ZA846525B - (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof - Google Patents

(substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof

Info

Publication number
ZA846525B
ZA846525B ZA846525A ZA846525A ZA846525B ZA 846525 B ZA846525 B ZA 846525B ZA 846525 A ZA846525 A ZA 846525A ZA 846525 A ZA846525 A ZA 846525A ZA 846525 B ZA846525 B ZA 846525B
Authority
ZA
South Africa
Prior art keywords
aliphatic
phenyl
substituted
preparation
antiviral agents
Prior art date
Application number
ZA846525A
Other languages
English (en)
Inventor
Guy Dominic Diana
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of ZA846525B publication Critical patent/ZA846525B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA846525A 1983-08-29 1984-08-22 (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof ZA846525B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52758383A 1983-08-29 1983-08-29

Publications (1)

Publication Number Publication Date
ZA846525B true ZA846525B (en) 1985-04-24

Family

ID=24102064

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA846525A ZA846525B (en) 1983-08-29 1984-08-22 (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof

Country Status (3)

Country Link
US (1) US4857539A (es)
JP (1) JPS6089482A (es)
ZA (1) ZA846525B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002960A (en) * 1983-08-29 1991-03-26 Sterling Drug, Inc. N-haloalkyl-4-(isoxazol-5-yl)alkoxy benzamides
US5051437A (en) * 1986-06-24 1991-09-24 Sterling Drug Inc. Thiazolylphenoxyalkylisoxazoles, related compounds, and their use as antiviral agents
GB8807275D0 (en) * 1988-03-26 1988-04-27 Synphar Lab Inc Chemical compounds
US5175178A (en) * 1989-08-21 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US4942241A (en) * 1989-08-21 1990-07-17 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US4945164A (en) * 1989-08-18 1990-07-31 Sterling Drug Inc. 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof
US5110821A (en) * 1989-08-18 1992-05-05 Sterling Drug Inc. 1,3,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5420289A (en) * 1989-10-27 1995-05-30 American Home Products Corporation Substituted indole-, indene-, pyranoindole- and tetrahydrocarbazole-alkanoic acid derivatives as inhibitors of PLA2 and lipoxygenase
ZA9010357B (en) * 1989-12-26 1992-08-26 Janssen Pharmaceutica Nv Antipicornaviral pyridazinamines
IT1247509B (it) * 1991-04-19 1994-12-17 Univ Cagliari Composti di sintesi atti all'impiego nella terapia delle infezioni da rhinovirus
US5175177A (en) * 1991-07-17 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5349068A (en) * 1992-04-15 1994-09-20 Sterling Winthrop Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5637708A (en) * 1994-03-07 1997-06-10 President And Fellows Of Harvard College Structure based design of capsid stabilizing or antiviral agents
US5514679A (en) * 1994-05-13 1996-05-07 Sterling Winthrop Inc. Therapeutic phenoxyalklpyridazines and intermediates therefor
US5552420A (en) * 1994-05-13 1996-09-03 Sterling Winthrop Inc. Therapeutic phenoxyalkylazoles and phenoxyalkylazines
CA2188809A1 (en) * 1994-05-13 1995-11-23 Gee-Hong Kuo Therapeutic phenoxyalkylazoles and phenoxyalkylazines
US5527920A (en) * 1994-11-18 1996-06-18 Singh; Inder P. Economical manufacturing process for 1,2,3-triazoles
US5763461A (en) * 1995-05-26 1998-06-09 Sanofi Therapeutic phenoxyalkylheterocycles
IT1299263B1 (it) * 1998-05-15 2000-02-29 Univ Catania 5-aril-4-isossazolcarbonitrili 3 sostituiti ad attivita' antivirale
AUPQ105499A0 (en) 1999-06-18 1999-07-08 Biota Scientific Management Pty Ltd Antiviral agents
AUPR213700A0 (en) * 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents
CN103102348B (zh) * 2011-11-14 2016-06-08 上海交通大学 噁二唑类化合物及其制备方法、药物组合物及其用途
JP6427695B2 (ja) * 2015-10-26 2018-11-21 ジァンスー カニオン パーマスーティカル カンパニー リミテッド １，２，５−チアジアゾリジン−１，１−ジオキシドの塩形態、結晶形態及びその調製方法と中間体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE756663A (fr) * 1969-09-27 1971-03-25 Bayer Ag Composition destinee a la regulation de la croissance des vegetaux
DE1964995A1 (de) * 1969-12-24 1971-07-01 Bayer Ag N-Benzyltriazole,Verfahren zu ihrer Herstellung und ihre Verwendung zur Regulierung des Pflanzenwachstums
US4069332A (en) * 1976-09-10 1978-01-17 The Upjohn Company Compounds, compositions and methods of use
US4171365A (en) * 1977-08-05 1979-10-16 Sterling Drug Inc. Antiviral aryloxyalkylpyrazoles
US4268678A (en) * 1979-09-04 1981-05-19 Sterling Drug Inc. 4-(Arylaliphatic)isoxazoles
US4451476A (en) * 1982-12-13 1984-05-29 Sterling Drug Inc. Isoxazoles as antiviral agents
NZ209209A (en) * 1983-08-29 1988-02-12 Sterling Drug Inc Substituted phenyl-aliphatic isoxazole derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
US4857539A (en) 1989-08-15
JPH0572394B2 (es) 1993-10-12
JPS6089482A (ja) 1985-05-20

Similar Documents

Publication Publication Date Title
PH23593A (en) Difluoronucleosides as antiviral agents
ZA846525B (en) (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof
EP0137242A3 (en) (substituted) phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof
DE3478788D1 (en) Phenothiazone derivatives and analogs
SG4890G (en) 1-pyrimidinyloxy-3-hetarylalkylamino-2-propanols preparation and uses
GB8320308D0 (en) Antiviral combinations
DE3374569D1 (en) Siloxane-polyester compositions and use thereof
GB2140860B (en) Releasable clasp
IL71679A0 (en) Hydroxyethyl-azolyl derivatives and antiviral agents containing them
GB2135329B (en) Substituted 4-amino-3-nitrophenols processes for their preparation and hair-colouring agents containing them
ZA842202B (en) Phenylaminobenzenealkanols and preparation
GB2138293B (en) Novel pesticidal compositions and their use
ZA845263B (en) Pyridinyl-2-pyrimidinamines useful as cardiotonics and preparation thereof
GB2150570B (en) Novel antiviral agents
DE3468322D1 (en) Antiviral agent
GB2184944B (en) Antiviral agents
GB8301754D0 (en) Formulation
GB8428144D0 (en) Hydrophilic-film-forming preparation
GB2207864B (en) Antiviral composition comprising isopropyldeoxyuridine
ZA84442B (en) Phenothiazone derivatives and analogs
GB2141121B (en) 1-phenoxy-3-hydroxyindolyl-alkylamino-3-propanols and preparation
DE3472250D1 (en) Novel halonitriles and their preparation
ZA844744B (en) Antiviral agents
YU114783A (en) "hidrovtol" airplane
IL69414A0 (en) Cosmetic-pharmaceutical formulation