ZA859463B - Sandwich immunoassay - Google Patents
Sandwich immunoassayInfo
- Publication number
- ZA859463B ZA859463B ZA859463A ZA859463A ZA859463B ZA 859463 B ZA859463 B ZA 859463B ZA 859463 A ZA859463 A ZA 859463A ZA 859463 A ZA859463 A ZA 859463A ZA 859463 B ZA859463 B ZA 859463B
- Authority
- ZA
- South Africa
- Prior art keywords
- sandwich immunoassay
- immunoassay
- sandwich
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/539—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
- G01N33/541—Double or second antibody, i.e. precipitating antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/813—Cancer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/822—Identified hapten
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/807—Hapten conjugated with peptide or protein
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/680,730 US4737453A (en) | 1984-12-12 | 1984-12-12 | Sandwich immunoassay utilizing a separation specific binding substance |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA859463B true ZA859463B (en) | 1986-09-24 |
Family
ID=24732276
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA859463A ZA859463B (en) | 1984-12-12 | 1985-12-11 | Sandwich immunoassay |
Country Status (6)
Country | Link |
---|---|
US (1) | US4737453A (ja) |
EP (1) | EP0188093A3 (ja) |
JP (1) | JPS61144573A (ja) |
AU (1) | AU5070785A (ja) |
CA (1) | CA1254828A (ja) |
ZA (1) | ZA859463B (ja) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3685483D1 (de) * | 1985-10-22 | 1992-07-02 | Centocor Inc | Immunometrischer test fuer hochmolekulargewichtiges karzinoembryonisches antigen. |
US5501949A (en) | 1985-12-10 | 1996-03-26 | Murex Diagnostics Corporation | Particle bound binding component immunoassay |
FR2601455B1 (fr) * | 1986-07-11 | 1989-08-04 | Stallergenes Lab | Nouveaux reactifs biologiques en phase solide et leur procede d'obtention |
US5206136A (en) * | 1986-11-19 | 1993-04-27 | Genetic Systems Corporation | Rapid membrane affinity concentration assays |
US5206178A (en) * | 1986-11-19 | 1993-04-27 | Genetic Systems Corporation | Membrane affinity concentration immunoassay |
US4870007A (en) * | 1987-12-18 | 1989-09-26 | Eastman Kodak Company | Immobilized biotinylated receptor in test device, kit and method for determining a ligand |
US5066479A (en) * | 1988-05-31 | 1991-11-19 | The Regents Of The Univ. Of California | Metallacarborane chelates |
US5620845A (en) * | 1988-06-06 | 1997-04-15 | Ampcor, Inc. | Immunoassay diagnostic kit |
DE3834766A1 (de) * | 1988-10-12 | 1990-04-26 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung einer spezifisch bindefaehigen substanz |
SE8804074D0 (sv) * | 1988-11-10 | 1988-11-10 | Pharmacia Ab | Sensorenhet och dess anvaendning i biosensorsystem |
CA2072758A1 (en) * | 1990-09-14 | 1992-03-15 | Kenneth Francis Buechler | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
AU9052491A (en) * | 1990-11-19 | 1992-06-11 | University Of Florida | Assay device and method for antibody and antigen detection |
ATE225512T1 (de) * | 1991-03-20 | 2002-10-15 | Marconi Optical Components Ltd | Abtrennungsverfahren |
GB9125204D0 (en) * | 1991-11-27 | 1992-01-29 | Marconi Gec Ltd | Analysis |
AU3422993A (en) * | 1992-01-06 | 1993-08-03 | Dade International Inc. | Multi-test immunochemical reagent and method to use same |
WO1994003807A1 (en) * | 1992-08-03 | 1994-02-17 | Gec-Marconi Limited | Separation method |
EP0660935B1 (en) * | 1992-08-03 | 2000-05-24 | Gec-Marconi Limited | Immunological detection using two detectable labels |
WO1994012878A1 (en) * | 1992-11-27 | 1994-06-09 | Gec-Marconi Limited | Separation method |
JPH07209299A (ja) * | 1994-01-05 | 1995-08-11 | Channa Shalittin | 良性及び悪性腫瘍の検出のための新規抗体の使用方法 |
AU6720096A (en) | 1995-08-09 | 1997-03-05 | Quidel Corporation | Test strip and method for one step lateral flow assay |
