ZA857059B - New an imidazole group containing 3,4-dihydro-2(1h)-pyridones and 2(1h)-pyridones,processes for their preparation and pharmaceutical preparations containing them - Google Patents
New an imidazole group containing 3,4-dihydro-2(1h)-pyridones and 2(1h)-pyridones,processes for their preparation and pharmaceutical preparations containing themInfo
- Publication number
- ZA857059B ZA857059B ZA857059A ZA857059A ZA857059B ZA 857059 B ZA857059 B ZA 857059B ZA 857059 A ZA857059 A ZA 857059A ZA 857059 A ZA857059 A ZA 857059A ZA 857059 B ZA857059 B ZA 857059B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyridones
- new
- dihydro
- processes
- preparation
- Prior art date
Links
- 125000002883 imidazolyl group Chemical group 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- ZPOODPZCZLCUAN-UHFFFAOYSA-N 3,4-dihydro-1h-pyridin-2-one Chemical class O=C1CCC=CN1 ZPOODPZCZLCUAN-UHFFFAOYSA-N 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Liquid Crystal Substances (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843433953 DE3433953A1 (de) | 1984-09-15 | 1984-09-15 | Neue, eine imidazol-gruppe enthaltende 3,4-dihydro-2(1h)-pyridone und2(1h)-pyridone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA857059B true ZA857059B (en) | 1986-04-30 |
Family
ID=6245507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA857059A ZA857059B (en) | 1984-09-15 | 1985-09-13 | New an imidazole group containing 3,4-dihydro-2(1h)-pyridones and 2(1h)-pyridones,processes for their preparation and pharmaceutical preparations containing them |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4699914A (OSRAM) |
| EP (1) | EP0175187B1 (OSRAM) |
| JP (1) | JPS6172781A (OSRAM) |
| AT (1) | ATE49408T1 (OSRAM) |
| DE (2) | DE3433953A1 (OSRAM) |
| DK (1) | DK417785A (OSRAM) |
| ES (2) | ES8705424A1 (OSRAM) |
| GR (1) | GR852181B (OSRAM) |
| PT (1) | PT81128B (OSRAM) |
| ZA (1) | ZA857059B (OSRAM) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743608A (en) * | 1986-07-15 | 1988-05-10 | Rorer Pharmaceutical Corporation | Pyridone-pyridyl-imidazolyl and triazolyl compounds and their use as cardiotonic agents |
| US4708958A (en) * | 1986-09-24 | 1987-11-24 | G. D. Searle & Co. | 6-(imidazolyphenyl)-4-iminopyrimidinones useful as hypotensive agents |
| US4737511A (en) * | 1986-11-03 | 1988-04-12 | Schering A.G. | Cardiotonic imidazolylphenylpyrrol-2-ones |
| US6001835A (en) * | 1996-04-03 | 1999-12-14 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| JP2000507585A (ja) * | 1996-04-03 | 2000-06-20 | メルク エンド カンパニー インコーポレーテッド | ファルネシルタンパク質トランスフェラーゼの阻害剤 |
| DE19627310A1 (de) * | 1996-06-27 | 1998-01-02 | Schering Ag | Imidazolderivate als Stickstoffmonoxid-Synthase-Inhibitoren |
| KR100388790B1 (ko) * | 1998-03-06 | 2003-10-04 | 주식회사 엘지생명과학 | 파네실전이효소저해제로서유용한피리딘-2-온유도체 |
| PE20060285A1 (es) * | 2004-03-30 | 2006-05-08 | Aventis Pharma Inc | Piridonas sustituidas como inhibidores de pol(adp-ribosa)-polimerasa (parp) |
| TW200635587A (en) * | 2004-12-01 | 2006-10-16 | Kalypsys Inc | Inducible nitric oxide synthase dimerization inhibitors |
| BRPI0620526A2 (pt) * | 2005-11-28 | 2011-11-16 | Kalypsys Inc | sal de acetato e método para alcançar um efeito em um paciente |
| CA2874953A1 (en) * | 2012-06-12 | 2013-12-19 | Abbvie Inc. | Pyridinone and pyridazinone derivatives |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE790106A (fr) * | 1971-10-14 | 1973-04-13 | Basf Ag | Dihydropyridazones, leur preparation et leurs utilisations therapeutiques |
| DE3016874A1 (de) * | 1980-05-02 | 1981-11-05 | Bayer Ag, 5090 Leverkusen | Substituierte 2-amino-3,4-dihydropyridinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US4503061A (en) * | 1983-07-22 | 1985-03-05 | Warner-Lambert Company | Substituted phenyl-pyridinones as cardiotonic agents |
| IL69407A (en) * | 1982-08-23 | 1987-10-20 | Warner Lambert Co | 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them |
| IL70169A0 (en) * | 1982-11-18 | 1984-02-29 | Sterling Drug Inc | 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them |
-
1984
- 1984-09-15 DE DE19843433953 patent/DE3433953A1/de not_active Withdrawn
-
1985
- 1985-08-29 DE DE8585110906T patent/DE3575300D1/de not_active Expired - Lifetime
- 1985-08-29 AT AT85110906T patent/ATE49408T1/de not_active IP Right Cessation
- 1985-08-29 EP EP85110906A patent/EP0175187B1/de not_active Expired - Lifetime
- 1985-09-03 US US06/771,984 patent/US4699914A/en not_active Expired - Fee Related
- 1985-09-09 GR GR852181A patent/GR852181B/el unknown
- 1985-09-13 DK DK417785A patent/DK417785A/da not_active Application Discontinuation
- 1985-09-13 ES ES546965A patent/ES8705424A1/es not_active Expired
- 1985-09-13 ZA ZA857059A patent/ZA857059B/xx unknown
- 1985-09-13 PT PT81128A patent/PT81128B/pt not_active IP Right Cessation
- 1985-09-13 JP JP60201950A patent/JPS6172781A/ja active Pending
-
1986
- 1986-05-03 ES ES554634A patent/ES8704927A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6172781A (ja) | 1986-04-14 |
| GR852181B (OSRAM) | 1986-01-10 |
| DE3575300D1 (de) | 1990-02-15 |
| DE3433953A1 (de) | 1986-03-27 |
| ES8705424A1 (es) | 1987-05-01 |
| ATE49408T1 (de) | 1990-01-15 |
| DK417785A (da) | 1986-03-16 |
| US4699914A (en) | 1987-10-13 |
| ES8704927A1 (es) | 1987-04-16 |
| EP0175187B1 (de) | 1990-01-10 |
| PT81128B (pt) | 1987-10-20 |
| PT81128A (en) | 1985-10-01 |
| DK417785D0 (da) | 1985-09-13 |
| ES546965A0 (es) | 1987-05-01 |
| ES554634A0 (es) | 1987-04-16 |
| EP0175187A1 (de) | 1986-03-26 |
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