ZA834908B - Nouvel diphosphonic acid derivatives and their manufacture and use - Google Patents
Nouvel diphosphonic acid derivatives and their manufacture and useInfo
- Publication number
- ZA834908B ZA834908B ZA834908A ZA834908A ZA834908B ZA 834908 B ZA834908 B ZA 834908B ZA 834908 A ZA834908 A ZA 834908A ZA 834908 A ZA834908 A ZA 834908A ZA 834908 B ZA834908 B ZA 834908B
- Authority
- ZA
- South Africa
- Prior art keywords
- nouvel
- manufacture
- acid derivatives
- diphosphonic acid
- diphosphonic
- Prior art date
Links
- XQRLCLUYWUNEEH-UHFFFAOYSA-N diphosphonic acid Chemical class OP(=O)OP(O)=O XQRLCLUYWUNEEH-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids
- C07F9/3869—Polyphosphonic acids containing carboxylic acid or carboxylic acid derivative substituents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4025—Esters of poly(thio)phosphonic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823225469 DE3225469A1 (de) | 1982-07-05 | 1982-07-05 | Diphosphonsaeure-derivate und diese enthaltende pharmazeutische praeparate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA834908B true ZA834908B (en) | 1984-03-28 |
Family
ID=6167887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA834908A ZA834908B (en) | 1982-07-05 | 1983-07-05 | Nouvel diphosphonic acid derivatives and their manufacture and use |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4645762A (fr) |
| EP (1) | EP0098567A3 (fr) |
| JP (1) | JPS5973593A (fr) |
| AU (1) | AU1656983A (fr) |
| CA (1) | CA1222252A (fr) |
| DE (1) | DE3225469A1 (fr) |
| DK (1) | DK311383A (fr) |
| ES (1) | ES523786A0 (fr) |
| FI (1) | FI832467L (fr) |
| GB (1) | GB2122999A (fr) |
| GR (1) | GR77589B (fr) |
| IL (1) | IL69164A0 (fr) |
| ZA (1) | ZA834908B (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2558837B1 (fr) * | 1984-01-26 | 1986-06-27 | Sanofi Sa | Derives de l'acide methylenediphosphonique, procede d'obtention et medicaments antirhumatismaux les contenant |
| DE3512536A1 (de) * | 1985-04-06 | 1986-10-16 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue diphosphonsaeure-derivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel |
| GB8530603D0 (en) * | 1985-12-12 | 1986-01-22 | Leo Pharm Prod Ltd | Chemical compounds |
| DE3724654A1 (de) * | 1987-07-25 | 1989-02-02 | Henkel Kgaa | Hydroxyacetonitrildiphosphonsaeure, verfahren zu ihrer herstellung und ihre verwendung |
| ATE136870T1 (de) * | 1988-11-01 | 1996-05-15 | Arch Dev Corp | Verfahren zur abtrennung von metallischen ionen mit phosphonsäuren als complexbildner |
| FI89364C (fi) * | 1990-12-20 | 1993-09-27 | Leiras Oy | Foerfarande foer framstaellning av nya, farmakologiskt anvaendbara metylenbisfosfonsyraderivat |
| EP0496520A1 (fr) * | 1991-01-22 | 1992-07-29 | Merck & Co. Inc. | Agents actifs sur les os |
| TW222637B (fr) * | 1991-12-12 | 1994-04-21 | Hoechst Ag | |
| DE4228552A1 (de) * | 1992-08-27 | 1994-03-03 | Boehringer Mannheim Gmbh | Diphosphonsäuren und deren Salze enthaltende Arzneimittel |
