ZA821534B - Rapid solid phase synthesis of olignucleotides using phosphorus oxychloride activation - Google Patents
Rapid solid phase synthesis of olignucleotides using phosphorus oxychloride activationInfo
- Publication number
- ZA821534B ZA821534B ZA821534A ZA821534A ZA821534B ZA 821534 B ZA821534 B ZA 821534B ZA 821534 A ZA821534 A ZA 821534A ZA 821534 A ZA821534 A ZA 821534A ZA 821534 B ZA821534 B ZA 821534B
- Authority
- ZA
- South Africa
- Prior art keywords
- olignucleotides
- activation
- solid phase
- phase synthesis
- phosphorus oxychloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24223181A | 1981-03-10 | 1981-03-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA821534B true ZA821534B (en) | 1984-04-25 |
Family
ID=22913966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA821534A ZA821534B (en) | 1981-03-10 | 1982-03-09 | Rapid solid phase synthesis of olignucleotides using phosphorus oxychloride activation |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0073826A1 (fr) |
WO (1) | WO1982003079A1 (fr) |
ZA (1) | ZA821534B (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5539097A (en) * | 1983-09-02 | 1996-07-23 | Molecular Biosystems, Inc. | Oligonucleotide polymeric support system |
US4507433A (en) * | 1983-10-07 | 1985-03-26 | The Johns Hopkins University | Preparation of oligodeoxyribonucleoside alkyl or arylphosphonates |
JPS62265299A (ja) * | 1985-12-18 | 1987-11-18 | Senjiyu Seiyaku Kk | α―トコフェロールとウリジンとのリン酸ジエステル,そのハロゲン置換体もしくはこれらの塩およびそれらの製造法 |
US5047524A (en) * | 1988-12-21 | 1991-09-10 | Applied Biosystems, Inc. | Automated system for polynucleotide synthesis and purification |
US5262530A (en) * | 1988-12-21 | 1993-11-16 | Applied Biosystems, Inc. | Automated system for polynucleotide synthesis and purification |
WO1994001446A2 (fr) * | 1992-07-09 | 1994-01-20 | Beckman Instruments, Inc. | Support solide organique derive utilise pour effectuer la synthese d'acides nucleiques |
FR2714061B1 (fr) * | 1993-12-16 | 1996-03-08 | Genset Sa | Procédé de préparation de polynucléotides sur support solide et appareil permettant sa mise en Óoeuvre. |
US6469157B1 (en) | 1993-12-16 | 2002-10-22 | Proligo Llc | Process for preparing polynucleotides on a solid support |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3288780A (en) * | 1962-01-30 | 1966-11-29 | Ajinomoto Kk | Process for preparing 5'-ribonucleotides |
GB1157275A (en) * | 1965-07-27 | 1969-07-02 | Takeda Chemical Industries Ltd | A Method for the Production of 5'-Ribonucleotide |
US3466273A (en) * | 1966-12-16 | 1969-09-09 | Asahi Chemical Ind | Process for producing nucleotide by a selective phosphorylation |
CA1159052A (fr) * | 1980-02-29 | 1983-12-20 | University Patents, Inc. | Methode de preparation d'oligonucleotides |
-
1982
- 1982-03-09 EP EP82901233A patent/EP0073826A1/fr not_active Withdrawn
- 1982-03-09 ZA ZA821534A patent/ZA821534B/xx unknown
- 1982-03-09 WO PCT/US1982/000305 patent/WO1982003079A1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
WO1982003079A1 (fr) | 1982-09-16 |
EP0073826A1 (fr) | 1983-03-16 |
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