ZA79253B - Tetrahydroisoquinoline derivatives - Google Patents

Tetrahydroisoquinoline derivatives

Info

Publication number
ZA79253B
ZA79253B ZA79253A ZA79253A ZA79253B ZA 79253 B ZA79253 B ZA 79253B ZA 79253 A ZA79253 A ZA 79253A ZA 79253 A ZA79253 A ZA 79253A ZA 79253 B ZA79253 B ZA 79253B
Authority
ZA
South Africa
Prior art keywords
tetrahydroisoquinoline derivatives
tetrahydroisoquinoline
derivatives
Prior art date
Application number
ZA79253A
Other languages
English (en)
Inventor
J Savarese
S Ginsburg
R Kitz
Original Assignee
Massachusetts Gen Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Gen Hospital filed Critical Massachusetts Gen Hospital
Publication of ZA79253B publication Critical patent/ZA79253B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/10—Quaternary compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA79253A 1978-07-21 1979-01-22 Tetrahydroisoquinoline derivatives ZA79253B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US92679478A 1978-07-21 1978-07-21

Publications (1)

Publication Number Publication Date
ZA79253B true ZA79253B (en) 1980-06-25

Family

ID=25453730

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA79253A ZA79253B (en) 1978-07-21 1979-01-22 Tetrahydroisoquinoline derivatives

Country Status (14)

Country Link
EP (1) EP0010119A1 (es)
JP (1) JPS5517367A (es)
AU (1) AU522421B2 (es)
CA (1) CA1125287A (es)
DD (1) DD142547A5 (es)
DK (1) DK34979A (es)
ES (1) ES477257A1 (es)
FI (1) FI790214A (es)
IE (1) IE790108L (es)
IL (1) IL56487A (es)
IT (1) IT1202871B (es)
MC (1) MC1240A1 (es)
PL (1) PL121468B1 (es)
ZA (1) ZA79253B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8418303D0 (en) * 1984-07-18 1984-08-22 Wellcome Found Compounds
BG41897A1 (en) * 1985-07-19 1987-09-15 Ivanov Dichlormethylate of n, n'- 4, 10- dioxa- 3, 11- bis- tetrahydropapaverine and method for its preparation
US5240939A (en) * 1991-10-31 1993-08-31 Anaquest, Inc. Nitrogen bridge tetrahydroisoquinolines
CN103880744A (zh) * 2012-12-21 2014-06-25 常州工程职业技术学院 一种5’-甲氧基劳丹素的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2662083A (en) * 1950-10-24 1953-12-08 Allen & Hanburys Ltd Heterocyclic polymethylene-bisquaternary ammonium salts and process for preparing same
GB863717A (en) * 1958-07-03 1961-03-22 Allen & Hanburys Ltd Tetrahydropapaverine derivatives and their preparation
GB1125619A (en) * 1965-11-15 1968-08-28 Wellcome Found Derivatives of bis-isoquinolines
AU506657B2 (en) * 1975-12-10 1980-01-17 Wellcome Foundation Limited, The Isoquinoline derivatives
IL55254A (en) * 1977-08-01 1983-03-31 Massachusetts Gen Hospital Bis-isoquinolinium compounds,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JPS5517367A (en) 1980-02-06
IT1202871B (it) 1989-02-15
DK34979A (da) 1980-01-22
MC1240A1 (fr) 1979-10-26
PL121468B1 (en) 1982-05-31
IE790108L (en) 1980-01-21
EP0010119A1 (en) 1980-04-30
DD142547A5 (de) 1980-07-02
PL213098A1 (es) 1980-03-24
ES477257A1 (es) 1979-08-01
FI790214A (fi) 1980-01-22
AU4368879A (en) 1980-01-24
AU522421B2 (en) 1982-06-03
IL56487A0 (en) 1979-03-12
IT7919694A0 (it) 1979-01-29
CA1125287A (en) 1982-06-08
IL56487A (en) 1983-05-15

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