ZA855248B - Monoclonal antibody stabilization - Google Patents

Monoclonal antibody stabilization

Info

Publication number
ZA855248B
ZA855248B ZA855248A ZA855248A ZA855248B ZA 855248 B ZA855248 B ZA 855248B ZA 855248 A ZA855248 A ZA 855248A ZA 855248 A ZA855248 A ZA 855248A ZA 855248 B ZA855248 B ZA 855248B
Authority
ZA
South Africa
Prior art keywords
monoclonal antibody
antibody stabilization
stabilization
solution containing
monoclonal antibodies
Prior art date
Application number
ZA855248A
Other languages
English (en)
Inventor
Robert H Dodge
Randall J Avers
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of ZA855248B publication Critical patent/ZA855248B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/825—Pretreatment for removal of interfering factors from sample
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/826—Additives, e.g. buffers, diluents, preservatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA855248A 1984-08-09 1985-07-11 Monoclonal antibody stabilization ZA855248B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/639,156 US4650772A (en) 1984-08-09 1984-08-09 Monoclonal antibody stabilization

Publications (1)

Publication Number Publication Date
ZA855248B true ZA855248B (en) 1986-02-26

Family

ID=24562959

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA855248A ZA855248B (en) 1984-08-09 1985-07-11 Monoclonal antibody stabilization

Country Status (15)

Country Link
US (1) US4650772A (de)
EP (1) EP0170983B1 (de)
JP (1) JPH0699325B2 (de)
KR (1) KR900002652B1 (de)
AT (1) ATE57021T1 (de)
AU (1) AU592952B2 (de)
CA (1) CA1238284A (de)
DE (1) DE3579868D1 (de)
DK (1) DK333185A (de)
ES (1) ES8702790A1 (de)
GR (1) GR851926B (de)
IE (1) IE58626B1 (de)
IL (1) IL75762A (de)
NZ (1) NZ212694A (de)
ZA (1) ZA855248B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ217844A (en) * 1985-10-11 1989-10-27 Sumitomo Pharma A sustained release pharmaceutical composition containing silicone elastomer and an albumin
US5237054A (en) * 1987-02-20 1993-08-17 Akzo Pharma Stabilized aqueous composition containing antibodies
ES2053704T3 (es) * 1987-02-20 1994-08-01 Akzo Nv Un metodo de estabilizacion de una composicion acuosa consistente en uno o mas anticuerpos monoclonales.
DE3825429C2 (de) * 1988-07-27 1994-02-10 Biotest Pharma Gmbh Verfahren zur Herstellung eines intravenös verabreichbaren polyklonalen Immunglobulin-Präparates mit hohem IgM-Gehalt
WO1992001808A1 (en) * 1990-07-18 1992-02-06 Dojin Iyaku-Kako Co., Ltd. Reagent for diagnosing mycoplasma pneumoniae
JP2627681B2 (ja) * 1990-07-18 1997-07-09 同仁医薬化工株式会社 マイコプラズマ・ニューモニエ診断用試薬
JPH0565233A (ja) * 1991-03-08 1993-03-19 Mitsui Toatsu Chem Inc モノクローナル抗体含有凍結乾燥製剤
JP2553445B2 (ja) * 1992-12-17 1996-11-13 同仁医薬化工株式会社 抗体の安定化方法
EP0852951A1 (de) 1996-11-19 1998-07-15 Roche Diagnostics GmbH Stabile lyophilisierte pharmazeutische Zubereitungen von mono- oder polyklonalen Antikörpern
MX2007014148A (es) * 2005-05-19 2008-01-11 Amgen Inc Composiciones y metodos para incrementar la estabilidad de anticuerpos.
EP2529228A4 (de) * 2010-01-26 2013-09-04 Obschestvo S Ogranichennoi Otvetstvennostyu N Proizv Materia Medika Kholding Fa Verfahren zur festlegung eines autoantikörper-pegels mittels eines enzym-immunoassays

