ZA835577B - Anorexigenic trifluoromethylphenyltetrahydropyridines,a process for their preparation and pharmaceutical compositions containing them - Google Patents

Anorexigenic trifluoromethylphenyltetrahydropyridines,a process for their preparation and pharmaceutical compositions containing them

Info

Publication number
ZA835577B
ZA835577B ZA835577A ZA835577A ZA835577B ZA 835577 B ZA835577 B ZA 835577B ZA 835577 A ZA835577 A ZA 835577A ZA 835577 A ZA835577 A ZA 835577A ZA 835577 B ZA835577 B ZA 835577B
Authority
ZA
South Africa
Prior art keywords
anorexigenic
trifluoromethylphenyltetrahydropyridines
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA835577A
Other languages
English (en)
Inventor
Dino Nisato
Marco Frigerio
Giovanna F Miranda
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA835577B publication Critical patent/ZA835577B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA835577A 1982-08-16 1983-07-29 Anorexigenic trifluoromethylphenyltetrahydropyridines,a process for their preparation and pharmaceutical compositions containing them ZA835577B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8214169A FR2531707A1 (fr) 1982-08-16 1982-08-16 Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques

Publications (1)

Publication Number Publication Date
ZA835577B true ZA835577B (en) 1984-04-25

Family

ID=9276890

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA835577A ZA835577B (en) 1982-08-16 1983-07-29 Anorexigenic trifluoromethylphenyltetrahydropyridines,a process for their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US4521428A (da)
EP (1) EP0101381B1 (da)
JP (1) JPS5984865A (da)
AT (1) ATE16805T1 (da)
AU (1) AU562789B2 (da)
CA (1) CA1245662A (da)
DE (1) DE3361424D1 (da)
DK (1) DK169269B1 (da)
ES (1) ES8500264A1 (da)
FI (1) FI73992C (da)
FR (1) FR2531707A1 (da)
GR (1) GR78690B (da)
IE (1) IE55870B1 (da)
IL (1) IL69348A (da)
NO (1) NO161855C (da)
NZ (1) NZ205269A (da)
PT (1) PT77205B (da)
YU (1) YU44750B (da)
ZA (1) ZA835577B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3438394A1 (de) * 1984-10-19 1986-04-30 Merck Patent Gmbh, 6100 Darmstadt Pyridinderivate
FR2639226B1 (fr) * 1988-11-18 1993-11-05 Sanofi Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs
FR2650505B1 (fr) * 1989-08-07 1994-06-03 Midy Spa Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale
US5266573A (en) * 1989-08-07 1993-11-30 Elf Sanofi Trifluoromethylphenyltetrahydropyridines for the treatment and/or prophylaxis of intestinal motility disorders
US5149817A (en) * 1990-03-05 1992-09-22 Shionogi & Co., Ltd. Teirahydropyridine derivatives
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
FR2662442A1 (fr) * 1990-05-23 1991-11-29 Midy Spa Trifluoromethylphenyltetrahydropyridines n-substituees procede pour leur preparation, intermediaires du procede et compositions pharmaceutiques les contenant.
US5618822A (en) * 1990-05-23 1997-04-08 Sanofi N-substituted trifluoromethylphenyltetrahydropyridines, process for the preparation thereof, intermediates in said process and pharmaceutical compositions containing them
FR2672213B1 (fr) * 1991-02-05 1995-03-10 Sanofi Sa Utilisation de derives 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridiniques comme capteurs de radicaux libres.
FR2690158B1 (fr) * 1992-04-17 1994-07-22 Sanofi Elf Nouveau derive arylpiperidinique, procede pour sa preparation et compositions pharmaceutiques le contenant.
US6489334B2 (en) 1996-12-23 2002-12-03 Sanofi-Synthelabo Method for the crystallization of a tetrahydropyridin derivative and resulting crystalline forms
FR2757543B1 (fr) * 1996-12-23 1999-04-02 Sanofi Sa Procede pour la cristallisation d'un derive de tetrahydropyridine et formes cristallines ainsi obtenues
FR2757510B1 (fr) * 1996-12-23 2000-01-07 Sanofi Sa Forme microparticulaire d'un derive de tetrahydropyridine
FR2757511B1 (fr) * 1996-12-23 2001-05-04 Sanofi Sa Procede pour la preparation d'un derive de tetrahydropyridine
FR2762514B1 (fr) 1997-04-29 1999-10-22 Sanofi Sa Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments pour le traitement des maladies entrainant une demyelinisation
FR2763847B1 (fr) 1997-05-28 2003-06-06 Sanofi Sa Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1
WO2002012191A1 (fr) * 2000-08-08 2002-02-14 Shionogi & Co., Ltd. Derives d'amines cycliques et utilisation
WO2013052732A1 (en) 2011-10-07 2013-04-11 Boral Industries Inc. Inorganic polymer/organic polymer composites and methods of making same
US9752015B2 (en) 2014-08-05 2017-09-05 Boral Ip Holdings (Australia) Pty Limited Filled polymeric composites including short length fibers
US9988512B2 (en) 2015-01-22 2018-06-05 Boral Ip Holdings (Australia) Pty Limited Highly filled polyurethane composites
US10030126B2 (en) 2015-06-05 2018-07-24 Boral Ip Holdings (Australia) Pty Limited Filled polyurethane composites with lightweight fillers
US20170267585A1 (en) 2015-11-12 2017-09-21 Amitabha Kumar Filled polyurethane composites with size-graded fillers

