ZA812665B - 7-fluoro-dibenzo (b,f) thiepin derivatives - Google Patents

7-fluoro-dibenzo (b,f) thiepin derivatives

Info

Publication number
ZA812665B
ZA812665B ZA00812665A ZA812665A ZA812665B ZA 812665 B ZA812665 B ZA 812665B ZA 00812665 A ZA00812665 A ZA 00812665A ZA 812665 A ZA812665 A ZA 812665A ZA 812665 B ZA812665 B ZA 812665B
Authority
ZA
South Africa
Prior art keywords
dibenzo
fluoro
hydroxy
amino
thiepin
Prior art date
Application number
ZA00812665A
Other languages
English (en)
Inventor
J Rokach
C Rooney
E Cragoe Jr
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA812665B publication Critical patent/ZA812665B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Insulating Materials (AREA)
  • Paints Or Removers (AREA)
ZA00812665A 1980-11-24 1981-04-23 7-fluoro-dibenzo (b,f) thiepin derivatives ZA812665B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20943480A 1980-11-24 1980-11-24

Publications (1)

Publication Number Publication Date
ZA812665B true ZA812665B (en) 1982-04-28

Family

ID=22778742

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00812665A ZA812665B (en) 1980-11-24 1981-04-23 7-fluoro-dibenzo (b,f) thiepin derivatives

Country Status (14)

Country Link
EP (1) EP0052912B1 (xx)
JP (1) JPS5788176A (xx)
AT (1) ATE11670T1 (xx)
CA (1) CA1175846A (xx)
DE (1) DE3168733D1 (xx)
DK (1) DK168881A (xx)
ES (1) ES501935A0 (xx)
FI (1) FI811305L (xx)
GR (1) GR75218B (xx)
IE (1) IE51136B1 (xx)
NO (1) NO811187L (xx)
NZ (1) NZ196805A (xx)
PT (1) PT73000B (xx)
ZA (1) ZA812665B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535171A (en) * 1982-11-18 1985-08-13 Merck Frosst Canada, Inc. Dibenzo[b,f]thiepin-3-carboxaldehydes as prostaglandin antagonists
US4622403A (en) * 1983-10-11 1986-11-11 Merck Frosst Canada, Inc. 6-H dibenz[b,f]thiepin compounds
CA1240699A (en) * 1984-05-14 1988-08-16 Thomas R. Verhoeven Preparation of dibenzo(b,f)thiepin compounds
US4558037A (en) * 1984-06-04 1985-12-10 Merck & Co., Inc. Cardiovascular composition
KR100769084B1 (ko) 2005-02-17 2007-10-22 동우신테크 주식회사 디벤조티에핀 유도체의 제조 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51108082A (en) * 1975-03-15 1976-09-25 Nippon Chemiphar Co 99 karubokishi 10*111 jihidorojibenzo * b*f * chepinjudotainoseiho
US4101667A (en) * 1975-05-30 1978-07-18 Nippon Chemiphar Co., Ltd. Benzo[b,f]thiepin derivatives
GB1487280A (en) * 1975-11-06 1977-09-28 Nippon Chemiphar Co 10,11-dihydrodibenzo-(b,f)-thiepin-1-carboxylic acid derivatives and a process for producing the same
JPS5346990A (en) * 1976-10-06 1978-04-27 Nippon Chemiphar Co Ltd Dibenzo(d,f)thiepin derivatives and their preparation
JPS5346989A (en) * 1976-10-06 1978-04-27 Nippon Chemiphar Co Ltd Novel dibenzo(b,f)thiepin derivatives and their preparation
PT68303A (en) * 1977-07-26 1978-08-01 Merck & Co Inc Process for the preparation of dibenzo/b,f/thiepin
FI801638A (fi) * 1979-06-01 1980-12-02 Merck & Co Inc Prostaglandinantagonister

Also Published As

Publication number Publication date
PT73000B (en) 1983-02-08
ES8306140A1 (es) 1982-08-16
DE3168733D1 (en) 1985-03-21
ES501935A0 (es) 1982-08-16
EP0052912A1 (en) 1982-06-02
IE51136B1 (en) 1986-10-15
ATE11670T1 (de) 1985-02-15
NZ196805A (en) 1983-07-15
DK168881A (da) 1982-05-25
PT73000A (en) 1981-06-01
FI811305L (fi) 1982-05-25
GR75218B (xx) 1984-07-13
IE810798L (en) 1982-05-24
NO811187L (no) 1982-05-25
CA1175846A (en) 1984-10-09
EP0052912B1 (en) 1985-02-06
JPS5788176A (en) 1982-06-01

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