ZA826539B - Cephalosporin isoquinolinium betaines - Google Patents

Cephalosporin isoquinolinium betaines

Info

Publication number
ZA826539B
ZA826539B ZA826539A ZA826539A ZA826539B ZA 826539 B ZA826539 B ZA 826539B ZA 826539 A ZA826539 A ZA 826539A ZA 826539 A ZA826539 A ZA 826539A ZA 826539 B ZA826539 B ZA 826539B
Authority
ZA
South Africa
Prior art keywords
isoquinolinium
cephalosporin
betaines
isoquinolinium betaines
cephalosporin isoquinolinium
Prior art date
Application number
ZA826539A
Other languages
English (en)
Inventor
Henry Walker Lunn William
John Kevin Shadle
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA826539B publication Critical patent/ZA826539B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA826539A 1981-09-08 1982-09-07 Cephalosporin isoquinolinium betaines ZA826539B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/300,100 US4396619A (en) 1981-09-08 1981-09-08 Cephalosporin betaines

Publications (1)

Publication Number Publication Date
ZA826539B true ZA826539B (en) 1984-04-25

Family

ID=23157706

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA826539A ZA826539B (en) 1981-09-08 1982-09-07 Cephalosporin isoquinolinium betaines

Country Status (11)

Country Link
US (1) US4396619A (it)
JP (1) JPS5857386A (it)
AU (1) AU8808982A (it)
BE (1) BE894333A (it)
DE (1) DE3233377A1 (it)
FR (1) FR2512448B1 (it)
GB (1) GB2105334B (it)
IL (1) IL66727A0 (it)
IT (1) IT1158049B (it)
NL (1) NL8203481A (it)
ZA (1) ZA826539B (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1582884A (en) * 1977-05-19 1981-01-14 Beecham Group Ltd Clavulanic acid derivatives their preparation and use
ZA804670B (en) * 1979-08-03 1981-07-29 Beecham Group Ltd Derivatives of clavulanic acid, a process for their preparation and their use
EP0053893B1 (en) * 1980-12-09 1985-03-20 Beecham Group Plc Derivatives of clavulanic acid, their preparation and their use
NZ199200A (en) * 1980-12-23 1984-07-31 Beecham Group Ltd Clavulanic acid derivatives and pharmaceutical compositions
DE3207840A1 (de) * 1982-03-04 1983-09-15 Hoechst Ag, 6230 Frankfurt "cephalosporinderivate und verfahren zu ihrer herstellung"
DE3247614A1 (de) * 1982-12-23 1984-07-05 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3316797A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
DE3316798A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
FR2546520B1 (fr) * 1983-05-27 1985-08-30 Sanofi Sa Nouveaux composes antibiotiques derives des cephalosporines
DE3587997D1 (de) * 1984-12-27 1995-04-06 Banyu Pharma Co Ltd Isoindolinderivate.
JPS61186253A (ja) * 1985-02-14 1986-08-19 電気化学工業株式会社 高強度水中モルタル・コンクリ−ト組成物
US4703118A (en) * 1985-04-08 1987-10-27 Eli Lilly And Company Synthesis of 3-iodomethyl cephalosporins
IL78634A0 (en) 1985-04-30 1986-08-31 Lilly Co Eli 7-substituted bicyclic pyrazolidinones
JPS61281057A (ja) * 1985-06-06 1986-12-11 日鐵セメント株式会社 高強度・高耐久性モルタル・コンクリ−ト用組成物
CA1296012C (en) * 1986-03-19 1992-02-18 Susumu Nakagawa 6,7-dihydroxy-isoquinoline derivatives
US4814328A (en) * 1986-03-19 1989-03-21 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, and antibacterial agents
US5019571A (en) * 1988-01-25 1991-05-28 Eli Lilly And Company 1-carbacephalosporin antibiotics
DE3910421A1 (de) * 1989-03-31 1990-10-04 Hoechst Ag Polare cephalosporinderivate und verfahren zu ihrer herstellung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE786271A (fr) * 1971-07-17 1973-01-15 Takeda Chemical Industries Ltd Cephalosporines
US4160830A (en) * 1971-07-17 1979-07-10 Takeda Chemical Industries, Ltd. Cephalosporins
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
JPS609719B2 (ja) * 1977-08-06 1985-03-12 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
FR2410655A1 (fr) * 1977-12-05 1979-06-29 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
GB2105334B (en) 1985-05-01
AU8808982A (en) 1983-03-17
DE3233377A1 (de) 1983-03-24
GB2105334A (en) 1983-03-23
US4396619A (en) 1983-08-02
JPS5857386A (ja) 1983-04-05
IT8223151A0 (it) 1982-09-07
IT1158049B (it) 1987-02-18
NL8203481A (nl) 1983-04-05
FR2512448B1 (fr) 1986-02-21
IL66727A0 (en) 1982-12-31
BE894333A (fr) 1983-03-07
FR2512448A1 (fr) 1983-03-11

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