ZA794864B - Substituted bis-benzimidazolyl compounds,process for their manufacture and their use in treating protozoal or virus diseases - Google Patents

Substituted bis-benzimidazolyl compounds,process for their manufacture and their use in treating protozoal or virus diseases

Info

Publication number
ZA794864B
ZA794864B ZA00794864A ZA794864A ZA794864B ZA 794864 B ZA794864 B ZA 794864B ZA 00794864 A ZA00794864 A ZA 00794864A ZA 794864 A ZA794864 A ZA 794864A ZA 794864 B ZA794864 B ZA 794864B
Authority
ZA
South Africa
Prior art keywords
atoms
formula
denotes
see diagramm
alkyl
Prior art date
Application number
ZA00794864A
Other languages
English (en)
Inventor
M Roesner
W Raether
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA794864B publication Critical patent/ZA794864B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/195—Radicals derived from nitrogen analogues of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00794864A 1978-09-14 1979-09-13 Substituted bis-benzimidazolyl compounds,process for their manufacture and their use in treating protozoal or virus diseases ZA794864B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782839989 DE2839989A1 (de) 1978-09-14 1978-09-14 Substituierte bisbenzimidazolylverbindungen, ihre herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
ZA794864B true ZA794864B (en) 1980-08-27

Family

ID=6049430

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00794864A ZA794864B (en) 1978-09-14 1979-09-13 Substituted bis-benzimidazolyl compounds,process for their manufacture and their use in treating protozoal or virus diseases

Country Status (8)

Country Link
EP (1) EP0009163B1 (es)
JP (1) JPS5540689A (es)
AT (1) ATE1285T1 (es)
AU (1) AU5082779A (es)
DE (2) DE2839989A1 (es)
ES (2) ES483994A1 (es)
IL (1) IL58237A0 (es)
ZA (1) ZA794864B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5667975A (en) * 1994-05-06 1997-09-16 The University Of North Carolina Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans
US5643935A (en) * 1995-06-07 1997-07-01 The University Of North Carolina At Chapel Hill Method of combatting infectious diseases using dicationic bis-benzimidazoles
US5935982A (en) * 1997-02-28 1999-08-10 The University Of North Carolina At Chapel Hill Methods of treating retroviral infection and compounds useful therefor
WO1999026932A1 (en) * 1997-11-26 1999-06-03 Axys Pharmaceuticals, Inc. By amidino group substituted heterocyclic derivatives and their use as anticoagulants
WO1999026933A1 (en) * 1997-11-26 1999-06-03 Axys Pharmaceuticals, Inc. Substituted amidinoaryl derivatives and their use as anticoagulants
JP2007521237A (ja) * 2003-09-05 2007-08-02 ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 微生物感染症処置用の新規アミジン化合物
CN101287711A (zh) * 2005-08-23 2008-10-15 宇部兴产株式会社 1-取代-5-酰基咪唑化合物的制备方法
US10961202B2 (en) 2017-11-17 2021-03-30 The Scripps Research Institute Bis-benzimidazole compounds and methods of using the same
CN109651370A (zh) * 2018-12-17 2019-04-19 桂林理工大学 一种嘌呤类衍生物自由基前体分子及其制备方法
CN109369612A (zh) * 2018-12-17 2019-02-22 桂林理工大学 一种结构对称的芳基自由基前体分子及其制备方法
USD976707S1 (en) * 2020-09-30 2023-01-31 Guangdong Industry Polytechnic Bottle

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL268089A (es) * 1960-08-11
DE1645944A1 (de) * 1965-12-06 1971-05-13 Dynachim Sarl Fungicide
DE2711362A1 (de) * 1977-03-16 1978-09-21 Hoechst Ag Substituierte bisbenzimidazolylthiophenverbindungen, ihre herstellung und verwendung

Also Published As

Publication number Publication date
EP0009163A2 (de) 1980-04-02
EP0009163B1 (de) 1982-06-30
ES483990A1 (es) 1980-05-16
IL58237A0 (en) 1979-12-30
ATE1285T1 (de) 1982-07-15
DE2963244D1 (en) 1982-08-19
JPS5540689A (en) 1980-03-22
DE2839989A1 (de) 1980-04-03
AU5082779A (en) 1980-03-20
EP0009163A3 (en) 1980-04-16
ES483994A1 (es) 1980-05-16

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