ZA849972B - New benzimidazoles,the preparation thereof and pharmaceutical compositions containing these compounds - Google Patents

New benzimidazoles,the preparation thereof and pharmaceutical compositions containing these compounds

Info

Publication number
ZA849972B
ZA849972B ZA849972A ZA849972A ZA849972B ZA 849972 B ZA849972 B ZA 849972B ZA 849972 A ZA849972 A ZA 849972A ZA 849972 A ZA849972 A ZA 849972A ZA 849972 B ZA849972 B ZA 849972B
Authority
ZA
South Africa
Prior art keywords
compounds
preparation
pharmaceutical compositions
compositions containing
new benzimidazoles
Prior art date
Application number
ZA849972A
Other languages
English (en)
Inventor
Norbert Hauel
Erich Mueller
Volkhard Austel
Joachim Heider
Manfred Reiffen
Willi Diederen
Jacobus Constantinus Anto Meel
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA849972B publication Critical patent/ZA849972B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA849972A 1983-12-23 1984-12-21 New benzimidazoles,the preparation thereof and pharmaceutical compositions containing these compounds ZA849972B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3346575A DE3346575A1 (de) 1983-12-23 1983-12-23 Neue benzimidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ZA849972B true ZA849972B (en) 1986-08-27

Family

ID=6217793

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA849972A ZA849972B (en) 1983-12-23 1984-12-21 New benzimidazoles,the preparation thereof and pharmaceutical compositions containing these compounds

Country Status (14)

Country Link
EP (1) EP0148431A1 (xx)
JP (1) JPS60156676A (xx)
KR (1) KR850004467A (xx)
AU (1) AU3704284A (xx)
DD (1) DD232697A5 (xx)
DE (1) DE3346575A1 (xx)
DK (1) DK597484A (xx)
ES (5) ES538929A0 (xx)
FI (1) FI845084L (xx)
HU (1) HU193073B (xx)
IL (1) IL73897A0 (xx)
NO (1) NO845169L (xx)
PT (1) PT79718B (xx)
ZA (1) ZA849972B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU85544A1 (fr) * 1984-09-19 1986-04-03 Cird Derives heterocycliques aromatiques,leur procede de preparation et leur application dans les domaines therapeutique et cosmetique
DE3522230A1 (de) * 1985-06-21 1987-01-02 Thomae Gmbh Dr K Neue 2-arylimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
FR2677020B1 (fr) * 1991-05-31 1993-08-27 Cird Galderma Composes derives de benzimidazole, leur procede de preparation et leur utilisation dans les domaines therapeutique et cosmetique.
US5821258A (en) * 1994-12-27 1998-10-13 Mitsui Chemicals, Inc. Phenylbenzimidazole derivatives
AP866A (en) * 1995-08-02 2000-08-17 Newcastle Univ Ventures Limited Benzimidazole compounds.
US5942532A (en) * 1997-09-05 1999-08-24 Ortho Pharmaceutical Corporation 2-substituted phenyl-benzimidazole antibacterial agents
EP1435947B1 (en) 2001-10-19 2007-08-15 Ortho-McNeil Pharmaceutical, Inc. 2-phenyl benzimidazoles and imidazo-¬4,5|-pyridines as cds1/chk2-inhibitors and adjuvants to chemotherapy or radiation therapy in the treatment of cancer
AU2003286757B2 (en) * 2002-11-01 2009-06-04 Merck Sharp & Dohme Corp. Carbonylamino-benzimidazole derivatives as androgen receptor modulators
CA2522562C (en) 2003-04-17 2013-09-03 Janssen Pharmaceutica N.V. 2-phenyl-benzimidazol and 2-phenyl-imidazo-`4,5!-pyridine derivatives as checkpoint kinase cds1 (chk2) inhibitors for the treatment of cancer
ATE507206T1 (de) 2004-06-30 2011-05-15 Janssen Pharmaceutica Nv Arylsubstituiertes benzimidazol- und imidazopyridinether als wirkstoffe gegen krebs
KR20130140125A (ko) 2010-12-24 2013-12-23 수미토모 케미칼 컴퍼니 리미티드 융합된 헤테로사이클릭 화합물 및 그의 해충 방제를 위한 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH350763A (de) * 1958-10-14 1960-12-15 Ciba Geigy Verwendung von Azolverbindungen als Schutzmittel gegen ultraviolette Strahlung
DE1447733B2 (de) * 1963-12-23 1977-04-21 Hoechst Ag, 6000 Frankfurt 2-(3,5-dihydroxyphenyl)-benzimidazolderivate
IL23847A (en) * 1964-08-07 1969-02-27 Merck & Co Inc Benzimidazoles useful as antifungals
FR1569337A (xx) * 1968-06-18 1969-05-30
DE2742093A1 (de) * 1977-09-19 1979-03-29 Cassella Ag Verfahren zur herstellung von 2-(3'- bzw. 4'-aminophenyl)-5(bzw. 6) -aminobenzimidazolen
DE2927987A1 (de) * 1979-07-11 1981-02-05 Thomae Gmbh Dr K Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel
DE3224512A1 (de) * 1982-07-01 1984-01-05 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
PT79718A (de) 1985-01-01
ES8601913A1 (es) 1985-11-16
JPS60156676A (ja) 1985-08-16
FI845084L (fi) 1985-06-24
ES8604163A1 (es) 1986-01-16
DK597484D0 (da) 1984-12-13
ES544119A0 (es) 1986-01-16
DE3346575A1 (de) 1985-07-04
DD232697A5 (de) 1986-02-05
FI845084A0 (fi) 1984-12-21
ES544118A0 (es) 1986-01-16
ES8604165A1 (es) 1986-01-16
KR850004467A (ko) 1985-07-15
ES538929A0 (es) 1985-11-16
NO845169L (no) 1985-06-24
ES544117A0 (es) 1986-01-16
AU3704284A (en) 1985-07-04
ES544116A0 (es) 1986-01-16
HU193073B (en) 1987-08-28
HUT37763A (en) 1986-02-28
PT79718B (de) 1986-12-30
DK597484A (da) 1985-06-24
EP0148431A1 (de) 1985-07-17
ES8604164A1 (es) 1986-01-16
IL73897A0 (en) 1985-03-31
ES8604162A1 (es) 1986-01-16

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