FR2742662B1 (fr) * | 1995-12-21 | 1998-01-23 | Centre Nat Rech Scient | Anticorps anti-idiotypiques du facteur de croissance endotheliale vasculaire et leur utilisation comme medicaments |
US5888757A (en) * | 1996-05-03 | 1999-03-30 | Millennium Pharmaceuticals, Inc. | Cell wall assay |
US5795784A (en) | 1996-09-19 | 1998-08-18 | Abbott Laboratories | Method of performing a process for determining an item of interest in a sample |
US5856194A (en) | 1996-09-19 | 1999-01-05 | Abbott Laboratories | Method for determination of item of interest in a sample |
DE69831229T2 (de) * | 1997-05-14 | 2006-04-13 | Biosite Diagnostics Inc., San Diego | Schnelle bestimmung des verhältnisses von biologischen molekülen |
CA2303123C (en) | 1997-09-22 | 2006-04-11 | Chiron Corporation | Method for detecting antibodies in a sample |
JP4427182B2 (ja) | 1997-09-22 | 2010-03-03 | ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド | 抗原を安定化するための緩衝液 |
WO2003070984A1 (en) * | 2002-02-15 | 2003-08-28 | Somalogic, Inc. | Methods and reagents for detecting target binding by nucleic acid ligands |
US6242246B1 (en) * | 1997-12-15 | 2001-06-05 | Somalogic, Inc. | Nucleic acid ligand diagnostic Biochip |
US20070166741A1 (en) * | 1998-12-14 | 2007-07-19 | Somalogic, Incorporated | Multiplexed analyses of test samples |
US6962702B2 (en) * | 1998-06-22 | 2005-11-08 | Immunomedics Inc. | Production and use of novel peptide-based agents for use with bi-specific antibodies |
US7138103B2 (en) * | 1998-06-22 | 2006-11-21 | Immunomedics, Inc. | Use of bi-specific antibodies for pre-targeting diagnosis and therapy |
US7833528B2 (en) * | 1998-06-22 | 2010-11-16 | Immunomedics, Inc. | Use of multispecific, non-covalent complexes for targeted delivery of therapeutics |
US7405320B2 (en) | 1998-06-22 | 2008-07-29 | Immunomedics, Inc. | Therapeutic and diagnostic conjugates for use with multispecific antibodies |
US7387772B1 (en) * | 1999-06-22 | 2008-06-17 | Immunimedics, Inc. | Chimeric, human and humanized anti-CSAP monoclonal antibodies |
DK1698901T3 (da) * | 1999-01-29 | 2008-12-08 | Roche Diagnostics Gmbh | Metode til at detektere N-terminalt proBNP |
CA2328356A1 (en) | 1999-12-22 | 2001-06-22 | Itty Atcravi | Recreational vehicles |
US7645743B2 (en) * | 1999-12-22 | 2010-01-12 | Altermune, Llc | Chemically programmable immunity |
EP1604183B1 (en) * | 2002-12-26 | 2012-08-29 | Meso Scale Technologies, LLC. | Methods for biomarker extraction |
US20050069958A1 (en) * | 2003-09-26 | 2005-03-31 | Mills Rhonda A. | Method for simultaneous evaluation of a sample containing a cellular target and a soluble analyte |
US20060024744A1 (en) * | 2004-07-28 | 2006-02-02 | Mills Rhonda A | Methods for substantially simultaneous evaluation of a sample containing a cellular target and a soluble analyte |
US20060046310A1 (en) * | 2004-08-25 | 2006-03-02 | Zong-Li Xia | Amplification method for solid phase immunoassays |
HUE025489T2 (en) * | 2006-01-17 | 2016-04-28 | Somalogic Inc | Multiplexed analysis of test samples |
US8975026B2 (en) | 2007-01-16 | 2015-03-10 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
US7947447B2 (en) | 2007-01-16 | 2011-05-24 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
US20110136099A1 (en) * | 2007-01-16 | 2011-06-09 | Somalogic, Inc. | Multiplexed Analyses of Test Samples |
US7855054B2 (en) * | 2007-01-16 | 2010-12-21 | Somalogic, Inc. | Multiplexed analyses of test samples |
US7964356B2 (en) * | 2007-01-16 | 2011-06-21 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
CN101627306B (zh) * | 2007-03-08 | 2014-02-05 | 霍夫曼-拉罗奇有限公司 | Slim-1在心力衰竭评估中的用途 |
US8906700B2 (en) | 2007-11-06 | 2014-12-09 | Ambergen, Inc. | Methods and compositions for phototransfer |
US8703416B2 (en) | 2008-07-17 | 2014-04-22 | Somalogic, Inc. | Method for purification and identification of sperm cells |
