ZA836330B - 1,2,3,4-tetrahydro-1-aminomethyl-4-phenyl isoquinolines and methods of preparation - Google Patents

1,2,3,4-tetrahydro-1-aminomethyl-4-phenyl isoquinolines and methods of preparation

Info

Publication number
ZA836330B
ZA836330B ZA836330A ZA836330A ZA836330B ZA 836330 B ZA836330 B ZA 836330B ZA 836330 A ZA836330 A ZA 836330A ZA 836330 A ZA836330 A ZA 836330A ZA 836330 B ZA836330 B ZA 836330B
Authority
ZA
South Africa
Prior art keywords
aminomethyl
tetrahydro
preparation
methods
phenyl
Prior art date
Application number
ZA836330A
Other languages
English (en)
Inventor
Ronald C Griffith
Original Assignee
Pennwalt Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pennwalt Corp filed Critical Pennwalt Corp
Publication of ZA836330B publication Critical patent/ZA836330B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA836330A 1982-09-27 1983-08-26 1,2,3,4-tetrahydro-1-aminomethyl-4-phenyl isoquinolines and methods of preparation ZA836330B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/423,958 US4518779A (en) 1982-09-27 1982-09-27 1,2,3,4-Tetrahydro-1-aminomethyl-4-phenyl isoquinolines

Publications (1)

Publication Number Publication Date
ZA836330B true ZA836330B (en) 1984-07-25

Family

ID=23680888

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA836330A ZA836330B (en) 1982-09-27 1983-08-26 1,2,3,4-tetrahydro-1-aminomethyl-4-phenyl isoquinolines and methods of preparation

Country Status (17)

Country Link
US (1) US4518779A (da)
EP (1) EP0104604B1 (da)
JP (1) JPS5978164A (da)
KR (1) KR840006209A (da)
AT (1) ATE34386T1 (da)
AU (1) AU564040B2 (da)
BR (1) BR8305272A (da)
CA (1) CA1228360A (da)
DE (1) DE3376650D1 (da)
DK (1) DK438883A (da)
FI (1) FI833443L (da)
IE (1) IE55970B1 (da)
IL (1) IL69624A (da)
NO (1) NO833465L (da)
NZ (1) NZ205422A (da)
PH (1) PH19712A (da)
ZA (1) ZA836330B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0330360B1 (en) * 1988-02-19 1993-12-01 SmithKline Beecham Farmaceutici S.p.A. 1,2,3,4-Tetrahydroisoquinolines, processes for their preparation, and their use as kappa-receptor agonists
GB8827479D0 (en) * 1988-11-24 1988-12-29 Zambeletti Spa L Novel compounds
CA3032302A1 (en) * 2016-07-29 2018-02-01 Taleen G. Hanania Compounds and compositions and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3420818A (en) * 1964-08-07 1969-01-07 Sandoz Ag Tetrahydroisoquinolines
US3435038A (en) * 1965-06-01 1969-03-25 Sandoz Ag 5,6,7,9,10,14b-hexahydroisoquinolo (2,1-d) benzo (1,4) diazepines
US3666763A (en) * 1970-01-06 1972-05-30 Hoffmann La Roche 4-phenyl isoquinolines and process for preparing same
US4220647A (en) * 1974-11-06 1980-09-02 Fujisawa Pharmaceutical Co., Ltd. 1,2,3,4-Tetrahydroisoquinolines and the preparation thereof
DE2811361A1 (de) * 1978-03-16 1979-09-27 Hoechst Ag Neue isochinolinaldehyde und verfahren zu ihrer herstellung
JPS5587771A (en) * 1978-12-27 1980-07-02 Teikoku Hormone Mfg Co Ltd 1-phenylisoquinoline derivative
DE3011156A1 (de) * 1980-03-22 1981-10-01 Merck Patent Gmbh, 6100 Darmstadt Verfahren zur herstellung von isochinolinderivaten
US4340600A (en) * 1980-05-22 1982-07-20 Smithkline Corporation Renal dilating methods and compositions using 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines

Also Published As

Publication number Publication date
AU564040B2 (en) 1987-07-30
IE55970B1 (en) 1991-03-13
FI833443A0 (fi) 1983-09-26
IL69624A0 (en) 1983-12-30
JPS5978164A (ja) 1984-05-04
DK438883A (da) 1984-03-28
EP0104604B1 (en) 1988-05-18
NZ205422A (en) 1986-07-11
KR840006209A (ko) 1984-11-22
BR8305272A (pt) 1984-05-02
CA1228360A (en) 1987-10-20
IL69624A (en) 1987-01-30
PH19712A (en) 1986-06-17
DE3376650D1 (en) 1988-06-23
IE832205L (en) 1984-03-27
AU1911283A (en) 1984-04-05
EP0104604A1 (en) 1984-04-04
FI833443A7 (fi) 1984-03-28
ATE34386T1 (de) 1988-06-15
FI833443L (fi) 1984-03-28
DK438883D0 (da) 1983-09-26
NO833465L (no) 1984-03-28
US4518779A (en) 1985-05-21

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