PT81128B - Processo para a preparacao de novas 3,4-dihidro-2(1h)-piridonas e 2(1h)-piridonas contendo um grupo imidazole e de composicoes farmaceuticas que as contem - Google Patents

Processo para a preparacao de novas 3,4-dihidro-2(1h)-piridonas e 2(1h)-piridonas contendo um grupo imidazole e de composicoes farmaceuticas que as contem

Info

Publication number
PT81128B
PT81128B PT81128A PT8112885A PT81128B PT 81128 B PT81128 B PT 81128B PT 81128 A PT81128 A PT 81128A PT 8112885 A PT8112885 A PT 8112885A PT 81128 B PT81128 B PT 81128B
Authority
PT
Portugal
Prior art keywords
pyridones
new
imidazole
dihydro
preparation
Prior art date
Application number
PT81128A
Other languages
English (en)
Other versions
PT81128A (en
Inventor
Gerd Hilboll
Ille-Stephanie Doppelfeld
Gerrit Prop
Original Assignee
Nattermann A & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nattermann A & Cie filed Critical Nattermann A & Cie
Publication of PT81128A publication Critical patent/PT81128A/pt
Publication of PT81128B publication Critical patent/PT81128B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT81128A 1984-09-15 1985-09-13 Processo para a preparacao de novas 3,4-dihidro-2(1h)-piridonas e 2(1h)-piridonas contendo um grupo imidazole e de composicoes farmaceuticas que as contem PT81128B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843433953 DE3433953A1 (de) 1984-09-15 1984-09-15 Neue, eine imidazol-gruppe enthaltende 3,4-dihydro-2(1h)-pyridone und2(1h)-pyridone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
PT81128A PT81128A (en) 1985-10-01
PT81128B true PT81128B (pt) 1987-10-20

Family

ID=6245507

Family Applications (1)

Application Number Title Priority Date Filing Date
PT81128A PT81128B (pt) 1984-09-15 1985-09-13 Processo para a preparacao de novas 3,4-dihidro-2(1h)-piridonas e 2(1h)-piridonas contendo um grupo imidazole e de composicoes farmaceuticas que as contem

Country Status (10)

Country Link
US (1) US4699914A (pt)
EP (1) EP0175187B1 (pt)
JP (1) JPS6172781A (pt)
AT (1) ATE49408T1 (pt)
DE (2) DE3433953A1 (pt)
DK (1) DK417785A (pt)
ES (2) ES8705424A1 (pt)
GR (1) GR852181B (pt)
PT (1) PT81128B (pt)
ZA (1) ZA857059B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743608A (en) * 1986-07-15 1988-05-10 Rorer Pharmaceutical Corporation Pyridone-pyridyl-imidazolyl and triazolyl compounds and their use as cardiotonic agents
US4708958A (en) * 1986-09-24 1987-11-24 G. D. Searle & Co. 6-(imidazolyphenyl)-4-iminopyrimidinones useful as hypotensive agents
US4737511A (en) * 1986-11-03 1988-04-12 Schering A.G. Cardiotonic imidazolylphenylpyrrol-2-ones
CA2250353A1 (en) * 1996-04-03 1997-10-09 Christopher J. Dinsmore Inhibitors of farnesyl-protein transferase
US6001835A (en) * 1996-04-03 1999-12-14 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
DE19627310A1 (de) * 1996-06-27 1998-01-02 Schering Ag Imidazolderivate als Stickstoffmonoxid-Synthase-Inhibitoren
KR100388790B1 (ko) * 1998-03-06 2003-10-04 주식회사 엘지생명과학 파네실전이효소저해제로서유용한피리딘-2-온유도체
PE20060285A1 (es) * 2004-03-30 2006-05-08 Aventis Pharma Inc Piridonas sustituidas como inhibidores de pol(adp-ribosa)-polimerasa (parp)
JP2008521908A (ja) * 2004-12-01 2008-06-26 カリプシス・インコーポレーテッド 誘導型一酸化窒素シンターゼ阻害剤
JP2009517483A (ja) * 2005-11-28 2009-04-30 カリプシス・インコーポレーテッド 一酸化窒素シンターゼの二量化の抑制剤としてのイミダゾール誘導体
SG11201408324QA (en) 2012-06-12 2015-01-29 Abbvie Inc Pyridinone and pyridazinone derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE790106A (fr) * 1971-10-14 1973-04-13 Basf Ag Dihydropyridazones, leur preparation et leurs utilisations therapeutiques
DE3016874A1 (de) * 1980-05-02 1981-11-05 Bayer Ag, 5090 Leverkusen Substituierte 2-amino-3,4-dihydropyridinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
IL69407A (en) * 1982-08-23 1987-10-20 Warner Lambert Co 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them
US4503061A (en) * 1983-07-22 1985-03-05 Warner-Lambert Company Substituted phenyl-pyridinones as cardiotonic agents
IL70169A0 (en) * 1982-11-18 1984-02-29 Sterling Drug Inc 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JPS6172781A (ja) 1986-04-14
ATE49408T1 (de) 1990-01-15
ZA857059B (en) 1986-04-30
US4699914A (en) 1987-10-13
GR852181B (pt) 1986-01-10
ES8705424A1 (es) 1987-05-01
ES8704927A1 (es) 1987-04-16
EP0175187A1 (de) 1986-03-26
DE3433953A1 (de) 1986-03-27
ES546965A0 (es) 1987-05-01
DK417785D0 (da) 1985-09-13
DE3575300D1 (de) 1990-02-15
ES554634A0 (es) 1987-04-16
EP0175187B1 (de) 1990-01-10
PT81128A (en) 1985-10-01
DK417785A (da) 1986-03-16

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