IT1145684B - Nuovi derivati di 1x25 diidrossi colecalciferolo dotati di attivita' farmacologica e procedimento per la loro preparazione - Google Patents
Nuovi derivati di 1x25 diidrossi colecalciferolo dotati di attivita' farmacologica e procedimento per la loro preparazioneInfo
- Publication number
- IT1145684B IT1145684B IT48763/80A IT4876380A IT1145684B IT 1145684 B IT1145684 B IT 1145684B IT 48763/80 A IT48763/80 A IT 48763/80A IT 4876380 A IT4876380 A IT 4876380A IT 1145684 B IT1145684 B IT 1145684B
- Authority
- IT
- Italy
- Prior art keywords
- colecalciferol
- dihydroxy
- procedure
- preparation
- pharmacological activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Nutrition Science (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7913118A FR2457282A1 (fr) | 1979-05-23 | 1979-05-23 | Nouveau derive du 1a,25 dihydroxy cholecalciferol, son procede de preparation et son application comme medicament |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8048763A0 IT8048763A0 (it) | 1980-05-22 |
| IT1145684B true IT1145684B (it) | 1986-11-05 |
Family
ID=9225772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT48763/80A IT1145684B (it) | 1979-05-23 | 1980-05-22 | Nuovi derivati di 1x25 diidrossi colecalciferolo dotati di attivita' farmacologica e procedimento per la loro preparazione |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4435325A (it) |
| JP (1) | JPS55160758A (it) |
| AT (1) | AT371434B (it) |
| AU (1) | AU530140B2 (it) |
| BE (1) | BE883435A (it) |
| CA (1) | CA1140155A (it) |
| CH (1) | CH646146A5 (it) |
| DE (1) | DE3019885A1 (it) |
| ES (1) | ES8102092A1 (it) |
| FR (1) | FR2457282A1 (it) |
| GB (1) | GB2051818B (it) |
| GR (1) | GR68548B (it) |
| HU (1) | HU182137B (it) |
| IL (1) | IL59857A (it) |
| IT (1) | IT1145684B (it) |
| NL (1) | NL8003001A (it) |
| PT (1) | PT71293B (it) |
| SE (1) | SE445345B (it) |
| ZA (1) | ZA802389B (it) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4634692A (en) * | 1981-08-28 | 1987-01-06 | Hoffmann-La Roche Inc. | Synthesis of 1α,25-dihydroxy-24R-fluorocholecalciferol and 1α,25-dihydroxy-24S-fluorocholecalciferol |
| US4610978A (en) * | 1983-03-22 | 1986-09-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same |
| USRE33107E (en) * | 1983-03-22 | 1989-11-07 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same |
| US4769181A (en) * | 1983-11-07 | 1988-09-06 | Wisconsin Alumni Research Foundation | 1,25-dihydroxyvitamin D2 compounds |
| USRE39706E1 (en) * | 1993-01-15 | 2007-06-26 | Leo Pharma A/S | Crystalline form of a vitamin D analogue |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3833622A (en) * | 1969-03-17 | 1974-09-03 | Upjohn Co | Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds |
| US3697559A (en) * | 1971-02-25 | 1972-10-10 | Wisconsin Alumni Res Found | 1,25-dihydroxycholecalciferol |
| JPS4934980A (it) * | 1972-08-04 | 1974-03-30 | ||
| US3901928A (en) * | 1973-01-10 | 1975-08-26 | Robert Henry Hesse | 1' ,3' -dihydroxy steroid-5-enes method of preparing same and their use for preparing 1' -hydroxy-25-hydrogen vitamin d compounds |
| US3993675A (en) * | 1975-02-24 | 1976-11-23 | Hoffmann-La Roche Inc. | Process for the preparation of 1α,25-dihydroxycholecalciferol |
| JPS51100056A (en) * | 1975-02-28 | 1976-09-03 | Chugai Pharmaceutical Co Ltd | 1 arufua 255 jihidorokishikorekarushifuerooruno seiho |
| US4022768A (en) * | 1976-02-12 | 1977-05-10 | Wisconsin Alumni Research Foundation | Process for preparation of 1α,25-dihydroxycholecalciferol |
-
1979
- 1979-05-23 FR FR7913118A patent/FR2457282A1/fr active Granted
-
1980
- 1980-03-24 SE SE8002244A patent/SE445345B/sv not_active IP Right Cessation
- 1980-04-17 IL IL59857A patent/IL59857A/xx unknown
- 1980-04-21 ZA ZA00802389A patent/ZA802389B/xx unknown
- 1980-05-05 US US06/146,497 patent/US4435325A/en not_active Expired - Lifetime
- 1980-05-20 HU HU801252A patent/HU182137B/hu not_active IP Right Cessation
- 1980-05-21 GR GR62007A patent/GR68548B/el unknown
- 1980-05-21 AU AU58627/80A patent/AU530140B2/en not_active Ceased
- 1980-05-22 GB GB8016893A patent/GB2051818B/en not_active Expired
- 1980-05-22 CA CA000352534A patent/CA1140155A/fr not_active Expired
- 1980-05-22 CH CH402080A patent/CH646146A5/fr not_active IP Right Cessation
- 1980-05-22 PT PT71293A patent/PT71293B/pt not_active IP Right Cessation
- 1980-05-22 BE BE0/200723A patent/BE883435A/fr not_active IP Right Cessation
- 1980-05-22 ES ES491732A patent/ES8102092A1/es not_active Expired
- 1980-05-22 IT IT48763/80A patent/IT1145684B/it active
- 1980-05-23 DE DE19803019885 patent/DE3019885A1/de active Granted
- 1980-05-23 JP JP6798480A patent/JPS55160758A/ja active Pending
- 1980-05-23 NL NL8003001A patent/NL8003001A/nl not_active Application Discontinuation
- 1980-05-23 AT AT0278780A patent/AT371434B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR68548B (it) | 1982-01-18 |
| SE8002244L (sv) | 1980-11-24 |
| NL8003001A (nl) | 1980-11-25 |
| GB2051818A (en) | 1981-01-21 |
| FR2457282A1 (fr) | 1980-12-19 |
| FR2457282B1 (it) | 1983-10-28 |
| CH646146A5 (fr) | 1984-11-15 |
| CA1140155A (fr) | 1983-01-25 |
| AU5862780A (en) | 1980-11-27 |
| PT71293A (fr) | 1980-06-01 |
| IL59857A (en) | 1983-12-30 |
| SE445345B (sv) | 1986-06-16 |
| HU182137B (en) | 1983-12-28 |
| GB2051818B (en) | 1983-06-29 |
| PT71293B (fr) | 1981-09-21 |
| DE3019885C2 (it) | 1990-04-05 |
| IL59857A0 (en) | 1980-06-30 |
| IT8048763A0 (it) | 1980-05-22 |
| AU530140B2 (en) | 1983-07-07 |
| JPS55160758A (en) | 1980-12-13 |
| ZA802389B (en) | 1981-04-29 |
| DE3019885A1 (de) | 1980-11-27 |
| ES491732A0 (es) | 1980-12-16 |
| US4435325A (en) | 1984-03-06 |
| BE883435A (fr) | 1980-11-24 |
| ATA278780A (de) | 1982-11-15 |
| ES8102092A1 (es) | 1980-12-16 |
| AT371434B (de) | 1983-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960419 |