ZA806555B - Amino derivatives of 5-(2-hydroxystyryl)-isoxazole,their preparation and therapeutic formulations containing these compounds - Google Patents
Amino derivatives of 5-(2-hydroxystyryl)-isoxazole,their preparation and therapeutic formulations containing these compoundsInfo
- Publication number
- ZA806555B ZA806555B ZA00806555A ZA806555A ZA806555B ZA 806555 B ZA806555 B ZA 806555B ZA 00806555 A ZA00806555 A ZA 00806555A ZA 806555 A ZA806555 A ZA 806555A ZA 806555 B ZA806555 B ZA 806555B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydroxystyryl
- isoxazole
- compounds
- preparation
- formulations containing
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 150000001412 amines Chemical class 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- MXZROAOUCUVNHX-UHFFFAOYSA-N 2-Aminopropanol Chemical class CCC(N)O MXZROAOUCUVNHX-UHFFFAOYSA-N 0.000 abstract 1
- 206010020852 Hypertonia Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 208000029078 coronary artery disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- -1 their preparation Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
- C07F9/653—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/04—Saturated ethers
- C07C43/12—Saturated ethers containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792943405 DE2943405A1 (de) | 1979-10-26 | 1979-10-26 | Neue aminoderivate des 5-(2-hydroxystyryl)-isoxazols |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA806555B true ZA806555B (en) | 1981-11-25 |
Family
ID=6084497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00806555A ZA806555B (en) | 1979-10-26 | 1980-10-24 | Amino derivatives of 5-(2-hydroxystyryl)-isoxazole,their preparation and therapeutic formulations containing these compounds |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4305951A (ja) |
| EP (1) | EP0027978B1 (ja) |
| JP (1) | JPS5673076A (ja) |
| AT (1) | ATE2145T1 (ja) |
| AU (1) | AU532983B2 (ja) |
| CA (1) | CA1157476A (ja) |
| DE (2) | DE2943405A1 (ja) |
| DK (1) | DK449680A (ja) |
| ES (1) | ES496240A0 (ja) |
| IE (1) | IE50797B1 (ja) |
| IL (1) | IL61274A (ja) |
| NO (1) | NO803176L (ja) |
| ZA (1) | ZA806555B (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2152310T3 (es) * | 1993-03-29 | 2001-02-01 | Basf Ag | Derivados de 1-amino-3-fenoxipropano como moduladores de la resistencia a multiples a farmacos. |
| US6025359A (en) | 1996-06-17 | 2000-02-15 | Eli Lilly And Company | Drug resistance and multidrug resistance modulators |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH451115A (de) | 1964-09-10 | 1968-05-15 | Ciba Geigy | Verfahren zur Herstellung eines neuen Amins |
| CA945172A (en) | 1969-02-21 | 1974-04-09 | Imperial Chemical Industries Limited | Alkanolamine derivatives |
| BE754405A (fr) | 1969-08-05 | 1971-02-04 | Thomae Gmbh Dr K | Nouveaux beta-aryl-2-aminoalcoxystyrenes |
| US3624079A (en) * | 1969-10-20 | 1971-11-30 | Upjohn Co | 5-(phenylstryl)-3methylisoxazoles |
| DE2549962A1 (de) * | 1975-11-07 | 1977-05-18 | Basf Ag | Neue isoxazole und verfahren zu ihrer herstellung |
| DE2624918A1 (de) | 1976-06-03 | 1977-12-15 | Thomae Gmbh Dr K | Arzneimittel mit antiarrhythmischer wirkung |
| DE2818999A1 (de) * | 1978-04-29 | 1979-11-15 | Basf Ag | Aminoderivate von 3-alkyl-5-(2- hydroxystyryl)-isoxazolen |
-
1979
- 1979-10-26 DE DE19792943405 patent/DE2943405A1/de not_active Withdrawn
-
1980
- 1980-10-15 IL IL61274A patent/IL61274A/xx unknown
- 1980-10-16 CA CA000362510A patent/CA1157476A/en not_active Expired
- 1980-10-18 DE DE8080106357T patent/DE3061518D1/de not_active Expired
- 1980-10-18 EP EP80106357A patent/EP0027978B1/de not_active Expired
- 1980-10-18 AT AT80106357T patent/ATE2145T1/de not_active IP Right Cessation
- 1980-10-23 IE IE2191/80A patent/IE50797B1/en unknown
- 1980-10-23 US US06/199,835 patent/US4305951A/en not_active Expired - Lifetime
- 1980-10-24 ZA ZA00806555A patent/ZA806555B/xx unknown
- 1980-10-24 NO NO803176A patent/NO803176L/no unknown
- 1980-10-24 ES ES496240A patent/ES496240A0/es active Granted
- 1980-10-24 DK DK449680A patent/DK449680A/da not_active Application Discontinuation
- 1980-10-24 AU AU63667/80A patent/AU532983B2/en not_active Ceased
- 1980-10-27 JP JP14950780A patent/JPS5673076A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DE2943405A1 (de) | 1981-05-07 |
| NO803176L (no) | 1981-04-27 |
| IL61274A (en) | 1984-04-30 |
| US4305951A (en) | 1981-12-15 |
| EP0027978B1 (de) | 1982-12-29 |
| ES8106895A1 (es) | 1981-09-16 |
| IE50797B1 (en) | 1986-07-23 |
| EP0027978A1 (de) | 1981-05-06 |
| AU6366780A (en) | 1981-04-30 |
| IE802191L (en) | 1981-04-26 |
| CA1157476A (en) | 1983-11-22 |
| ATE2145T1 (de) | 1983-01-15 |
| ES496240A0 (es) | 1981-09-16 |
| JPS5673076A (en) | 1981-06-17 |
| DK449680A (da) | 1981-04-27 |
| IL61274A0 (en) | 1980-12-31 |
| DE3061518D1 (en) | 1983-02-03 |
| AU532983B2 (en) | 1983-10-20 |
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