ZA802389B - New derivative of 1 alpha,25-dihydroxy-cholecalciferol,process for preparing it,its use as a medicament and the pharmaceutical compositions containing it - Google Patents

New derivative of 1 alpha,25-dihydroxy-cholecalciferol,process for preparing it,its use as a medicament and the pharmaceutical compositions containing it

Info

Publication number
ZA802389B
ZA802389B ZA00802389A ZA802389A ZA802389B ZA 802389 B ZA802389 B ZA 802389B ZA 00802389 A ZA00802389 A ZA 00802389A ZA 802389 A ZA802389 A ZA 802389A ZA 802389 B ZA802389 B ZA 802389B
Authority
ZA
South Africa
Prior art keywords
cholecalciferol
dihydroxy
medicament
alpha
preparing
Prior art date
Application number
ZA00802389A
Other languages
English (en)
Inventor
J Taillardat
J Jolly
P Rizzi
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA802389B publication Critical patent/ZA802389B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA00802389A 1979-05-23 1980-04-21 New derivative of 1 alpha,25-dihydroxy-cholecalciferol,process for preparing it,its use as a medicament and the pharmaceutical compositions containing it ZA802389B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7913118A FR2457282A1 (fr) 1979-05-23 1979-05-23 Nouveau derive du 1a,25 dihydroxy cholecalciferol, son procede de preparation et son application comme medicament

Publications (1)

Publication Number Publication Date
ZA802389B true ZA802389B (en) 1981-04-29

Family

ID=9225772

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00802389A ZA802389B (en) 1979-05-23 1980-04-21 New derivative of 1 alpha,25-dihydroxy-cholecalciferol,process for preparing it,its use as a medicament and the pharmaceutical compositions containing it

Country Status (19)

Country Link
US (1) US4435325A (nl)
JP (1) JPS55160758A (nl)
AT (1) AT371434B (nl)
AU (1) AU530140B2 (nl)
BE (1) BE883435A (nl)
CA (1) CA1140155A (nl)
CH (1) CH646146A5 (nl)
DE (1) DE3019885A1 (nl)
ES (1) ES8102092A1 (nl)
FR (1) FR2457282A1 (nl)
GB (1) GB2051818B (nl)
GR (1) GR68548B (nl)
HU (1) HU182137B (nl)
IL (1) IL59857A (nl)
IT (1) IT1145684B (nl)
NL (1) NL8003001A (nl)
PT (1) PT71293B (nl)
SE (1) SE445345B (nl)
ZA (1) ZA802389B (nl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634692A (en) * 1981-08-28 1987-01-06 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxy-24R-fluorocholecalciferol and 1α,25-dihydroxy-24S-fluorocholecalciferol
US4610978A (en) * 1983-03-22 1986-09-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same
USRE33107E (en) * 1983-03-22 1989-11-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same
US4769181A (en) * 1983-11-07 1988-09-06 Wisconsin Alumni Research Foundation 1,25-dihydroxyvitamin D2 compounds
USRE39706E1 (en) * 1993-01-15 2007-06-26 Leo Pharma A/S Crystalline form of a vitamin D analogue

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US3697559A (en) * 1971-02-25 1972-10-10 Wisconsin Alumni Res Found 1,25-dihydroxycholecalciferol
JPS4934980A (nl) * 1972-08-04 1974-03-30
US3901928A (en) * 1973-01-10 1975-08-26 Robert Henry Hesse 1' ,3' -dihydroxy steroid-5-enes method of preparing same and their use for preparing 1' -hydroxy-25-hydrogen vitamin d compounds
US3993675A (en) * 1975-02-24 1976-11-23 Hoffmann-La Roche Inc. Process for the preparation of 1α,25-dihydroxycholecalciferol
JPS51100056A (en) * 1975-02-28 1976-09-03 Chugai Pharmaceutical Co Ltd 1 arufua 255 jihidorokishikorekarushifuerooruno seiho
US4022768A (en) * 1976-02-12 1977-05-10 Wisconsin Alumni Research Foundation Process for preparation of 1α,25-dihydroxycholecalciferol

Also Published As

Publication number Publication date
GR68548B (nl) 1982-01-18
SE8002244L (sv) 1980-11-24
NL8003001A (nl) 1980-11-25
GB2051818A (en) 1981-01-21
FR2457282A1 (fr) 1980-12-19
FR2457282B1 (nl) 1983-10-28
CH646146A5 (fr) 1984-11-15
CA1140155A (fr) 1983-01-25
AU5862780A (en) 1980-11-27
PT71293A (fr) 1980-06-01
IL59857A (en) 1983-12-30
SE445345B (sv) 1986-06-16
IT1145684B (it) 1986-11-05
HU182137B (en) 1983-12-28
GB2051818B (en) 1983-06-29
PT71293B (fr) 1981-09-21
DE3019885C2 (nl) 1990-04-05
IL59857A0 (en) 1980-06-30
IT8048763A0 (it) 1980-05-22
AU530140B2 (en) 1983-07-07
JPS55160758A (en) 1980-12-13
DE3019885A1 (de) 1980-11-27
ES491732A0 (es) 1980-12-16
US4435325A (en) 1984-03-06
BE883435A (fr) 1980-11-24
ATA278780A (de) 1982-11-15
ES8102092A1 (es) 1980-12-16
AT371434B (de) 1983-06-27

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