ZA837827B - Substituted 9h-8-oxy-pyrimido(2,1-f)purine-2,4-diones,process for their production and pharmaceutical compositions containing them - Google Patents

Substituted 9h-8-oxy-pyrimido(2,1-f)purine-2,4-diones,process for their production and pharmaceutical compositions containing them

Info

Publication number
ZA837827B
ZA837827B ZA837827A ZA837827A ZA837827B ZA 837827 B ZA837827 B ZA 837827B ZA 837827 A ZA837827 A ZA 837827A ZA 837827 A ZA837827 A ZA 837827A ZA 837827 B ZA837827 B ZA 837827B
Authority
ZA
South Africa
Prior art keywords
alkyl
aryl
cycloalkyl
hydrogen
substituted
Prior art date
Application number
ZA837827A
Other languages
English (en)
Inventor
David John Blythin
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA837827B publication Critical patent/ZA837827B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA837827A 1982-10-25 1983-10-20 Substituted 9h-8-oxy-pyrimido(2,1-f)purine-2,4-diones,process for their production and pharmaceutical compositions containing them ZA837827B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43624782A 1982-10-25 1982-10-25

Publications (1)

Publication Number Publication Date
ZA837827B true ZA837827B (en) 1984-06-27

Family

ID=23731696

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA837827A ZA837827B (en) 1982-10-25 1983-10-20 Substituted 9h-8-oxy-pyrimido(2,1-f)purine-2,4-diones,process for their production and pharmaceutical compositions containing them

Country Status (12)

Country Link
EP (1) EP0107165B1 (xx)
JP (1) JPS5993082A (xx)
AT (1) ATE26575T1 (xx)
AU (1) AU569714B2 (xx)
CA (1) CA1225645A (xx)
DE (1) DE3370961D1 (xx)
GR (1) GR79651B (xx)
HU (1) HU191884B (xx)
IL (1) IL70029A (xx)
NZ (1) NZ206021A (xx)
PT (1) PT77541B (xx)
ZA (1) ZA837827B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666914A (en) * 1985-05-13 1987-05-19 Schering Corporation Anti-inflammatory and anti-allergic substituted-2,3-dihydro-6-(hydroxy)pyrimido[2,1-f]-purine-4,8(1H,9H)-diones
US4912104A (en) * 1987-08-31 1990-03-27 Takeda Chemical Industries, Ltd. Tricyclic fused pryimidine derivatives, and their use as pharmaceuticals

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3637684A (en) * 1968-01-05 1972-01-25 Pfizer Preparation of heterocycloimidazoles
AT361503B (de) * 1978-10-04 1981-03-10 Chinoin Gyogyszer Es Vegyeszet Verfahren zur herstellung neuer tetrahydro- pyrimido(2,1-f)theophylline

Also Published As

Publication number Publication date
IL70029A (en) 1987-08-31
AU2042783A (en) 1984-05-03
PT77541B (en) 1986-05-27
GR79651B (xx) 1984-10-31
CA1225645A (en) 1987-08-18
PT77541A (en) 1983-11-01
EP0107165A1 (en) 1984-05-02
NZ206021A (en) 1986-12-05
EP0107165B1 (en) 1987-04-15
ATE26575T1 (de) 1987-05-15
JPH0412274B2 (xx) 1992-03-04
AU569714B2 (en) 1988-02-18
JPS5993082A (ja) 1984-05-29
IL70029A0 (en) 1984-01-31
HU191884B (en) 1987-04-28
DE3370961D1 (en) 1987-05-21

Similar Documents

Publication Publication Date Title
DE3881246D1 (de) Durch benzhydryl n-substituierte heterocyclische derivate, ihre herstellung und ihre verwendung.
ZA896067B (en) Chemical compounds
HUT59394A (en) Process for producing piperazine derivatives and pharmaceutical compositions comprising same
HUT46895A (en) Process for production of new 5-lipoxigenase bicyclic compounds with inhibiation effect
ATE107308T1 (de) Mevalonolactone vom thienopyridin-typ.
PL249964A1 (en) Process for preparing novel derivatives of 7-//z/-2-/2-aminothiazolyl-4/-2-oxyiminoacetamide/-3-cephemo-4-carboxylic acid
IL73320A0 (en) Purine derivatives and pharmaceutical compositions containing them
DE3370961D1 (en) Substituted 9h-8-oxo-pyrimido(2,1-f)purine-2,4-diones, process for their production and pharmaceutical compositions containing them
ES2010145A6 (es) Procedimiento para la obtencion de derivados de la 2-picolilamina.
PT73841B (en) Process for preparing novel guanidine derivatives
HUT75647A (en) Imidazolidinone derivatives and pharmaceutical compositions containing them, which are suitable for treament of senile dementia
EP0486022A3 (en) Naphthalene derivatives
HUT34959A (en) Process for production of new amidine derivatives of 2-substituated-4-phenile imdadasoles
ES8304551A1 (es) Un procedimiento para preparar derivados de dialcohilpirazol
FI822697L (fi) Foerfarande och mellanprodukter foer framstaellning av benzotiazinkarboxamider
DE69401163D1 (de) Umwandlungsverfahren von Lorabef Dihydrate in Loracarbef Monohydrate
PT92175A (pt) Processo para a preparacao de 3-amino-sidnoniminas substituidas e de produtos intermediarios farmacologicamente activos
DE3366679D1 (en) Substituted heterocyclylphenylsulphonyl and phosphonyl amidines, process for their preparation and their pharmaceutical use
NZ222427A (en) 4-hydroxy-4-(substituted alkenyl)-cyclohexanecarboxylic acid derivatives and preparatory processes