WO2010129666A1 (en) | 2009-05-05 | 2010-11-11 | Altermune Technologies, Llc | Chemically programmable immunity |
EP2542266A4 (en) | 2010-03-03 | 2013-10-23 | Somalogic Inc | 4-1BB-BINDING APTAMERS AND USE THEREOF IN THE TREATMENT OF DISEASES AND DISORDERS |
JP6012591B2 (ja) | 2010-04-12 | 2016-10-26 | ソマロジック, インコーポレイテッドSomaLogic, Inc. | β−NGFに対するアプタマー及びβ−NGF介在疾患及び障害の治療におけるその使用 |
EP2817423B1 (en) * | 2012-02-21 | 2017-05-31 | Laboratory Corporation of America Holdings | Methods and systems for signal amplification of bioassays |
US9410156B2 (en) | 2012-03-28 | 2016-08-09 | Somalogic, Inc. | Aptamers to PDGF and VEGF and their use in treating PDGF and VEGF mediated conditions |
CA2920508C (en) | 2013-09-09 | 2024-01-16 | Somalogic, Inc. | Pdgf and vegf aptamers having improved stability and their use in treating pdgf and vegf mediated diseases and disorders |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7501215A (nl) * | 1975-02-01 | 1976-08-03 | Akzo Nv | Methode voor het aantonen en bepalen van een antigeen of antilichaam. |
US4098876A (en) * | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
US4134792A (en) * | 1976-12-06 | 1979-01-16 | Miles Laboratories, Inc. | Specific binding assay with an enzyme modulator as a labeling substance |
US4271140A (en) * | 1978-01-23 | 1981-06-02 | Baxter Travenol Laboratories, Inc. | Method and composition for double receptor, specific binding assays |
JPS5510590A (en) * | 1978-05-04 | 1980-01-25 | Wellcome Found | Enzyme immunity quantity analysis |
US4189464A (en) * | 1978-05-05 | 1980-02-19 | Institute For Cancer Research | Hepatitis B testing reagent and method |
US4230683A (en) * | 1978-08-09 | 1980-10-28 | Abbott Laboratories | Hapten conjugated antibody for antibody or antigen detection |
US4371515A (en) * | 1978-12-26 | 1983-02-01 | E-Y Laboratories, Inc. | Method for forming an isolated lectin-immunological conjugate |
US4289747A (en) * | 1978-12-26 | 1981-09-15 | E-Y Laboratories, Inc. | Immunological determination using lectin |
GB2084317B (en) * | 1980-09-30 | 1984-01-18 | Erba Farmitalia | Antigen-linked competitive enzymeimmunoassay |
GB2098730B (en) * | 1981-04-21 | 1985-02-06 | Welsh Nat School Med | Immunolocalisation |
US4478946A (en) * | 1981-07-02 | 1984-10-23 | South African Inventions Development Corporation | Carrier bound immunosorbent |
US4471058A (en) * | 1982-07-26 | 1984-09-11 | Board Of Trustees Operating Michigan State University | Method for the detection and/or determination of a polyvalent antigen using at least two different monoclonal antibodies |
DE3377531D1 (en) * | 1982-09-29 | 1988-09-01 | Serono Diagnostics Ltd | Immunoassay of antigens |
US4496654A (en) * | 1983-04-08 | 1985-01-29 | Quidel | Detection of HCG with solid phase support having avidin coating |
FR2549230B1 (fr) * | 1983-06-14 | 1986-04-11 | Bio Merieux | Procede de detection d'un oligomere dans un milieu liquide contenant des monomeres correspondants, dispositif pour la mise en oeuvre de ce procede et application notamment a la recherche d'allergenes |
-
1984
- 1984-12-12 US US06/680,730 patent/US4737453A/en not_active Expired - Fee Related
-
1985
- 1985-11-01 JP JP60246122A patent/JPS61144573A/ja active Pending
- 1985-11-21 CA CA000495894A patent/CA1254828A/en not_active Expired
- 1985-12-03 AU AU50707/85A patent/AU5070785A/en not_active Abandoned
- 1985-12-11 ZA ZA859463A patent/ZA859463B/xx unknown
- 1985-12-12 EP EP85309043A patent/EP0188093A3/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP0188093A2 (en) | 1986-07-23 |
US4737453A (en) | 1988-04-12 |
EP0188093A3 (en) | 1987-09-30 |
JPS61144573A (ja) | 1986-07-02 |
AU5070785A (en) | 1986-06-19 |
CA1254828A (en) | 1989-05-30 |
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