ZA804709B - Novel derivatives of 3,4,5-trimethoxy cinnamoyl piperazine,the process for preparing the same and their use in therapeutics - Google Patents
Novel derivatives of 3,4,5-trimethoxy cinnamoyl piperazine,the process for preparing the same and their use in therapeuticsInfo
- Publication number
- ZA804709B ZA804709B ZA00804709A ZA804709A ZA804709B ZA 804709 B ZA804709 B ZA 804709B ZA 00804709 A ZA00804709 A ZA 00804709A ZA 804709 A ZA804709 A ZA 804709A ZA 804709 B ZA804709 B ZA 804709B
- Authority
- ZA
- South Africa
- Prior art keywords
- therapeutics
- preparing
- same
- novel derivatives
- trimethoxy cinnamoyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7919990A FR2462432A2 (fr) | 1979-08-03 | 1979-08-03 | Nouveaux derives de la 3,4,5 trimethoxy cinnamoyle piperazine, leur procede de preparation et leur application en therapeutique |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA804709B true ZA804709B (en) | 1981-10-28 |
Family
ID=9228620
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA00804709A ZA804709B (en) | 1979-08-03 | 1980-08-01 | Novel derivatives of 3,4,5-trimethoxy cinnamoyl piperazine,the process for preparing the same and their use in therapeutics |
Country Status (14)
Country | Link |
---|---|
JP (1) | JPS5626885A (da) |
AU (1) | AU6100380A (da) |
BE (1) | BE884602R (da) |
CA (1) | CA1155121A (da) |
CH (1) | CH646694A5 (da) |
DE (1) | DE3028912A1 (da) |
ES (2) | ES8107195A1 (da) |
FR (1) | FR2462432A2 (da) |
GB (1) | GB2057433B (da) |
GR (1) | GR68073B (da) |
LU (1) | LU82677A1 (da) |
NL (1) | NL8004434A (da) |
SE (1) | SE8005300L (da) |
ZA (1) | ZA804709B (da) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2507604A2 (fr) * | 1977-04-19 | 1982-12-17 | Delalande Sa | Nouvelles trimethoxy-3,4,5 cinnamoyle piperazines, leur procede de preparation et leur application en therapeutique |
US4567264A (en) * | 1983-05-18 | 1986-01-28 | Syntex (U.S.A.) Inc. | Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry |
US4558129A (en) * | 1983-05-18 | 1985-12-10 | Syntex (U.S.A.) Inc. | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade |
US4499100A (en) * | 1983-05-18 | 1985-02-12 | Syntex (U.S.A.) Inc. | Benzodioxanyl-hydroxyethyleneamino-piperidinyl acetanilides, ketones, esters and carbamates which effect immunity and calcium entry and β-blockade |
US4997836A (en) * | 1988-11-11 | 1991-03-05 | Takeda Chemical Industries, Ltd. | Trisubstituted piperazine compounds, their production and use |
US6514996B2 (en) | 1995-05-19 | 2003-02-04 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of benzofuran or benzodioxole |
EP0943613A4 (en) * | 1996-11-19 | 2002-07-10 | Kyowa Hakko Kogyo Kk | HETEROCYCLIC COMPOUNDS CONTAINING OXYGEN |
WO2008144933A1 (en) | 2007-05-29 | 2008-12-04 | Université de Montréal | Cinnamoyl inhibitors of transglutaminase |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2387971A1 (fr) * | 1977-04-19 | 1978-11-17 | Delalande Sa | Nouvelles trimethoxy cinnamoyles piperazines, leur procede de preparation et leur application en therapeutique |
-
1979
- 1979-08-03 FR FR7919990A patent/FR2462432A2/fr active Granted
-
1980
- 1980-07-18 CH CH551180A patent/CH646694A5/fr not_active IP Right Cessation
- 1980-07-21 CA CA000356675A patent/CA1155121A/en not_active Expired
- 1980-07-22 SE SE8005300A patent/SE8005300L/xx not_active Application Discontinuation
- 1980-07-28 GR GR62561A patent/GR68073B/el unknown
- 1980-07-30 DE DE19803028912 patent/DE3028912A1/de not_active Ceased
- 1980-08-01 JP JP10632080A patent/JPS5626885A/ja active Granted
- 1980-08-01 BE BE0/201625A patent/BE884602R/fr not_active IP Right Cessation
- 1980-08-01 ES ES493931A patent/ES8107195A1/es not_active Expired
- 1980-08-01 AU AU61003/80A patent/AU6100380A/en not_active Abandoned
- 1980-08-01 LU LU82677A patent/LU82677A1/fr unknown
- 1980-08-01 ZA ZA00804709A patent/ZA804709B/xx unknown
- 1980-08-01 GB GB8025200A patent/GB2057433B/en not_active Expired
- 1980-08-04 NL NL8004434A patent/NL8004434A/nl not_active Application Discontinuation
-
1981
- 1981-02-26 ES ES499814A patent/ES8301944A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2462432A2 (fr) | 1981-02-13 |
SE8005300L (sv) | 1981-02-04 |
BE884602R (fr) | 1981-02-02 |
ES499814A0 (es) | 1982-12-16 |
JPS634827B2 (da) | 1988-02-01 |
GB2057433B (en) | 1983-08-10 |
CH646694A5 (fr) | 1984-12-14 |
ES493931A0 (es) | 1981-10-01 |
LU82677A1 (fr) | 1982-05-10 |
ES8301944A1 (es) | 1982-12-16 |
AU6100380A (en) | 1981-02-05 |
JPS5626885A (en) | 1981-03-16 |
CA1155121A (en) | 1983-10-11 |
ES8107195A1 (es) | 1981-10-01 |
GB2057433A (en) | 1981-04-01 |
DE3028912A1 (de) | 1981-09-24 |
FR2462432B2 (da) | 1983-05-27 |
GR68073B (da) | 1981-10-29 |
NL8004434A (nl) | 1981-02-05 |
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