ZA832903B - 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives - Google Patents

1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives

Info

Publication number
ZA832903B
ZA832903B ZA832903A ZA832903A ZA832903B ZA 832903 B ZA832903 B ZA 832903B ZA 832903 A ZA832903 A ZA 832903A ZA 832903 A ZA832903 A ZA 832903A ZA 832903 B ZA832903 B ZA 832903B
Authority
ZA
South Africa
Prior art keywords
azanaphthyridine
naphthyridine
derivatives
azanaphthyridine derivatives
Prior art date
Application number
ZA832903A
Other languages
English (en)
Inventor
Margaret H Sherlock
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA832903B publication Critical patent/ZA832903B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA832903A 1982-04-26 1983-04-25 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives ZA832903B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/371,623 US4452800A (en) 1982-04-26 1982-04-26 Salts of 3(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridine-2(1H)-one and their use in treating chronic obstructive lung diseases

Publications (1)

Publication Number Publication Date
ZA832903B true ZA832903B (en) 1984-01-25

Family

ID=23464718

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA832903A ZA832903B (en) 1982-04-26 1983-04-25 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives

Country Status (3)

Country Link
US (1) US4452800A (fr)
JP (1) JPS58194887A (fr)
ZA (1) ZA832903B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4628055A (en) * 1982-11-03 1986-12-09 Schering Corporation Method for treating allergic reactions and compositions therefore
US4680298A (en) * 1983-05-31 1987-07-14 Schering Corporation Tricyclic anti-allergy and use as anti-inflammatory agents
US4680297A (en) * 1983-07-14 1987-07-14 Schering Corporation Tricyclic positive inotropic agents
US4666922A (en) * 1985-06-18 1987-05-19 Schering Corporation Method for modulating the immune response
US4684727A (en) * 1985-07-29 1987-08-04 Schering Corporation Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents
US5011860A (en) * 1986-04-11 1991-04-30 Schering Corporation Aryl-substituted naphthyridine and pyridopyrazine derivatives and their use in treating hyperproliferative skin diseases
US4760073A (en) * 1986-04-11 1988-07-26 Schering Corporation Aryl-substituted naphthyridine and pyridopyrazine derivatives, useful as anti-allergic agents
US5037826A (en) * 1986-10-15 1991-08-06 Schering Corporation 1-substituted naphthyridine and pyridopyrazine derivatives
US4740511A (en) * 1987-02-18 1988-04-26 Schering Corporation Method of treating hyperproliferative skin disease
JPH07116187B2 (ja) * 1987-07-22 1995-12-13 シェリング・コーポレーション 二環式化合物、それらを薬剤として使用すること、それらの製法、およびそれらの製造に有用な中間体
US4897487A (en) * 1988-04-06 1990-01-30 Schering Corporation Process for preparing intermediates for pharmaceutically useful bicyclic compounds
US5180823A (en) * 1988-04-06 1993-01-19 Schering Corporation Processes for preparing bicyclic compounds
US5079360A (en) * 1988-04-06 1992-01-07 Schering Corporation Processes for preparing bicyclic compounds and intermediates thereof
US5618842A (en) * 1991-12-31 1997-04-08 Lifegroup S.P.A. N-acyl derivatives of aminoalcohols with polycarboxylic acids able to modulate mast cells in inflammatory processes having neuroimmunogenic origin
CN1224624C (zh) * 1999-12-08 2005-10-26 格勒兰制药株式会社 1,8－二氮杂萘－2(1h)－酮衍生物
US20030130288A1 (en) * 2001-09-17 2003-07-10 Henkel Timothy John Method of treatment
JP4294469B2 (ja) * 2001-06-12 2009-07-15 あすか製薬株式会社 Ｐｄｅｉｖ阻害剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA988523A (en) * 1972-06-16 1976-05-04 Merck Sharp And Dohme (I.A.) Corp. 1,8-naphthyridine compounds
DE2635216A1 (de) * 1975-08-15 1977-03-03 Sandoz Ag 4-hydorxy-3-nitropyrido eckige klammer auf 2,3-b eckige klammer zu pyridin2-one und ihre herstellung
JPS5854152B2 (ja) * 1976-03-25 1983-12-02 久光製薬株式会社 新規なナフチリジン誘導体
US4128649A (en) * 1977-06-29 1978-12-05 Sandoz, Inc. 4-Hydroxy-pyrido[2,3-b]pyridine-2(1H)-one-3-carboxylic acids and esters

Also Published As

Publication number Publication date
JPH0568476B2 (fr) 1993-09-29
US4452800A (en) 1984-06-05
JPS58194887A (ja) 1983-11-12

Similar Documents

Publication Publication Date Title
HK20590A (en) 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives
EP0097960A3 (en) Bis-crown-ether derivatives and their use
ZA832903B (en) 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives
IL61930A0 (en) 25-hydroxy-26,26,26,27,27,27-hexafluoroch-olecalciferol and derivatives thereof
DE3574380D1 (en) 1,8-naphthyridine derivatives
ZA83592B (en) Corynantheine derivatives,processes for their preparation,and their use
ZA868752B (en) 6,7,8,9-tetrahydro-10-methylpyrido(1,2-a)indol-9-amines and derivatives thereof
ZA856431B (en) 1,6-naphthyridine derivatives,process for the preparation and the use thereof
DE3365480D1 (en) Oxacephalosporin derivatives, their preparation and use
ZA845708B (en) Novel 1,8-naphthyridine derivatives,and processes for preparation thereof
GB8301383D0 (en) 3,3-dialkyl-and 3,3-alkylene-indoline derivatives
GB2087390B (en) 5,6,7,8-tetrahydro-1,6-naphthyridine derivatives and their preparation
IL68831A (en) 2,2-dimethyl-3-aryl-cyclo-butanones and their preparation
DE3479657D1 (en) 1-normonyl derivatives, processes and use
GB2119374B (en) 1,2,4-triazol-1-yl-propionitrile derivatives their preparation and use
GB2124628B (en) 6-oxo-tetrahydropyran derivatives and cyanomethyl-azetidinones
AU550950B2 (en) N-phenylpyridinamines and pyrido(1,4)-benzodiazepines
ZW26183A1 (en) Pyridone derivatives
GB2080794B (en) 1,6-naphthyridine derivatives
IL71769A0 (en) 4,4'-alkylenedipiperidine derivatives
ZA844618B (en) Tetrahydropyridazinone derivatives,processes for their preparation and their use
DE3368640D1 (en) 5,2',3',4',4",6"-hexadeoxykanamycin and its 1-n-acylated derivative
ZA832310B (en) 1,3,5-triacrylylhexahydro-s-triazine derivatives
GB2152036B (en) 4,5,6,7-tetrahydrobenzimidazole derivatives
IE820829L (en) Pyrazolopyridine derivatives