ZA839070B - New therapeutically useful pyrrolidine derivatives - Google Patents

New therapeutically useful pyrrolidine derivatives

Info

Publication number
ZA839070B
ZA839070B ZA839070A ZA839070A ZA839070B ZA 839070 B ZA839070 B ZA 839070B ZA 839070 A ZA839070 A ZA 839070A ZA 839070 A ZA839070 A ZA 839070A ZA 839070 B ZA839070 B ZA 839070B
Authority
ZA
South Africa
Prior art keywords
alkyl
radical
alkoxy
atom
therapeutically useful
Prior art date
Application number
ZA839070A
Other languages
English (en)
Inventor
Jean-Louis Fabre
Daniel Farge
James Claude
Daniel Lave
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of ZA839070B publication Critical patent/ZA839070B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
ZA839070A 1982-12-07 1983-12-06 New therapeutically useful pyrrolidine derivatives ZA839070B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8220492A FR2537133A1 (fr) 1982-12-07 1982-12-07 Nouveaux derives de la (piperazinyl-1)-5 pyrrolidine, leur preparation et les medicaments qui les contiennent

Publications (1)

Publication Number Publication Date
ZA839070B true ZA839070B (en) 1984-07-25

Family

ID=9279863

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA839070A ZA839070B (en) 1982-12-07 1983-12-06 New therapeutically useful pyrrolidine derivatives

Country Status (25)

Country Link
US (1) US4547504A (sv)
EP (1) EP0110795B1 (sv)
JP (1) JPS59110670A (sv)
AT (1) ATE18548T1 (sv)
AU (1) AU560075B2 (sv)
BG (1) BG40808A3 (sv)
CA (1) CA1208645A (sv)
CS (1) CS240982B2 (sv)
DD (1) DD213216A5 (sv)
DE (1) DE3362566D1 (sv)
DK (1) DK562783A (sv)
ES (1) ES527897A0 (sv)
FI (1) FI76320C (sv)
FR (1) FR2537133A1 (sv)
GR (1) GR72855B (sv)
HU (1) HU191903B (sv)
IE (1) IE56453B1 (sv)
IL (1) IL70396A (sv)
MA (1) MA19966A1 (sv)
NO (1) NO158218C (sv)
NZ (1) NZ206498A (sv)
PL (1) PL141385B1 (sv)
PT (1) PT77774B (sv)
SU (1) SU1240359A3 (sv)
ZA (1) ZA839070B (sv)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81669A (en) * 1986-02-27 1990-11-29 Duphar Int Res Aryl-substituted(n-piperidinyl)methyl-and(n-piperazinyl)-methylazoles,their preparation and pharmaceutical compositions containing them
US5066663A (en) * 1990-05-21 1991-11-19 Warner-Lambert Company Substituted-hetero-cyclopentanones and cyclopentenones and derivatives thereof acting at muscarinic receptors
US6897213B1 (en) 1995-11-21 2005-05-24 Warner-Lambert Company Heterocycles as cholecystokinin (CCK) ligands
US5969138A (en) * 1996-11-01 1999-10-19 Mitsui Chemicals, Inc. Pyrrolidinone derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4247549A (en) * 1978-12-27 1981-01-27 Ici Americas Inc. Piperazine-1-carboxylic acid esters possessing antidepressant or analgesic activity

Also Published As

Publication number Publication date
IE56453B1 (en) 1991-08-14
CA1208645A (fr) 1986-07-29
AU2210883A (en) 1984-06-14
US4547504A (en) 1985-10-15
ES8406436A1 (es) 1984-08-01
DK562783D0 (da) 1983-12-06
IL70396A (en) 1986-11-30
CS240982B2 (en) 1986-03-13
AU560075B2 (en) 1987-03-26
FI76320C (sv) 1988-10-10
EP0110795A1 (fr) 1984-06-13
NO158218B (no) 1988-04-25
HU191903B (en) 1987-04-28
PT77774B (fr) 1986-07-11
DE3362566D1 (en) 1986-04-17
MA19966A1 (fr) 1984-07-01
FR2537133B1 (sv) 1985-05-17
FR2537133A1 (fr) 1984-06-08
CS904183A2 (en) 1985-06-13
PL141385B1 (en) 1987-07-31
IL70396A0 (en) 1984-03-30
FI834453A0 (fi) 1983-12-05
ES527897A0 (es) 1984-08-01
GR72855B (sv) 1983-12-08
PT77774A (fr) 1984-01-01
JPS59110670A (ja) 1984-06-26
EP0110795B1 (fr) 1986-03-12
NO834481L (no) 1984-06-08
PL244921A1 (en) 1985-03-26
DD213216A5 (de) 1984-09-05
BG40808A3 (en) 1987-02-16
FI76320B (fi) 1988-06-30
FI834453A (fi) 1984-06-08
SU1240359A3 (ru) 1986-06-23
NO158218C (no) 1988-08-03
ATE18548T1 (de) 1986-03-15
NZ206498A (en) 1986-05-09
DK562783A (da) 1984-06-08
IE832867L (en) 1984-06-07

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