PT77097B - Process for the preparation of 4h-1,4-curied benzothiazines having a lipoxygenase inhibition effect and their application for the preparation of pharmaceutical compositions having a lipoxygenase inhibition effect - Google Patents
Process for the preparation of 4h-1,4-curied benzothiazines having a lipoxygenase inhibition effect and their application for the preparation of pharmaceutical compositions having a lipoxygenase inhibition effectInfo
- Publication number
- PT77097B PT77097B PT77097A PT7709783A PT77097B PT 77097 B PT77097 B PT 77097B PT 77097 A PT77097 A PT 77097A PT 7709783 A PT7709783 A PT 7709783A PT 77097 B PT77097 B PT 77097B
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- inhibition effect
- lipoxygenase inhibition
- curied
- benzothiazines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/20—[b, e]-condensed with two six-membered rings with hydrogen atoms directly attached to the ring nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823229122 DE3229122A1 (de) | 1982-08-04 | 1982-08-04 | Anellierte 4h-1,4-benzothiazine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT77097A PT77097A (en) | 1983-08-01 |
| PT77097B true PT77097B (en) | 1986-03-12 |
Family
ID=6170117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT77097A PT77097B (en) | 1982-08-04 | 1983-07-25 | Process for the preparation of 4h-1,4-curied benzothiazines having a lipoxygenase inhibition effect and their application for the preparation of pharmaceutical compositions having a lipoxygenase inhibition effect |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4636497A (pt) |
| EP (1) | EP0101898A1 (pt) |
| JP (1) | JPS5944370A (pt) |
| KR (1) | KR840005725A (pt) |
| AU (1) | AU1741483A (pt) |
| DE (1) | DE3229122A1 (pt) |
| DK (1) | DK354583A (pt) |
| ES (1) | ES8404607A1 (pt) |
| FI (1) | FI832784A (pt) |
| GR (1) | GR79355B (pt) |
| HU (1) | HU189314B (pt) |
| IL (1) | IL69388A0 (pt) |
| NO (1) | NO832625L (pt) |
| PH (1) | PH18784A (pt) |
| PT (1) | PT77097B (pt) |
| ZA (1) | ZA835673B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3484745D1 (de) * | 1983-10-05 | 1991-08-01 | Merck Frosst Canada Inc | Inhibitoren fuer die leukotrien-biosynthese. |
| JPS60139680A (ja) * | 1983-12-27 | 1985-07-24 | メルク フロスト カナダ，インコ−ポレ−テツド | ３ｈ−フエノチアジン−３−オン類の製法 |
| EP0155623A3 (en) * | 1984-03-19 | 1985-12-27 | Merck & Co. Inc. | Use of lipoxygenase inhibitors for the preparations of cytoprotective pharmaceutical compostions and process for the preparation of a cytoprotective pharmaceutical composition |
| US4500708A (en) * | 1984-04-23 | 1985-02-19 | G. D. Serle & Co. | Benzothiazine derivatives |
| DE3426564A1 (de) * | 1984-07-19 | 1986-01-30 | Bayer Ag, 5090 Leverkusen | Verwendung von 4h-1,4-benzothiazinen bei der prophylaxe und therapie von erkrankungen der atemwege, entzuendungen/rheuma, thromboembolischen erkrankungen, ischaemien und infarkten, herzrhythmusstoerungen, arteriosklerose und dermatosen, arzneimittel zu diesem zweck sowie wirkstoffe, die in diesen arzneimitteln enthalten sind |
| DE3540702A1 (de) * | 1985-11-16 | 1987-05-21 | Bayer Ag | 1h-pyrido-(2,3-b) (1,4)-thiazine |
| DE3545097A1 (de) * | 1985-12-19 | 1987-07-02 | Bayer Ag | 1-h-pyrido-(3,2-b)(1,4)-thiazine |
| US4921838A (en) * | 1987-06-16 | 1990-05-01 | Trustees Of Boston University | Angiogenic and blood perfusion inducing properties of amphiphilic compounds |
| US5981294A (en) * | 1995-11-29 | 1999-11-09 | Metrika, Inc. | Device for blood separation in a diagnostic device |
| US5994349A (en) * | 1997-10-27 | 1999-11-30 | Howard University | 3-carboalkoxy-2, 3-dihydro-1H-phenothiazin-4[10H]-one derivatives |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1088055B (de) * | 1958-05-16 | 1960-09-01 | Chem Fab Promonta Ges Mit Besc | Verfahren zur Herstellung von Hexahydrophenthiazin-9-dioxyden |
| DE1151802B (de) * | 1960-04-28 | 1963-07-25 | Chem Fab Promonta Ges Mit Besc | Verfahren zur Herstellung von cycloalkylierten 2,3-Dihydro-1,4-benzthiazinen |
| US3422101A (en) * | 1967-05-05 | 1969-01-14 | Mcneilab Inc | Tetrahydrothienobenzothiazines |
| US4512990A (en) * | 1982-02-18 | 1985-04-23 | Syntex (U.S.A.), Inc. | Benzthiazine analogs as antiinflammatory agents |
-
1982
- 1982-08-04 DE DE19823229122 patent/DE3229122A1/de not_active Withdrawn
-
1983
- 1983-07-19 NO NO832625A patent/NO832625L/no unknown
- 1983-07-22 EP EP83107175A patent/EP0101898A1/de not_active Withdrawn
- 1983-07-25 PT PT77097A patent/PT77097B/pt unknown
- 1983-07-29 AU AU17414/83A patent/AU1741483A/en not_active Abandoned
- 1983-08-01 JP JP58139537A patent/JPS5944370A/ja active Pending
- 1983-08-01 IL IL69388A patent/IL69388A0/xx unknown
- 1983-08-02 GR GR72112A patent/GR79355B/el unknown
- 1983-08-02 KR KR1019830003619A patent/KR840005725A/ko not_active Application Discontinuation
- 1983-08-02 FI FI832784A patent/FI832784A/fi not_active Application Discontinuation
- 1983-08-03 DK DK354583A patent/DK354583A/da not_active Application Discontinuation
- 1983-08-03 ZA ZA835673A patent/ZA835673B/xx unknown
- 1983-08-03 ES ES524713A patent/ES8404607A1/es not_active Expired
- 1983-08-03 HU HU832742A patent/HU189314B/hu unknown
- 1983-08-04 PH PH29350A patent/PH18784A/en unknown
-
1985
- 1985-08-29 US US06/770,895 patent/US4636497A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5944370A (ja) | 1984-03-12 |
| DE3229122A1 (de) | 1984-02-09 |
| GR79355B (pt) | 1984-10-22 |
| FI832784A0 (fi) | 1983-08-02 |
| HU189314B (en) | 1986-06-30 |
| FI832784A (fi) | 1984-02-05 |
| ZA835673B (en) | 1984-04-25 |
| ES524713A0 (es) | 1984-05-01 |
| ES8404607A1 (es) | 1984-05-01 |
| IL69388A0 (en) | 1983-11-30 |
| EP0101898A1 (de) | 1984-03-07 |
| AU1741483A (en) | 1984-02-09 |
| DK354583D0 (da) | 1983-08-03 |
| PT77097A (en) | 1983-08-01 |
| KR840005725A (ko) | 1984-11-16 |
| US4636497A (en) | 1987-01-13 |
| NO832625L (no) | 1984-02-06 |
| PH18784A (en) | 1985-09-25 |
| DK354583A (da) | 1984-02-05 |
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