ES2053704T3 - Un metodo de estabilizacion de una composicion acuosa consistente en uno o mas anticuerpos monoclonales. - Google Patents

Un metodo de estabilizacion de una composicion acuosa consistente en uno o mas anticuerpos monoclonales.

Info

Publication number
ES2053704T3
ES2053704T3 ES88200264T ES88200264T ES2053704T3 ES 2053704 T3 ES2053704 T3 ES 2053704T3 ES 88200264 T ES88200264 T ES 88200264T ES 88200264 T ES88200264 T ES 88200264T ES 2053704 T3 ES2053704 T3 ES 2053704T3
Authority
ES
Spain
Prior art keywords
aqueous composition
monoclonal antibodies
composition consisting
stabilization method
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88200264T
Other languages
English (en)
Inventor
Gerrit Johannes Brinks
Maria Martina Francisc Mentink
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Application granted granted Critical
Publication of ES2053704T3 publication Critical patent/ES2053704T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UNA COMPOSICION ACUOSA ESTABILIZADA QUE CONTIENE UNO O MAS ANTICUERPOS Y DEXTRANO.
ES88200264T 1987-02-20 1988-02-15 Un metodo de estabilizacion de una composicion acuosa consistente en uno o mas anticuerpos monoclonales. Expired - Lifetime ES2053704T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8700422 1987-02-20

Publications (1)

Publication Number Publication Date
ES2053704T3 true ES2053704T3 (es) 1994-08-01

Family

ID=19849604

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88200264T Expired - Lifetime ES2053704T3 (es) 1987-02-20 1988-02-15 Un metodo de estabilizacion de una composicion acuosa consistente en uno o mas anticuerpos monoclonales.

Country Status (6)

Country Link
EP (1) EP0280358B1 (es)
JP (1) JP2655667B2 (es)
AT (1) ATE83930T1 (es)
DE (1) DE3877015T2 (es)
ES (1) ES2053704T3 (es)
GR (1) GR3007486T3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6165467A (en) * 1991-07-20 2000-12-26 Yoshihide Hagiwara Stabilized human monoclonal antibody preparation
EP0852951A1 (de) 1996-11-19 1998-07-15 Roche Diagnostics GmbH Stabile lyophilisierte pharmazeutische Zubereitungen von mono- oder polyklonalen Antikörpern
ATE479490T1 (de) * 2001-10-11 2010-09-15 Aviva Biosciences Corp Verfahren zum trennen von seltenen zellen von fluidproben
CA2618068C (en) 2005-08-05 2016-02-16 Amgen Inc. Stable aqueous protein or antibody pharmaceutical formulations and their preparation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4439421A (en) * 1982-08-30 1984-03-27 Baxter Travenol Laboratories, Inc. Stabilized gamma globulin concentrate
US4508643A (en) * 1983-02-08 1985-04-02 Baxter Travenol Laboratories, Inc. Rat antibody to hCG
US4650772A (en) * 1984-08-09 1987-03-17 Abbott Laboratories Monoclonal antibody stabilization
EP0173648A3 (en) * 1984-08-30 1988-04-27 Ciba-Geigy Ag New monoclonal antibodies to glycoconjugates, processes for their production, and applications

Also Published As

Publication number Publication date
EP0280358B1 (en) 1992-12-30
GR3007486T3 (es) 1993-07-30
DE3877015D1 (de) 1993-02-11
EP0280358A1 (en) 1988-08-31
ATE83930T1 (de) 1993-01-15
DE3877015T2 (de) 1993-05-06
JP2655667B2 (ja) 1997-09-24
JPS63225320A (ja) 1988-09-20

Similar Documents

Publication Publication Date Title
ATE162079T1 (de) Verwendung von antikörper enthaltenden präparationen zur immunsuppression
DK0791571T3 (da) Benzoylderivater
DE3482142D1 (de) Kompilation von perform-anweisungen.
DE3880047D1 (de) Zusammensetzung eines zusatzes.
FI903464A0 (fi) Foerfarande foer oxiderande denaturering av proteinanalyter.
NO870770L (no) FremgangsmŸte for fremstilling av monoklonale antistoffer.
DE69202164D1 (de) Stabilisierung von Thiolenzusammensetzungen.
NO163745C (no) Stabiliseringsmetode.
ATE81976T1 (de) 2-pyrimidinyl-1-piperazin-derivate zur behandlung von alkoholismus.
DE3885913D1 (de) Aufbereitung von Alkoxysilanen.
DE69007922D1 (de) Dynamische Kompensation des Beschleunigungsprogrammes.
ES2053704T3 (es) Un metodo de estabilizacion de una composicion acuosa consistente en uno o mas anticuerpos monoclonales.
DE3874929D1 (de) N-silyl-substituierte 1-sila-2-azacyclopentane.
DE59003161D1 (de) STABILISIERUNG VON GLYKOSYLIERTEM t-PA.
NO177461C (no) Trijodbenzenforbindelser og kontrastmidler inneholdende disse
NO873903D0 (no) Fremgangsmaate for fremstilling av svoveldioksyd.
DE69004417D1 (de) Oral verabreichte porphyrine zur regelung der eisenabsorption.
DE58902675D1 (de) Verfahren zur steigerung des anteils an siliciumtetrachlorid.
DE3869828D1 (de) Stabilisierung von aminalane.
DE3481814D1 (de) Kosmetikum.
DE3588208D1 (de) Cephalosporinderivative
ES2053474T3 (es) 1,2,3-tiadazol-4-tiolatos substituidos.
NO912947D0 (no) Stabilisering av glykosylert t-pa.
IT1161000B (it) Congegno per l'imbottigliamento di polpa di pomodoro
DK0511516T3 (da) Schizosaccharomyces-specifikke polypeptider

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 280358

Country of ref document: ES