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5816471B2 (ja) * 1977-11-29 1983-03-31 持田製薬株式会社 免疫化学的測定試薬の安定化剤
JPS58144748A (ja) * 1982-02-23 1983-08-29 Eiken Kagaku Kk 免疫学的反応用ラテツクス試薬
US4444880A (en) * 1982-07-27 1984-04-24 Syva Company Periodate removal of ascorbate interference in dipsticks for immunoassays
US4439421A (en) * 1982-08-30 1984-03-27 Baxter Travenol Laboratories, Inc. Stabilized gamma globulin concentrate
US4482483A (en) * 1983-04-06 1984-11-13 Armour Pharmceutical Company Composition of intravenous immune globulin

Also Published As

Publication number Publication date
IL75762A (en) 1989-10-31
EP0170983A2 (de) 1986-02-12
ATE57021T1 (de) 1990-10-15
DE3579868D1 (de) 1990-10-31
EP0170983A3 (en) 1988-01-27
KR900002652B1 (ko) 1990-04-21
AU4536985A (en) 1986-02-13
AU592952B2 (en) 1990-02-01
GR851926B (de) 1985-12-09
DK333185D0 (da) 1985-07-22
IE851964L (en) 1986-02-09
US4650772A (en) 1987-03-17
NZ212694A (en) 1988-05-30
JPH0699325B2 (ja) 1994-12-07
IE58626B1 (en) 1993-10-20
EP0170983B1 (de) 1990-09-26
KR860001594A (ko) 1986-03-20
DK333185A (da) 1986-02-10
JPS6176423A (ja) 1986-04-18
CA1238284A (en) 1988-06-21
ES545975A0 (es) 1987-01-16
ES8702790A1 (es) 1987-01-16
IL75762A0 (en) 1985-11-29

Similar Documents

Publication Publication Date Title
ES2059413T3 (es) Anticuerpos monoclonales contra antigenos asociados a melanoma, progenies celulares hibridas que producen estos anticuerpos, y su empleo correspondiente.
CA1262357A (en) N-HYDROXYL PROTECTIVE GROUPS AND METHOD FOR THE PREPARATION OF 3-ACYLAMINO-1-HYDROXY-2-AZETIDINONES
EP0394277A4 (en) Second generation monoclonal antibodies having binding specificity to tag-72 and human carcinomas and methods for employing the same
GB8428321D0 (en) Production of antibodies
EP0236987A3 (en) Chemically modified protein and production thereof
IL58016A0 (en) Synthesis of a eucaryotic protein by a microorganism
IT8120700A0 (it) Produzione dell'ormone bovino della crescita mediante microorganismi.
ZA855248B (en) Monoclonal antibody stabilization
GB2086937B (en) Production of human monoclonal antibodies by human hybridomas
DE3684211D1 (de)
GR79567B (de)
PT85490A (en) Process for the preparation of specific monoclonal antibodies of apolipoprotein-b and essay processes for the determination o the above mentioned apolipoprotein
JPS57200493A (en) Manufacture of pumpable coal-water suspension
EP0303088A3 (en) Purified igm
ES481882A1 (es) Un procedimiento para la preparacion de acido 6-cloro-alfa- metilcarbazol-2-acetico.
ES8302724A1 (es) Procedimiento de preparacion de alcoxiaminohidridosilanos.
GB8727030D0 (en) Production of monoclonal antibodies
ES8603476A1 (es) Procedimiento para preparar 2-imino-3, 4, 6, 7-tetrahidro-4h-pirimido (6, 1-a) isoquinolin-4-onas sustituidas
GB2087892B (en) Stereoselective synthesis of 3-amino-20-oxygenated-5a-pregnanes via novel pregn-17(20)-ene intermediates
ES8609203A1 (es) Un procedimiento para preparar 1,5,10-triazadecanos susti- tuidos en posicion 5
JPS5774091A (en) Preparation of l-aspartic acid by fixed microorganism
KR790000259B1 (en) Production of n-ciano-n'-methyl-n"-(2-(5-methyl-4-imidazolyl)methylthio)ethyl)guanidine
DE3165192D1 (en) Process for the preparation of synthesis gas
DE3461189D1 (en) New 3-alkylthio-2-o-carbamoyl-propane-1.2-diol-1-o-phosphocholines, and processes for their preparation
GB8705550D0 (en) Monoclonal antibodies to urokinase