ZA855280B - 1-6-naphthyridin-2(1h)-ones useful as cardiotonics - Google Patents
1-6-naphthyridin-2(1h)-ones useful as cardiotonicsInfo
- Publication number
- ZA855280B ZA855280B ZA855280A ZA855280A ZA855280B ZA 855280 B ZA855280 B ZA 855280B ZA 855280 A ZA855280 A ZA 855280A ZA 855280 A ZA855280 A ZA 855280A ZA 855280 B ZA855280 B ZA 855280B
- Authority
- ZA
- South Africa
- Prior art keywords
- cardiotonics
- naphthyridin
- ones useful
- ones
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/630,810 US4560691A (en) | 1984-07-13 | 1984-07-13 | 5-(Phenyl)-1,6-naphthyridin-2(1H)-ones, their cardiotonic use and preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA855280B true ZA855280B (en) | 1986-02-26 |
Family
ID=24528649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA855280A ZA855280B (en) | 1984-07-13 | 1985-07-12 | 1-6-naphthyridin-2(1h)-ones useful as cardiotonics |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4560691A (OSRAM) |
| EP (1) | EP0168037B1 (OSRAM) |
| JP (1) | JPS6140286A (OSRAM) |
| KR (1) | KR870001089B1 (OSRAM) |
| AR (1) | AR242388A1 (OSRAM) |
| AT (1) | ATE50259T1 (OSRAM) |
| AU (1) | AU584103B2 (OSRAM) |
| DE (1) | DE3575926D1 (OSRAM) |
| DK (1) | DK318985A (OSRAM) |
| ES (1) | ES8706151A1 (OSRAM) |
| FI (1) | FI852765A7 (OSRAM) |
| GR (1) | GR851677B (OSRAM) |
| IL (1) | IL75733A (OSRAM) |
| MX (1) | MX161361A (OSRAM) |
| NO (1) | NO852677L (OSRAM) |
| NZ (1) | NZ212647A (OSRAM) |
| PH (1) | PH21844A (OSRAM) |
| PT (1) | PT80809B (OSRAM) |
| ZA (1) | ZA855280B (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4532247A (en) * | 1983-08-08 | 1985-07-30 | Sterling Drug Inc. | 5-(Hydroxyalkyl or alkanoyloxymethyl)-1,6-naphthyridin-2(1H)-one and cardiotonic use thereof |
| US4567186A (en) * | 1985-01-14 | 1986-01-28 | Sterling Drug Inc. | 5-Heteryl-1,6-naphthyridin-2(1H)-ones, cardiotonic use thereof and intermediates therefor |
| NZ214837A (en) * | 1985-01-28 | 1988-10-28 | Sterling Drug Inc | 5-substituted 1,6 naphthyridin-2(1h)-ones |
| DE3840341A1 (de) * | 1988-11-30 | 1990-06-07 | Basf Ag | Verfahren zur herstellung von 1-nitroanthrachinon-2-carbonsaeure |
| US7235551B2 (en) * | 2000-03-02 | 2007-06-26 | Smithkline Beecham Corporation | 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases |
| DK1333833T3 (da) * | 2000-10-23 | 2011-12-12 | Glaxosmithkline Llc | Ny trisubstitueret 8H-pyridol[2,3-d]pyrimidin-7-on-forbindelse til behandling af CSBP/RK/p38-kinnasemedierede sygdomme |
| AU2003225072A1 (en) * | 2002-04-19 | 2003-11-03 | Smithkline Beecham Corporation | Novel compounds |
| CA2515939A1 (en) * | 2003-02-14 | 2004-09-02 | Smithkline Beecham Corporation | Novel compounds |
| TWI389690B (zh) * | 2005-03-25 | 2013-03-21 | Glaxo Group Ltd | 新穎化合物（一） |
| CA2603163A1 (en) * | 2005-03-25 | 2006-10-05 | Glaxo Group Limited | Process for preparing pyrido[2,3-d]pyrimidin-7-one and 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1h)-one derivatives |
