ZA835673B - Fused 4h-1,4-benzothiazines,processes for their preparation,and their use as medicaments - Google Patents

Fused 4h-1,4-benzothiazines,processes for their preparation,and their use as medicaments

Info

Publication number
ZA835673B
ZA835673B ZA835673A ZA835673A ZA835673B ZA 835673 B ZA835673 B ZA 835673B ZA 835673 A ZA835673 A ZA 835673A ZA 835673 A ZA835673 A ZA 835673A ZA 835673 B ZA835673 B ZA 835673B
Authority
ZA
South Africa
Prior art keywords
benzothiazines
medicaments
fused
processes
preparation
Prior art date
Application number
ZA835673A
Other languages
English (en)
Inventor
Ekkehard Niemers
Rudi Gruetzmann
Mardin Mithat
Wolf-Dieter Busse
Horst Meyer
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA835673B publication Critical patent/ZA835673B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/20—[b, e]-condensed with two six-membered rings with hydrogen atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA835673A 1982-08-04 1983-08-03 Fused 4h-1,4-benzothiazines,processes for their preparation,and their use as medicaments ZA835673B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823229122 DE3229122A1 (de) 1982-08-04 1982-08-04 Anellierte 4h-1,4-benzothiazine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ZA835673B true ZA835673B (en) 1984-04-25

Family

ID=6170117

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA835673A ZA835673B (en) 1982-08-04 1983-08-03 Fused 4h-1,4-benzothiazines,processes for their preparation,and their use as medicaments

Country Status (16)

Country Link
US (1) US4636497A (cs)
EP (1) EP0101898A1 (cs)
JP (1) JPS5944370A (cs)
KR (1) KR840005725A (cs)
AU (1) AU1741483A (cs)
DE (1) DE3229122A1 (cs)
DK (1) DK354583A (cs)
ES (1) ES524713A0 (cs)
FI (1) FI832784A7 (cs)
GR (1) GR79355B (cs)
HU (1) HU189314B (cs)
IL (1) IL69388A0 (cs)
NO (1) NO832625L (cs)
PH (1) PH18784A (cs)
PT (1) PT77097B (cs)
ZA (1) ZA835673B (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0138481B1 (en) * 1983-10-05 1991-06-26 Merck Frosst Canada Inc. Leukotriene biosynthesis inhibitors
EP0149297B1 (en) * 1983-12-27 1987-11-25 Merck Frosst Canada Inc. Process for preparing 3h-phenothlazin-3-ones
EP0155623A3 (en) * 1984-03-19 1985-12-27 Merck & Co. Inc. Use of lipoxygenase inhibitors for the preparations of cytoprotective pharmaceutical compostions and process for the preparation of a cytoprotective pharmaceutical composition
US4500708A (en) * 1984-04-23 1985-02-19 G. D. Serle & Co. Benzothiazine derivatives
DE3426564A1 (de) * 1984-07-19 1986-01-30 Bayer Ag, 5090 Leverkusen Verwendung von 4h-1,4-benzothiazinen bei der prophylaxe und therapie von erkrankungen der atemwege, entzuendungen/rheuma, thromboembolischen erkrankungen, ischaemien und infarkten, herzrhythmusstoerungen, arteriosklerose und dermatosen, arzneimittel zu diesem zweck sowie wirkstoffe, die in diesen arzneimitteln enthalten sind
DE3540702A1 (de) * 1985-11-16 1987-05-21 Bayer Ag 1h-pyrido-(2,3-b) (1,4)-thiazine
DE3545097A1 (de) * 1985-12-19 1987-07-02 Bayer Ag 1-h-pyrido-(3,2-b)(1,4)-thiazine
US4921838A (en) * 1987-06-16 1990-05-01 Trustees Of Boston University Angiogenic and blood perfusion inducing properties of amphiphilic compounds
US5981294A (en) * 1995-11-29 1999-11-09 Metrika, Inc. Device for blood separation in a diagnostic device
US5994349A (en) * 1997-10-27 1999-11-30 Howard University 3-carboalkoxy-2, 3-dihydro-1H-phenothiazin-4[10H]-one derivatives
RU2167156C1 (ru) * 2000-02-11 2001-05-20 Государственный научный центр РФ "НИОПИК" Способ получения 2-трифторметилфенотиазина

