ZA801520B - New peptides and processes for the manufacture thereof - Google Patents
New peptides and processes for the manufacture thereofInfo
- Publication number
- ZA801520B ZA801520B ZA00801520A ZA801520A ZA801520B ZA 801520 B ZA801520 B ZA 801520B ZA 00801520 A ZA00801520 A ZA 00801520A ZA 801520 A ZA801520 A ZA 801520A ZA 801520 B ZA801520 B ZA 801520B
- Authority
- ZA
- South Africa
- Prior art keywords
- somatostatin
- radical
- trp
- antagonistic
- processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/065—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for hydroxy functions, not being part of carboxy functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/16—Somatostatin; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH250679 | 1979-03-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA801520B true ZA801520B (en) | 1981-03-25 |
Family
ID=4235326
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA00801520A ZA801520B (en) | 1979-03-16 | 1980-03-14 | New peptides and processes for the manufacture thereof |
Country Status (17)
Country | Link |
---|---|
US (1) | US4316890A (no) |
EP (1) | EP0017760B1 (no) |
JP (1) | JPS55124748A (no) |
KR (1) | KR830001872A (no) |
AT (1) | ATE3283T1 (no) |
AU (1) | AU5646280A (no) |
CA (1) | CA1140117A (no) |
DD (1) | DD151059A5 (no) |
DE (1) | DE3063028D1 (no) |
ES (1) | ES489565A0 (no) |
FI (1) | FI800795A (no) |
GR (1) | GR67655B (no) |
IL (1) | IL59620A (no) |
NO (1) | NO800743L (no) |
NZ (1) | NZ193129A (no) |
PT (1) | PT70951A (no) |
ZA (1) | ZA801520B (no) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
US4612302A (en) * | 1983-11-14 | 1986-09-16 | Brigham And Women's Hospital | Clinical use of somatostatin analogues |
US5504069A (en) * | 1993-02-11 | 1996-04-02 | Biomeasure, Inc. | Inhibition of trauma-induced tumor growth |
US5952465A (en) * | 1993-04-23 | 1999-09-14 | Virginia Commonwealth University | Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site |
CA2161108A1 (en) * | 1993-04-23 | 1994-11-10 | Herbert J. Evans | Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site |
US5965698A (en) * | 1993-04-23 | 1999-10-12 | Virginia Commonwealth University | Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site |
US5928896A (en) * | 1993-04-23 | 1999-07-27 | Virginia Commonwealth University | Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site |
US6258550B1 (en) | 1993-04-23 | 2001-07-10 | Virginia Commonwealth University | Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site |
US6084066A (en) * | 1993-10-29 | 2000-07-04 | Virginia Commonwealth University | Polypetides that include conformation-constraining groups which flank a protein-protein interaction site |
US5597894A (en) * | 1995-06-05 | 1997-01-28 | The Louisiana State University Medical Center Foundation | Multi-tyrosinated somatostatin analogs |
EP0981364B1 (en) * | 1997-05-13 | 2006-03-01 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Method and compositions for treating hyperlipidemia |
US6004928A (en) * | 1997-05-13 | 1999-12-21 | Biomeasure, Incorporated | Method of treating hyperlipidemia |
PT981363E (pt) | 1997-05-13 | 2003-12-31 | Conseils De Rec Appl Scient S | Somatostatina e agonistas da somatostatina para reduzir o peso corporal |
AU8019898A (en) * | 1997-05-13 | 1998-12-08 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Somatostatin and somatostatin agonists for treating insulin insensitivity and syndrome |
US5968903A (en) * | 1998-05-07 | 1999-10-19 | Biomeasure, Incorporated | Inhibition of H. pylori proliferation |
ATE424414T1 (de) | 2001-06-08 | 2009-03-15 | Sod Conseils Rech Applic | Chimere somatostatin-dopamin-analoga |
EP2161037A3 (en) | 2003-04-22 | 2010-05-26 | Ipsen Pharma | Camptothecin-Somatostatin conjugates |
BRPI0915888E2 (pt) | 2008-06-12 | 2020-09-01 | Syntaxin Ltd | polipetídeo, seu método de ativação, sequência de ácido nucléico codificando o mesmo e seu uso |
EP3473643A1 (en) | 2008-06-12 | 2019-04-24 | Ipsen Bioinnovation Limited | Fusion proteins for use in the treatemnt of cancer |
GB0820970D0 (en) | 2008-11-17 | 2008-12-24 | Syntaxin Ltd | Suppression of cancer |
