ZA836358B - Intermediates useful in the preparation of 17,17-bis(substtituted thio)androstenes - Google Patents
Intermediates useful in the preparation of 17,17-bis(substtituted thio)androstenesInfo
- Publication number
- ZA836358B ZA836358B ZA836358A ZA836358A ZA836358B ZA 836358 B ZA836358 B ZA 836358B ZA 836358 A ZA836358 A ZA 836358A ZA 836358 A ZA836358 A ZA 836358A ZA 836358 B ZA836358 B ZA 836358B
- Authority
- ZA
- South Africa
- Prior art keywords
- androstenes
- hydrogen
- preparation
- substtituted
- thio
- Prior art date
Links
- 150000001443 androstenes Chemical class 0.000 title abstract 3
- 239000000543 intermediate Substances 0.000 title abstract 2
- 125000000446 sulfanediyl group Chemical group *S* 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000001589 carboacyl group Chemical group 0.000 abstract 3
- 229910052736 halogen Chemical group 0.000 abstract 3
- 150000002367 halogens Chemical group 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- -1 aroyloxyalkyl Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000005041 acyloxyalkyl group Chemical group 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005078 alkoxycarbonylalkyl group Chemical group 0.000 abstract 1
- 125000006350 alkyl thio alkyl group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000003435 aroyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000005110 aryl thio group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/416,181 US4435326A (en) | 1982-09-09 | 1982-09-09 | Intermediates useful in the preparation of 17,17-bis(substituted thio)androstenes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA836358B true ZA836358B (en) | 1984-04-25 |
Family
ID=23648912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA836358A ZA836358B (en) | 1982-09-09 | 1983-08-26 | Intermediates useful in the preparation of 17,17-bis(substtituted thio)androstenes |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4435326A (https=) |
| EP (1) | EP0105224B1 (https=) |
| JP (1) | JPS5967299A (https=) |
| AT (1) | ATE25089T1 (https=) |
| AU (1) | AU558201B2 (https=) |
| CA (1) | CA1248087A (https=) |
| DE (1) | DE3369326D1 (https=) |
| DK (1) | DK164873C (https=) |
| HU (2) | HU189744B (https=) |
| IE (1) | IE55719B1 (https=) |
| NO (1) | NO159602C (https=) |
| ZA (1) | ZA836358B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4529548A (en) * | 1984-05-07 | 1985-07-16 | E. R. Squibb & Sons, Inc. | 17β-(substituted thio)androstenes |
| US4529547A (en) * | 1984-06-20 | 1985-07-16 | E.R. Squibb & Sons, Inc. | 17-(substituted thio)-17-(substituted dithio)androstenes |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2949477A (en) * | 1959-03-04 | 1960-08-16 | Searle & Co | 1, 3, 17-triacetoxyestra-1, 3, 5(10), 16-tetraene and congeners |
| US4094840A (en) * | 1977-05-12 | 1978-06-13 | E. R. Squibb & Sons, Inc. | 17-Alkylthio (and arylthio) androsteno[16α,17α-b]benzodioxin-3-ones |
| US4091036A (en) * | 1977-05-12 | 1978-05-23 | E. R. Squibb & Sons, Inc. | 17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives |
| US4133811A (en) * | 1978-02-17 | 1979-01-09 | E. R. Squibb & Sons, Inc. | 13-Alkylthio (and arylthio)-11,17-epoxy-17-methyl-18-norandrostenes |
| US4146538A (en) * | 1978-02-27 | 1979-03-27 | E. R. Squibb & Sons, Inc. | 17-Alkylthio (and arylthio) androsteno[17α,16α-b]benzopyran-3-ones and [16α,17α]naphthopyran-3-ones |
| US4361559A (en) * | 1981-08-20 | 1982-11-30 | E. R. Squibb & Sons, Inc. | Antiinflammatory 17,17-bis (substituted thio) androstenes |
-
1982
- 1982-09-09 US US06/416,181 patent/US4435326A/en not_active Expired - Fee Related
-
1983
- 1983-08-24 CA CA000435269A patent/CA1248087A/en not_active Expired
- 1983-08-25 AU AU18433/83A patent/AU558201B2/en not_active Ceased
- 1983-08-26 ZA ZA836358A patent/ZA836358B/xx unknown
- 1983-09-05 IE IE2080/83A patent/IE55719B1/en not_active IP Right Cessation
- 1983-09-08 DE DE8383108886T patent/DE3369326D1/de not_active Expired
- 1983-09-08 HU HU833143A patent/HU189744B/hu not_active IP Right Cessation
- 1983-09-08 AT AT83108886T patent/ATE25089T1/de not_active IP Right Cessation
- 1983-09-08 HU HU834616A patent/HU196432B/hu not_active IP Right Cessation
- 1983-09-08 DK DK407983A patent/DK164873C/da not_active IP Right Cessation
- 1983-09-08 JP JP58166447A patent/JPS5967299A/ja active Granted
- 1983-09-08 EP EP83108886A patent/EP0105224B1/en not_active Expired
- 1983-09-08 NO NO833208A patent/NO159602C/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0105224A3 (en) | 1984-08-01 |
| JPS5967299A (ja) | 1984-04-16 |
| DE3369326D1 (en) | 1987-02-26 |
| IE55719B1 (en) | 1991-01-02 |
| AU558201B2 (en) | 1987-01-22 |
| NO159602C (no) | 1989-01-18 |
| HU189744B (en) | 1986-07-28 |
| DK407983A (da) | 1984-03-10 |
| JPH0439478B2 (https=) | 1992-06-29 |
| ATE25089T1 (de) | 1987-02-15 |
| US4435326A (en) | 1984-03-06 |
| NO833208L (no) | 1984-03-12 |
| NO159602B (no) | 1988-10-10 |
| IE832080L (en) | 1984-03-09 |
| HU196432B (en) | 1988-11-28 |
| DK407983D0 (da) | 1983-09-08 |
| EP0105224A2 (en) | 1984-04-11 |
| EP0105224B1 (en) | 1987-01-21 |
| DK164873C (da) | 1993-01-11 |
| CA1248087A (en) | 1989-01-03 |
| AU1843383A (en) | 1984-03-15 |
| DK164873B (da) | 1992-08-31 |
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