ZA833494B - Tetrahydro-benzo e isoindolines - Google Patents

Tetrahydro-benzo e isoindolines

Info

Publication number
ZA833494B
ZA833494B ZA833494A ZA833494A ZA833494B ZA 833494 B ZA833494 B ZA 833494B ZA 833494 A ZA833494 A ZA 833494A ZA 833494 A ZA833494 A ZA 833494A ZA 833494 B ZA833494 B ZA 833494B
Authority
ZA
South Africa
Prior art keywords
carbon atoms
hydrogen
loweralkyl
chem
halo
Prior art date
Application number
ZA833494A
Other languages
English (en)
Inventor
John Francis Debernardis
Daniel Joseph Kerkman
William John Mcclellan
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of ZA833494B publication Critical patent/ZA833494B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
    • C07D209/66—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles with oxygen atoms in positions 1 and 3

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA833494A 1982-06-01 1983-05-16 Tetrahydro-benzo e isoindolines ZA833494B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US38363182A 1982-06-01 1982-06-01

Publications (1)

Publication Number Publication Date
ZA833494B true ZA833494B (en) 1984-02-29

Family

ID=23514004

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA833494A ZA833494B (en) 1982-06-01 1983-05-16 Tetrahydro-benzo e isoindolines

Country Status (10)

Country Link
EP (1) EP0095666B1 (en, 2012)
JP (1) JPS58225064A (en, 2012)
KR (1) KR900001193B1 (en, 2012)
AT (1) ATE40115T1 (en, 2012)
AU (1) AU560459B2 (en, 2012)
CA (1) CA1215376A (en, 2012)
DE (1) DE3378978D1 (en, 2012)
ES (1) ES522875A0 (en, 2012)
NZ (1) NZ204213A (en, 2012)
ZA (1) ZA833494B (en, 2012)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4622405A (en) * 1984-07-25 1986-11-11 Abbott Laboratories 1,2,3,3a,8,8a-hexahydro-indeno[1,2-c]pyrroles useful in the treatment of hypertension
ES2090119T3 (es) * 1988-12-15 1996-10-16 Abbott Lab Agentes selectivos de 5-ht.
GR1001059B (el) * 1988-12-15 1993-04-28 Abbott Lab Μεθοδος παραγωγης εκλεκτικων παραγοντων 5-ητ.
FR2722194B1 (fr) * 1994-07-06 1996-08-23 Adir Nouveaux derives de benzopyrane, leur procede de preparation et les compositions pharmacuetiques qui les contiennent
US5792767A (en) * 1995-01-27 1998-08-11 Abbott Laboratories Bicyclic substituted hexahydrobenz e! isoindole alpha-1 adrenergic antagonists
US5891882A (en) * 1996-12-06 1999-04-06 Abbott Laboratories Benzopyranopyrrole and benzopyranopyridine α-1 adenergic compounds
AU735764B2 (en) * 1996-12-06 2001-07-12 Abbott Laboratories Benzopyranopyrrole and benzopyranopyridine alpha-1 adrenergic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3166570A (en) * 1963-02-15 1965-01-19 American Home Prod Derivatives of benzo[e] isoindoline and their preparation
EP0003757B1 (de) * 1978-02-08 1981-10-14 Ciba-Geigy Ag Tricyclische Imidylderivate und Verfahren zu ihrer Herstellung
US4282240A (en) * 1979-11-23 1981-08-04 Merck & Co., Inc. Amino substituted tetrahydrobenzindoles

Also Published As

Publication number Publication date
AU1445283A (en) 1983-12-08
CA1215376A (en) 1986-12-16
ATE40115T1 (de) 1989-02-15
DE3378978D1 (de) 1989-02-23
AU560459B2 (en) 1987-04-09
ES8503329A1 (es) 1985-02-16
ES522875A0 (es) 1985-02-16
JPS58225064A (ja) 1983-12-27
EP0095666B1 (en) 1989-01-18
KR900001193B1 (ko) 1990-02-28
EP0095666A2 (en) 1983-12-07
KR840005096A (ko) 1984-11-03
NZ204213A (en) 1986-06-11
JPH0443064B2 (en, 2012) 1992-07-15
EP0095666A3 (en) 1985-01-16

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