FI834453A - Nya pyrrolidin-derivat, deras frarmstaellning och dessa innehaollande laekemedel. - Google Patents

Nya pyrrolidin-derivat, deras frarmstaellning och dessa innehaollande laekemedel. Download PDF

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Publication number
FI834453A
FI834453A FI834453A FI834453A FI834453A FI 834453 A FI834453 A FI 834453A FI 834453 A FI834453 A FI 834453A FI 834453 A FI834453 A FI 834453A FI 834453 A FI834453 A FI 834453A
Authority
FI
Finland
Prior art keywords
alkyl
radical
alkoxy
pyrrolidine derivatives
frarmstaellning
Prior art date
Application number
FI834453A
Other languages
English (en)
Other versions
FI834453A0 (fi
FI76320B (fi
FI76320C (fi
Inventor
Jean-Louis Fabre
Daniel Farge
Claude James
Daniel Lave
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of FI834453A0 publication Critical patent/FI834453A0/fi
Publication of FI834453A publication Critical patent/FI834453A/fi
Publication of FI76320B publication Critical patent/FI76320B/fi
Application granted granted Critical
Publication of FI76320C publication Critical patent/FI76320C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Steroid Compounds (AREA)
FI834453A 1982-12-07 1983-12-05 Foerfarande foer framstaellning av nya 4-fenylalkyl-5-piperazin-1-ylpyrrolidinderivat, vilka har antidepressiv verkan. FI76320C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8220492A FR2537133A1 (fr) 1982-12-07 1982-12-07 Nouveaux derives de la (piperazinyl-1)-5 pyrrolidine, leur preparation et les medicaments qui les contiennent
FR8220492 1982-12-07

Publications (4)

Publication Number Publication Date
FI834453A0 FI834453A0 (fi) 1983-12-05
FI834453A true FI834453A (fi) 1984-06-08
FI76320B FI76320B (fi) 1988-06-30
FI76320C FI76320C (fi) 1988-10-10

Family

ID=9279863

Family Applications (1)

Application Number Title Priority Date Filing Date
FI834453A FI76320C (fi) 1982-12-07 1983-12-05 Foerfarande foer framstaellning av nya 4-fenylalkyl-5-piperazin-1-ylpyrrolidinderivat, vilka har antidepressiv verkan.

Country Status (25)

Country Link
US (1) US4547504A (fi)
EP (1) EP0110795B1 (fi)
JP (1) JPS59110670A (fi)
AT (1) ATE18548T1 (fi)
AU (1) AU560075B2 (fi)
BG (1) BG40808A3 (fi)
CA (1) CA1208645A (fi)
CS (1) CS240982B2 (fi)
DD (1) DD213216A5 (fi)
DE (1) DE3362566D1 (fi)
DK (1) DK562783A (fi)
ES (1) ES527897A0 (fi)
FI (1) FI76320C (fi)
FR (1) FR2537133A1 (fi)
GR (1) GR72855B (fi)
HU (1) HU191903B (fi)
IE (1) IE56453B1 (fi)
IL (1) IL70396A (fi)
MA (1) MA19966A1 (fi)
NO (1) NO158218C (fi)
NZ (1) NZ206498A (fi)
PL (1) PL141385B1 (fi)
PT (1) PT77774B (fi)
SU (1) SU1240359A3 (fi)
ZA (1) ZA839070B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1279645C (en) * 1986-02-27 1991-01-29 Ineke Van Wijngaarden Aryl-substituted (n-piperidinyl)methyl- and (n-piperazinyl)methylazoles having antipsychotic properties
US5066663A (en) * 1990-05-21 1991-11-19 Warner-Lambert Company Substituted-hetero-cyclopentanones and cyclopentenones and derivatives thereof acting at muscarinic receptors
US6897213B1 (en) 1995-11-21 2005-05-24 Warner-Lambert Company Heterocycles as cholecystokinin (CCK) ligands
US5969138A (en) * 1996-11-01 1999-10-19 Mitsui Chemicals, Inc. Pyrrolidinone derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4247549A (en) * 1978-12-27 1981-01-27 Ici Americas Inc. Piperazine-1-carboxylic acid esters possessing antidepressant or analgesic activity

Also Published As

Publication number Publication date
ES8406436A1 (es) 1984-08-01
IE832867L (en) 1984-06-07
NO158218C (no) 1988-08-03
FI834453A0 (fi) 1983-12-05
DE3362566D1 (en) 1986-04-17
US4547504A (en) 1985-10-15
NO158218B (no) 1988-04-25
CS904183A2 (en) 1985-06-13
AU2210883A (en) 1984-06-14
FI76320B (fi) 1988-06-30
IL70396A (en) 1986-11-30
FR2537133B1 (fi) 1985-05-17
MA19966A1 (fr) 1984-07-01
AU560075B2 (en) 1987-03-26
CS240982B2 (en) 1986-03-13
DK562783A (da) 1984-06-08
GR72855B (fi) 1983-12-08
FR2537133A1 (fr) 1984-06-08
ATE18548T1 (de) 1986-03-15
BG40808A3 (en) 1987-02-16
DD213216A5 (de) 1984-09-05
PT77774B (fr) 1986-07-11
IE56453B1 (en) 1991-08-14
ZA839070B (en) 1984-07-25
PL141385B1 (en) 1987-07-31
EP0110795A1 (fr) 1984-06-13
FI76320C (fi) 1988-10-10
NO834481L (no) 1984-06-08
CA1208645A (fr) 1986-07-29
NZ206498A (en) 1986-05-09
HU191903B (en) 1987-04-28
DK562783D0 (da) 1983-12-06
EP0110795B1 (fr) 1986-03-12
SU1240359A3 (ru) 1986-06-23
JPS59110670A (ja) 1984-06-26
IL70396A0 (en) 1984-03-30
PT77774A (fr) 1984-01-01
PL244921A1 (en) 1985-03-26
ES527897A0 (es) 1984-08-01

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: RHONE-POULENC SANTE