ZA862139B - N,n'-dialkylguanidino dipeptide derivatives - Google Patents
N,n'-dialkylguanidino dipeptide derivativesInfo
- Publication number
- ZA862139B ZA862139B ZA862139A ZA862139A ZA862139B ZA 862139 B ZA862139 B ZA 862139B ZA 862139 A ZA862139 A ZA 862139A ZA 862139 A ZA862139 A ZA 862139A ZA 862139 B ZA862139 B ZA 862139B
- Authority
- ZA
- South Africa
- Prior art keywords
- dialkylguanidino
- dipeptide derivatives
- dipeptide
- derivatives
- dialkylguanidino dipeptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pyrrole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71476785A | 1985-03-22 | 1985-03-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA862139B true ZA862139B (en) | 1987-11-25 |
Family
ID=24871369
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA862139A ZA862139B (en) | 1985-03-22 | 1986-03-21 | N,n'-dialkylguanidino dipeptide derivatives |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0196841A1 (es) |
JP (1) | JPS61227594A (es) |
KR (1) | KR860007287A (es) |
CN (1) | CN86101850A (es) |
AU (1) | AU5502386A (es) |
DD (1) | DD243932A5 (es) |
DK (1) | DK133686A (es) |
ES (2) | ES8801930A1 (es) |
FI (1) | FI861210A (es) |
GR (1) | GR860755B (es) |
HU (1) | HUT40143A (es) |
IL (1) | IL78219A0 (es) |
NO (1) | NO861141L (es) |
PT (1) | PT82250B (es) |
ZA (1) | ZA862139B (es) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3413710A1 (de) * | 1984-04-12 | 1985-10-24 | Hoechst Ag, 6230 Frankfurt | Verfahren zur behandlung der herzinsuffizienz |
US5684016A (en) * | 1984-04-12 | 1997-11-04 | Hoechst Aktiengesellschaft | Method of treating cardiac insufficiency |
US5231080A (en) * | 1985-10-15 | 1993-07-27 | Hoechst Aktiengesellschaft | Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease |
US5231084A (en) * | 1986-03-27 | 1993-07-27 | Hoechst Aktiengesellschaft | Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons |
HU203221B (en) * | 1986-09-10 | 1991-06-28 | Syntex Inc | Process for selective amidation of diamines |
US5948939A (en) * | 1986-09-10 | 1999-09-07 | Syntex (U.S.A.) Inc. | Selective amidination of diamines |
US4876359A (en) * | 1986-10-07 | 1989-10-24 | Ss Pharmaceutical Co., Ltd. | Novel gamma-butyrolactone derivatives |
DE3803225A1 (de) * | 1988-02-04 | 1989-08-17 | Hoechst Ag | Aminosaeureamide mit psychotroper wirkung, verfahren zu ihrer herstellung, sie enthaltende mittel und deren verwendung |
US5318992A (en) * | 1990-02-26 | 1994-06-07 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of nitric oxide biosynthesis |
AU636713B2 (en) * | 1990-02-26 | 1993-05-06 | Merrell Dow Pharmaceuticals Inc. | Inhibitors of nitric oxide biosynthesis |
US5710324A (en) * | 1990-02-26 | 1998-01-20 | Merrell Pharmaceuticals Inc. | Inhibitors of nitric oxide biosynthesis |
US5192773A (en) * | 1990-07-02 | 1993-03-09 | Vertex Pharmaceuticals, Inc. | Immunosuppressive compounds |
US5543423A (en) * | 1994-11-16 | 1996-08-06 | Vertex Pharmaceuticals, Incorporated | Amino acid derivatives with improved multi-drug resistance activity |
US5859031A (en) | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
