B (en) Substituted 1,8-naphthyridinones,processes for their preparation and pharmaceutical compositions containing them
IL86711A0 (en) 5-pyrimidinecarboxamide derivatives and pharmaceutical compositions containing them
HUT41762A (en) Process for producing thieno-benzo-pyranes, -thiopyranes and naphtothiophenes and pharmaceutical compositions containing them
PT82960A (en) Process for preparing 5-substituted-6-amino-pyrimidine derivatives and pharmaceutical compositions containing them
GR862249B (en) Dihydropyridin-2-hydroxyamine process for their preparation and their use as medicaments
IL79003A0 (en) Tetrahydroimidazoquinazolinones and pharmaceutical compositions containing them
GR870093B (en) 8a- acylaminoergolines their production and pharmaceutical compositions containing them
IL79980A0 (en) Pharmaceutical composition containing ypsilon-interferon
PT83261A (en) Process for the preparation of new bbm-1675c and d antitumor a ntibiotics and of pharmaceutical compositions containing the same
PT83231A (en) Process for the preparation of gem-dihalo-1,8-diamino-4-aza-octanes and of pharmaceutical compositions containing the same
PT81759B (en) Process for the preparation of 8-alpha-acylamino ergolines and of pharmaceutical compositions containing them
IL74667A (en) Spiro-oxazolidones,-thiazolidones and-imidazolidones and pharmaceutical compositions containing them