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1088055B (de) * 1958-05-16 1960-09-01 Chem Fab Promonta Ges Mit Besc Verfahren zur Herstellung von Hexahydrophenthiazin-9-dioxyden
DE1151802B (de) * 1960-04-28 1963-07-25 Chem Fab Promonta Ges Mit Besc Verfahren zur Herstellung von cycloalkylierten 2,3-Dihydro-1,4-benzthiazinen
US3422101A (en) * 1967-05-05 1969-01-14 Mcneilab Inc Tetrahydrothienobenzothiazines
US4512990A (en) * 1982-02-18 1985-04-23 Syntex (U.S.A.), Inc. Benzthiazine analogs as antiinflammatory agents

Also Published As

Publication number Publication date
HU189314B (en) 1986-06-30
FI832784L (fi) 1984-02-05
GR79355B (cs) 1984-10-22
FI832784A7 (fi) 1984-02-05
IL69388A0 (en) 1983-11-30
PT77097A (en) 1983-08-01
ES8404607A1 (es) 1984-05-01
EP0101898A1 (de) 1984-03-07
NO832625L (no) 1984-02-06
JPS5944370A (ja) 1984-03-12
KR840005725A (ko) 1984-11-16
DK354583A (da) 1984-02-05
AU1741483A (en) 1984-02-09
FI832784A0 (fi) 1983-08-02
DK354583D0 (da) 1983-08-03
ES524713A0 (es) 1984-05-01
DE3229122A1 (de) 1984-02-09
PT77097B (en) 1986-03-12
PH18784A (en) 1985-09-25
US4636497A (en) 1987-01-13

Similar Documents

Publication Publication Date Title
ZA83743B (en) Pyrazolooxazines,pyrazolothiazines,and pyrazoloquinolines,process for their preparation and their use as medicaments
DE3366841D1 (en) Fibrinogen preparation, process for its manufacture and use thereof
DE3368610D1 (en) Phenyl-1-piperidino-2-propanol derivatives, their preparation and medicaments containing them
IL68620A0 (en) Bicyclic compounds,their manufacture and pharmaceutical compositions containing them
ZA841393B (en) Fused imidazole compounds,processes for preparation thereof and pharmaceutical composition comprising the same
KE3545A (en) 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridine-3-carboxylic acids,processes for their preparation and medicaments containing these compounds
DE3377795D1 (en) Spergualin-related compounds, processes for the preparation thereof and their use as medicaments
ZM9283A1 (en) Substituted phenylsulfonyloxybenzimidazolecarbamates,processes for their preparation and pharmaceutical compositions containing the same
YU110483A (en) Process for obtaining new oxazionobenzothiazine-6,6-dioxide derivatives and use thereof as medicaments
ZA836072B (en) Desoxyuridine derivatives,processes for their preparation and their use as pharmaceuticals
ZA835673B (en) Fused 4h-1,4-benzothiazines,processes for their preparation,and their use as medicaments
DE3161358D1 (en) Tricyclic ethers, processes for their preparation and their use as medicaments
ZA813002B (en) Substituted trcyclic thieno compounds,processes for their preparation,their use and medicaments containing them
ZA854287B (en) Dialkoxypyridines,process for their preparation,their use and medicaments containing them
AR242389A1 (es) Procedimiento para preparar -di-(n-alquil c1-c4)-amino-4,5-dihidroimidazo¡1,2-a¿quinazolin-2(1h)-onas.
DE3368061D1 (en) Azabicycloalkane derivatives, their preparation and medicaments containing them
IL70488A0 (en) Fluoromethylthiooxacephalosporins,processes for the preparation thereof and pharmaceutical and veterinary compositions containing the same
ZA83592B (en) Corynantheine derivatives,processes for their preparation,and their use
DE3364376D1 (en) Isoindolazines, process for their preparation and their use
GR80474B (en) Chinazolinderivatives, method for the preparation thereof, and medicaments containing said compounds
IL63025A (en) Carbamoyloxyamino-1,4-benzodiazepines,process for their preparation and medicaments containing these compounds
DE3166751D1 (en) Pentapeptides of the encephaline type, process for their preparation and medicaments containing these
DE3369132D1 (en) Process for the preparation of isomelamines, and their use
ZA832069B (en) 7-a-aminoacyl-3-chlorocephalosporins,process for their preparation and their use as medicaments
DE3372968D1 (en) Heterocyclyl-thio compounds, process for their preparation, pharmaceutical compositions containing them and their use