ES2862125T3 (es) | 2013-06-13 | 2021-10-07 | Antisense Therapeutics Ltd | Terapia combinada para acromegalia |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4020157A (en) * | 1975-07-08 | 1977-04-26 | Ayerst Mckenna And Harrison Ltd. | Shortened analogs of somatostatin |
US4372884A (en) * | 1975-08-06 | 1983-02-08 | The Salk Institute For Biological Studies | Pharmaceutically active peptides |
NL7607987A (nl) * | 1975-08-08 | 1977-02-10 | Merck & Co Inc | Werkwijze voor het bereiden van peptiden. |
US4122077A (en) * | 1976-12-17 | 1978-10-24 | American Home Products Corporation | Somatostatin analogs |
US4098782A (en) * | 1977-03-14 | 1978-07-04 | American Home Products Corporation | (His5)-somatostatin and analogues thereof |
US4115554A (en) * | 1977-08-29 | 1978-09-19 | Merck & Co., Inc. | Somatostatin analogs |
GB2019411B (en) * | 1978-04-24 | 1982-06-16 | American Home Prod | Peptides related to somatostatin |
-
1980
- 1980-03-10 US US06/129,066 patent/US4316890A/en not_active Expired - Lifetime
- 1980-03-13 AT AT80101310T patent/ATE3283T1/de not_active IP Right Cessation
- 1980-03-13 DE DE8080101310T patent/DE3063028D1/de not_active Expired
- 1980-03-13 EP EP80101310A patent/EP0017760B1/de not_active Expired
- 1980-03-13 DD DD80219646A patent/DD151059A5/de unknown
- 1980-03-14 NZ NZ193129A patent/NZ193129A/xx unknown
- 1980-03-14 IL IL59620A patent/IL59620A/xx unknown
- 1980-03-14 PT PT70951A patent/PT70951A/pt unknown
- 1980-03-14 AU AU56462/80A patent/AU5646280A/en not_active Abandoned
- 1980-03-14 NO NO800743A patent/NO800743L/no unknown
- 1980-03-14 CA CA000347728A patent/CA1140117A/en not_active Expired
- 1980-03-14 JP JP3170980A patent/JPS55124748A/ja active Pending
- 1980-03-14 ES ES489565A patent/ES489565A0/es active Granted
- 1980-03-14 FI FI800795A patent/FI800795A/fi not_active Application Discontinuation
- 1980-03-14 GR GR61450A patent/GR67655B/el unknown
- 1980-03-14 ZA ZA00801520A patent/ZA801520B/xx unknown
- 1980-03-15 KR KR1019800001097A patent/KR830001872A/ko unknown
Also Published As
Publication number | Publication date |
---|---|
PT70951A (en) | 1980-04-01 |
ATE3283T1 (de) | 1983-05-15 |
NO800743L (no) | 1980-09-17 |
IL59620A (en) | 1983-07-31 |
AU5646280A (en) | 1980-09-18 |
JPS55124748A (en) | 1980-09-26 |
EP0017760A1 (de) | 1980-10-29 |
ES8103028A1 (es) | 1981-02-16 |
CA1140117A (en) | 1983-01-25 |
FI800795A (fi) | 1980-09-17 |
US4316890A (en) | 1982-02-23 |
EP0017760B1 (de) | 1983-05-11 |
ES489565A0 (es) | 1981-02-16 |
IL59620A0 (en) | 1980-06-30 |
DE3063028D1 (en) | 1983-06-16 |
DD151059A5 (de) | 1981-09-30 |
GR67655B (no) | 1981-09-02 |
KR830001872A (ko) | 1983-05-19 |
NZ193129A (en) | 1982-06-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA801520B (en) | New peptides and processes for the manufacture thereof | |
IE801126L (en) | 1,2,4-triazine derivatives | |
ES477695A1 (es) | Un procedimiento para preparar derivados de deshidrociclici-minoacidos. | |
JPS5564587A (en) | Pyrimidoo*6*11a**isoquinolinee44one compound and its manufacture | |
DE3880396D1 (de) | Zur behandlung von neurodegenerativen erkrankungen verwendbare kynurensaeurederivate. | |
DE3667059D1 (en) | Benzodipyrroles, processes for their preparation and pharmaceutical compositions containing these compounds | |
ES461987A3 (es) | Procedimiento para la fabricacion de nuevos gona-4,9 (10) dienos. | |
NZ217007A (en) | Peptide derivative which inhibits proteases, preparation and pharmaceutical composition | |
FR2358384A1 (fr) | Peptides psychopharmacologiquement actifs et derives de ces peptides | |
ES8605769A1 (es) | Un procedimiento para la preparacion de un peptido | |
NO164474C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive heksahydropyrrolo(2,1-a)isokinolin-derivater. | |
ATE3146T1 (de) | Neue 1-aryloxy-3-alkylamino-2-propanole und verfahren zu ihrer herstellung. | |
GB2021588A (en) | Bibenzyl Derivatives, the Preparation thereof and Pharmaceutical Compositions Containing them | |
DE3663947D1 (en) | New indole derivatives, the production and uses thereof | |
SE8604838L (sv) | Farmaceutiska kompositioner | |
ES528460A0 (es) | Procedimiento de preparacion de nuevos deridados de alfa-etibenzol con un grupo amino propanolico sustituido y sus sales de adicion acidas y amonicas cuaternarias. | |
ES484086A1 (es) | Procedimiento para la preparacion de compuestos de isopropi-lamina |