| CA2347330C (fr) * | 2001-05-10 | 2002-03-12 | Pharmaceutical Partners Of Canada Inc. | Preparation injectable liquide de pamidronate disodique |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4634186Y1 (fr) * | 1967-12-29 | 1971-11-26 | ||
| US3683080A (en) * | 1970-08-28 | 1972-08-08 | Procter & Gamble | Compositions for inhibiting anomalous deposition and mobilization of calcium phosphate in animal tissue |
| US3813456A (en) * | 1972-01-17 | 1974-05-28 | Gates Rubber Co | Process for preparing amino-substituted phosphonates |
| DE2405254C2 (de) * | 1974-02-04 | 1982-05-27 | Henkel KGaA, 4000 Düsseldorf | Verwendung von 3-Amino-1-Hydroxypropan-1, 1-diphosphonsäure oder ihrer wasserlöslichen Salze bei der Beeinflußung von Calciumstoffwechselstörungen im menschlichen oder tierischen Körper |
| DE2602030C2 (de) * | 1976-01-21 | 1983-12-01 | Henkel KGaA, 4000 Düsseldorf | Diphosphonoalkancarbonsäuren und Verfahren zu deren Herstellung |
| JPS52127682U (fr) * | 1976-03-25 | 1977-09-28 | ||
| SU739076A1 (ru) * | 1976-05-19 | 1980-06-05 | Институт Химической Кинетики И Горения Со Ан Ссср | Способ получени -аминоэтилидендифосфоновых кислот |
| DE2860216D1 (en) * | 1977-06-14 | 1981-01-22 | Hoechst Ag | Derivatives of carboxylic acid that contain phosphorus, process for their preparation and their utilisation |
| DE3016289A1 (de) * | 1980-04-28 | 1981-10-29 | Henkel KGaA, 4000 Düsseldorf | Verfahren zur herstellung von omega -amino-1-hydroxyalkyliden-1,1-bis-phosphonsaeuren |
| IT1194748B (it) * | 1981-02-12 | 1988-09-28 | Gentili Ist Spa | Composizioni farmaceutiche per il trattamento di osteopatie |
-
1982
- 1982-07-05 DE DE19823225469 patent/DE3225469A1/de not_active Withdrawn
-
1983
- 1983-07-01 ES ES523786A patent/ES523786A0/es active Granted
- 1983-07-04 GR GR71850A patent/GR77589B/el unknown
- 1983-07-04 CA CA000431700A patent/CA1222252A/fr not_active Expired
- 1983-07-04 EP EP83106511A patent/EP0098567A3/fr not_active Withdrawn
- 1983-07-05 AU AU16569/83A patent/AU1656983A/en not_active Abandoned
- 1983-07-05 DK DK311383A patent/DK311383A/da not_active Application Discontinuation
- 1983-07-05 JP JP58121154A patent/JPS5973593A/ja active Pending
- 1983-07-05 IL IL69164A patent/IL69164A0/xx unknown
- 1983-07-05 US US06/511,116 patent/US4645762A/en not_active Expired - Fee Related
- 1983-07-05 FI FI832467A patent/FI832467L/fi not_active Application Discontinuation
- 1983-07-05 ZA ZA834908A patent/ZA834908B/xx unknown
- 1983-07-05 GB GB08318157A patent/GB2122999A/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| US4645762A (en) | 1987-02-24 |
| GR77589B (fr) | 1984-09-24 |
| DE3225469A1 (de) | 1984-01-05 |
| GB2122999A (en) | 1984-01-25 |
| ES8403492A1 (es) | 1984-04-01 |
| FI832467A0 (fi) | 1983-07-05 |
| EP0098567A3 (fr) | 1984-02-22 |
| IL69164A0 (en) | 1983-11-30 |
| FI832467L (fi) | 1984-01-06 |
| ES523786A0 (es) | 1984-04-01 |
| DK311383D0 (da) | 1983-07-05 |
| EP0098567A2 (fr) | 1984-01-18 |
| JPS5973593A (ja) | 1984-04-25 |
| CA1222252A (fr) | 1987-05-26 |
| DK311383A (da) | 1984-01-06 |
| AU1656983A (en) | 1984-01-26 |
| GB8318157D0 (en) | 1983-08-03 |
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