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB948071A (en) * 1959-05-01 1964-01-29 May & Baker Ltd New heterocyclic compounds
FR86403E (fr) * 1959-05-01 1966-02-04 May & Baker Ltd Nouveaux dérivés de la phényl-4 pipéridine et leur préparation
GB984364A (en) * 1961-07-28 1965-02-24 May & Baker Ltd Substituted piperidines and tetrahydropyridines
DE2101997A1 (en) * 1971-01-16 1972-08-03 Farbenfabriken Bayer AG, 509öfLeverkusen 1-benzyl-4-subst-tetrahydropyridines - useful as intermediates for pharmaceuticals
FR2416886A1 (fr) * 1978-02-08 1979-09-07 Roussel Uclaf Nouveaux derives de la 3-phenyl-tetrahydropyridine et leurs sels, procedes de preparation et application a titre de medicaments
FR2501682A1 (fr) * 1981-03-11 1982-09-17 Sanofi Sa Trifluoromethylphenylpyridines a activite anorexigene, un procede de preparation et compositions pharmaceutiques en contenant
FR2501506A1 (fr) * 1981-03-11 1982-09-17 Sanofi Sa Compositions pharmaceutiques a action anorexigene contenant des derives de la tetrahydropyridine

Also Published As

Publication number Publication date
GR78690B (da) 1984-09-27
NO832923L (no) 1984-02-17
IL69348A (en) 1986-09-30
FI73992B (fi) 1987-08-31
JPS5984865A (ja) 1984-05-16
YU170683A (en) 1986-06-30
JPH0557266B2 (da) 1993-08-23
FI832930A0 (fi) 1983-08-15
NZ205269A (en) 1986-06-11
DK169269B1 (da) 1994-09-26
DK371983A (da) 1984-02-17
EP0101381A1 (fr) 1984-02-22
US4521428A (en) 1985-06-04
ES525358A0 (es) 1984-10-01
ES8500264A1 (es) 1984-10-01
YU44750B (en) 1991-02-28
IL69348A0 (en) 1983-11-30
AU1757983A (en) 1984-02-23
NO161855C (no) 1989-10-04
DE3361424D1 (en) 1986-01-16
FR2531707B1 (da) 1985-01-18
IE55870B1 (en) 1991-02-14
NO161855B (no) 1989-06-26
FR2531707A1 (fr) 1984-02-17
FI73992C (fi) 1987-12-10
PT77205B (en) 1986-03-20
DK371983D0 (da) 1983-08-15
ATE16805T1 (de) 1985-12-15
AU562789B2 (en) 1987-06-18
IE831885L (en) 1984-02-16
CA1245662A (en) 1988-11-29
FI832930A (fi) 1984-02-17
PT77205A (en) 1983-09-01
EP0101381B1 (fr) 1985-12-04

Similar Documents

Publication Publication Date Title
ZA835577B (en) Anorexigenic trifluoromethylphenyltetrahydropyridines,a process for their preparation and pharmaceutical compositions containing them
DE3567870D1 (en) Xanthine derivatives, processes for their preparation and pharmaceutical compositions containing them
YU138584A (en) Oligoglukoside derivatives
IE901314L (en) 2- substituted-n,n'-di(trimethoxybenzoyl)piperazines
IL80715A0 (en) Pyridine compounds,process for their preparation and pharmaceutical compositions containing them
ES8403109A1 (es) Un procedimiento para la preparacion de 4-(3-trifluormetilfenil)-1,2,3,6-tetrahidropiridinas.
ES8603825A1 (es) Procedimiento de preparacion de nuevos derivados a-etilben- zol con un grupo piperidinopropanolico sustituido y sus sa- les de adicion acidas y amonicas cuaternarias
SE8405338D0 (sv) (1,3) oxazino (4,3-a) isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them
IL67324A0 (en) New dehydrocardenolide derivatives,process for the preparation thereof and pharmaceutical preparations containing the same
IL70062A (en) Epsilon-butyrolactone derivatives,their preparation and pharmaceutical compositions containing them