| WO2006110298A2 (en) * | 2005-03-25 | 2006-10-19 | Glaxo Group Limited | 8-alkyl/aryl-4-aryl-2-n- (alkylamino)-n'-substituted-n'-cyanoguanidino-8h-pyrido[2,3-d]pyrimidin-7-one compounds and use thereof |
| PE20061193A1 (es) * | 2005-03-25 | 2006-12-02 | Glaxo Group Ltd | DERIVADOS DE 3,4-DIHIDROPIRIMIDO[4,5-d]PIRIMIDIN-2-[1H]-0NA COMO INHIBIDORES DE QUINASA p38 |
| CN105218388B (zh) * | 2015-10-26 | 2017-07-11 | 西北农林科技大学 | β‑羰基烯胺类化合物及作为制备植物病原菌抗菌剂的应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4412077A (en) * | 1982-03-15 | 1983-10-25 | Sterling Drug Inc. | Process for preparing 5-(lower-alkanoyl)-6-(lower-alkyl)-2(1H)-pyridinone |
| US4415580A (en) * | 1982-08-02 | 1983-11-15 | Sterling Drug Inc. | Certain 2-(1H)-pyridinones cardiotonic compositions containing same and method of using same |
-
1984
- 1984-07-13 US US06/630,810 patent/US4560691A/en not_active Expired - Fee Related
-
1985
- 1985-07-03 NO NO852677A patent/NO852677L/no unknown
- 1985-07-04 NZ NZ212647A patent/NZ212647A/xx unknown
- 1985-07-05 GR GR851677A patent/GR851677B/el unknown
- 1985-07-05 IL IL75733A patent/IL75733A/xx unknown
- 1985-07-09 AT AT85108538T patent/ATE50259T1/de not_active IP Right Cessation
- 1985-07-09 DE DE8585108538T patent/DE3575926D1/de not_active Expired - Fee Related
- 1985-07-09 EP EP85108538A patent/EP0168037B1/en not_active Expired - Lifetime
- 1985-07-09 MX MX8266A patent/MX161361A/es unknown
- 1985-07-10 AU AU44747/85A patent/AU584103B2/en not_active Ceased
- 1985-07-10 JP JP15215885A patent/JPS6140286A/ja active Pending
- 1985-07-11 PH PH32510A patent/PH21844A/en unknown
- 1985-07-11 AR AR85300954A patent/AR242388A1/es active
- 1985-07-12 ES ES545139A patent/ES8706151A1/es not_active Expired
- 1985-07-12 KR KR1019850004976A patent/KR870001089B1/ko not_active Expired
- 1985-07-12 DK DK318985A patent/DK318985A/da unknown
- 1985-07-12 ZA ZA855280A patent/ZA855280B/xx unknown
- 1985-07-12 PT PT80809A patent/PT80809B/pt unknown
- 1985-07-12 FI FI852765A patent/FI852765A7/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AR242388A1 (es) | 1993-03-31 |
| FI852765L (fi) | 1986-01-14 |
| NZ212647A (en) | 1988-07-28 |
| GR851677B (OSRAM) | 1985-11-26 |
| IL75733A (en) | 1988-07-31 |
| DK318985D0 (da) | 1985-07-12 |
| ATE50259T1 (de) | 1990-02-15 |
| JPS6140286A (ja) | 1986-02-26 |
| EP0168037A2 (en) | 1986-01-15 |
| PT80809B (en) | 1987-01-12 |
| ES545139A0 (es) | 1987-06-01 |
| KR860001109A (ko) | 1986-02-22 |
| FI852765A0 (fi) | 1985-07-12 |
| FI852765A7 (fi) | 1986-01-14 |
| NO852677L (no) | 1986-01-14 |
| PT80809A (en) | 1985-08-01 |
| KR870001089B1 (ko) | 1987-06-04 |
| MX161361A (es) | 1990-09-18 |
| EP0168037A3 (en) | 1986-03-26 |
| AU4474785A (en) | 1986-01-16 |
| IL75733A0 (en) | 1985-11-29 |
| AU584103B2 (en) | 1989-05-18 |
| ES8706151A1 (es) | 1987-06-01 |
| DE3575926D1 (de) | 1990-03-15 |
| PH21844A (en) | 1988-03-17 |
| US4560691A (en) | 1985-12-24 |
| DK318985A (da) | 1986-01-14 |
| EP0168037B1 (en) | 1990-02-07 |
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