US7056935B2 (en) | 1995-06-07 | 2006-06-06 | Gpi Nil Holdings, Inc. | Rotamase enzyme activity inhibitors |
US5801197A (en) * | 1995-10-31 | 1998-09-01 | Gpi Nil Holdings, Inc. | Rotamase enzyme activity inhibitors |
US5786378A (en) * | 1996-09-25 | 1998-07-28 | Gpi Nil Holdings, Inc. | Heterocyclic thioesters |
US6218424B1 (en) | 1996-09-25 | 2001-04-17 | Gpi Nil Holdings, Inc. | Heterocyclic ketone and thioester compounds and uses |
US5801187A (en) * | 1996-09-25 | 1998-09-01 | Gpi-Nil Holdings, Inc. | Heterocyclic esters and amides |
US5846979A (en) | 1997-02-28 | 1998-12-08 | Gpi Nil Holdings, Inc. | N-oxides of heterocyclic esters, amides, thioesters, and ketones |
US20010049381A1 (en) | 1997-06-04 | 2001-12-06 | Gpl Nil Holdings, Inc., | Pyrrolidine derivative hair growth compositions and uses |
US6274602B1 (en) | 1998-06-03 | 2001-08-14 | Gpi Nil Holdings, Inc. | Heterocyclic thioester and ketone hair growth compositions and uses |
US6271244B1 (en) | 1998-06-03 | 2001-08-07 | Gpi Nil Holdings, Inc. | N-linked urea or carbamate of heterocyclic thioester hair growth compositions and uses |
US6187796B1 (en) | 1998-06-03 | 2001-02-13 | Gpi Nil Holdings, Inc. | Sulfone hair growth compositions and uses |
US5945441A (en) | 1997-06-04 | 1999-08-31 | Gpi Nil Holdings, Inc. | Pyrrolidine carboxylate hair revitalizing agents |
US6187784B1 (en) | 1998-06-03 | 2001-02-13 | Gpi Nil Holdings, Inc. | Pipecolic acid derivative hair growth compositions and uses |
US6429215B1 (en) | 1998-06-03 | 2002-08-06 | Gpi Nil Holdings, Inc. | N-oxide of heterocyclic ester, amide, thioester, or ketone hair growth compositions and uses |
US6331537B1 (en) | 1998-06-03 | 2001-12-18 | Gpi Nil Holdings, Inc. | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds |
EP1085853A1 (en) | 1998-06-03 | 2001-03-28 | GPI NIL Holdings, Inc. | Heterocyclic ester and amide hair growth compositions and uses |
US6172087B1 (en) | 1998-06-03 | 2001-01-09 | Gpi Nil Holding, Inc. | N-oxide of heterocyclic ester, amide, thioester, or ketone hair growth compositions and uses |
US6395758B1 (en) | 1998-08-14 | 2002-05-28 | Gpi Nil Holdings, Inc. | Small molecule carbamates or ureas for vision and memory disorders |
US6399648B1 (en) | 1998-08-14 | 2002-06-04 | Gpi Nil Holdings, Inc. | N-oxides of heterocyclic ester, amide, thioester, or ketone for vision and memory disorders |
US6335348B1 (en) | 1998-08-14 | 2002-01-01 | Gpi Nil Holdings, Inc. | Nitrogen-containing linear and azepinyl/ compositions and uses for vision and memory disorders |
US6218423B1 (en) | 1998-08-14 | 2001-04-17 | Gpi Nil Holdings, Inc. | Pyrrolidine derivatives for vision and memory disorders |
US6337340B1 (en) | 1998-08-14 | 2002-01-08 | Gpi Nil Holdings, Inc. | Carboxylic acids and isosteres of heterocyclic ring compounds having multiple heteroatoms for vision and memory disorders |
US6506788B1 (en) | 1998-08-14 | 2003-01-14 | Gpi Nil Holdings, Inc. | N-linked urea or carbamate of heterocyclic thioesters for vision and memory disorders |
US6333340B1 (en) | 1998-08-14 | 2001-12-25 | Gpi Nil Holdings, Inc. | Small molecule sulfonamides for vision and memory disorders |
US6376517B1 (en) | 1998-08-14 | 2002-04-23 | Gpi Nil Holdings, Inc. | Pipecolic acid derivatives for vision and memory disorders |
US6384056B1 (en) | 1998-08-14 | 2002-05-07 | Gpi Nil Holdings, Inc. | Heterocyclic thioesters or ketones for vision and memory disorders |
US6339101B1 (en) | 1998-08-14 | 2002-01-15 | Gpi Nil Holdings, Inc. | N-linked sulfonamides of N-heterocyclic carboxylic acids or isosteres for vision and memory disorders |
US7338976B1 (en) | 1998-08-14 | 2008-03-04 | Gpi Nil Holdings, Inc. | Heterocyclic esters or amides for vision and memory disorders |
US6462072B1 (en) | 1998-09-21 | 2002-10-08 | Gpi Nil Holdings, Inc. | Cyclic ester or amide derivatives |
US6300341B1 (en) | 1998-09-30 | 2001-10-09 | The Procter & Gamble Co. | 2-substituted heterocyclic sulfonamides |
US6307049B1 (en) | 1998-09-30 | 2001-10-23 | The Procter & Gamble Co. | Heterocyclic 2-substituted ketoamides |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL58849A (en) * | 1978-12-11 | 1983-03-31 | Merck & Co Inc | Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them |
EP0079522B1 (en) * | 1981-11-09 | 1986-05-07 | Merck & Co. Inc. | N-carboxymethyl(amidino)lysyl-proline antihypertensive agents |
-
1986
- 1986-03-19 CN CN198686101850A patent/CN86101850A/zh active Pending
- 1986-03-20 JP JP61064660A patent/JPS61227594A/ja active Pending
- 1986-03-21 EP EP86302111A patent/EP0196841A1/en not_active Withdrawn
- 1986-03-21 DD DD86288166A patent/DD243932A5/de unknown
- 1986-03-21 ES ES553266A patent/ES8801930A1/es not_active Expired
- 1986-03-21 DK DK133686A patent/DK133686A/da not_active Application Discontinuation
- 1986-03-21 PT PT82250A patent/PT82250B/pt unknown
- 1986-03-21 AU AU55023/86A patent/AU5502386A/en not_active Abandoned
- 1986-03-21 IL IL78219A patent/IL78219A0/xx unknown
- 1986-03-21 ZA ZA862139A patent/ZA862139B/xx unknown
- 1986-03-21 GR GR860755A patent/GR860755B/el unknown
- 1986-03-21 HU HU861192A patent/HUT40143A/hu unknown
- 1986-03-21 FI FI861210A patent/FI861210A/fi not_active IP Right Cessation
- 1986-03-21 NO NO861141A patent/NO861141L/no unknown
- 1986-03-22 KR KR1019860002141A patent/KR860007287A/ko not_active Application Discontinuation
-
1988
- 1988-03-30 ES ES557827A patent/ES8900017A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DK133686A (da) | 1986-09-23 |
ES553266A0 (es) | 1988-03-16 |
PT82250A (en) | 1986-04-01 |
DD243932A5 (de) | 1987-03-18 |
KR860007287A (ko) | 1986-10-10 |
AU5502386A (en) | 1986-09-25 |
GR860755B (en) | 1986-05-27 |
EP0196841A1 (en) | 1986-10-08 |
FI861210A (fi) | 1986-09-23 |
ES8801930A1 (es) | 1988-03-16 |
JPS61227594A (ja) | 1986-10-09 |
ES557827A0 (es) | 1988-11-16 |
IL78219A0 (en) | 1986-07-31 |
PT82250B (en) | 1988-01-07 |
HUT40143A (en) | 1986-11-28 |
DK133686D0 (da) | 1986-03-21 |
FI861210A0 (fi) | 1986-03-21 |
CN86101850A (zh) | 1987-02-04 |
NO861141L (no) | 1986-09-23 |
ES8900017A1 (es) | 1988-11-16 |
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