ZA782023B - Derivatives of antibiotic substance milbemycin and processes therefor - Google Patents

Derivatives of antibiotic substance milbemycin and processes therefor

Info

Publication number
ZA782023B
ZA782023B ZA00782023A ZA782023A ZA782023B ZA 782023 B ZA782023 B ZA 782023B ZA 00782023 A ZA00782023 A ZA 00782023A ZA 782023 A ZA782023 A ZA 782023A ZA 782023 B ZA782023 B ZA 782023B
Authority
ZA
South Africa
Prior art keywords
milbemycin
derivatives
antibiotic substance
processes therefor
therefor
Prior art date
Application number
ZA00782023A
Other languages
English (en)
Inventor
M Fisher
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ZA782023B publication Critical patent/ZA782023B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ZA00782023A 1977-04-11 1978-04-10 Derivatives of antibiotic substance milbemycin and processes therefor ZA782023B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/786,172 US4093629A (en) 1977-04-11 1977-04-11 Derivatives of antibiotic substance milbemycin and processes therefor

Publications (1)

Publication Number Publication Date
ZA782023B true ZA782023B (en) 1979-07-25

Family

ID=25137800

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00782023A ZA782023B (en) 1977-04-11 1978-04-10 Derivatives of antibiotic substance milbemycin and processes therefor

Country Status (7)

Country Link
US (1) US4093629A (https=)
JP (1) JPS53130695A (https=)
AU (1) AU516707B2 (https=)
FR (1) FR2387232A1 (https=)
GB (1) GB1576185A (https=)
NZ (1) NZ186852A (https=)
ZA (1) ZA782023B (https=)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4206205A (en) * 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
IL56149A (en) * 1977-12-19 1989-09-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds,their preparation and method for the treatment of parasitic infections in animals therewith
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds
JPS5632481A (en) * 1979-08-23 1981-04-01 Sankyo Co Ltd Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent
US4389397A (en) * 1980-08-04 1983-06-21 Merck & Co., Inc. Solubilization of ivermectin in water
US4285963A (en) * 1980-08-07 1981-08-25 Merck & Co., Inc. Novel derivatives of C-076 compounds
US4378353A (en) * 1981-02-17 1983-03-29 Merck & Co., Inc. Novel C-076 compounds
US4408059A (en) * 1981-12-04 1983-10-04 University Patents, Inc. Spiroketals useful as intermediates in the synthesis of milbemycin and avermectin macrolides
JPS59108785A (ja) * 1982-11-25 1984-06-23 Sankyo Co Ltd ミルベマイシン類の５−オキシム誘導体
US4469682A (en) * 1983-01-28 1984-09-04 Merck & Co., Inc. Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
EP0180539A1 (de) * 1984-09-18 1986-05-07 Ciba-Geigy Ag 13-Halo- und 13-Hydroximilbemycine
AU574852B2 (en) * 1984-10-26 1988-07-14 Sankyo Company Limited 13 - acyloxy - 5 - ketomilbemycin derivatives and preparation of 13 - hydroxy - 5 - ketomilbemycin derivatives
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
FI860233L (fi) * 1985-01-22 1986-07-23 Ciba Geigy Ag 13 -alkyl-milbemycinderivat foer bekaempning av parasiter hos djur och vaexter.
US4587247A (en) * 1985-02-25 1986-05-06 Merck & Co., Inc. Substituted and unsubstituted 13-(alkoxy)methoxy derivatives of the avermectin aglycones, compositions and use
US4666937A (en) * 1985-03-04 1987-05-19 Merck & Co., Inc. Avermectin bioconversion products
JPS6289685A (ja) * 1985-05-31 1987-04-24 Sankyo Co Ltd １３−ハロゲンミルベマイシン誘導体
US4812582A (en) * 1985-07-22 1989-03-14 The Upjohn Company Process for preparing aldol intermediates
US4814347A (en) * 1985-07-22 1989-03-21 The Upjohn Company Anthelmintic spiroketals and method of use
US4680419A (en) * 1985-07-22 1987-07-14 The Upjohn Company Spiroketals and process for preparing same
US4686297A (en) * 1985-07-22 1987-08-11 The Upjohn Company Anthelmintic spiroketals useful for killing parasitic worms
US4820758A (en) * 1985-07-22 1989-04-11 The Upjohn Company Novel [5.5]-spiroketals
DE3785936T2 (de) * 1986-03-25 1993-08-26 Sankyo Co Makrolid-derivate, ihre herstellung und ihre verwendung.
ZA872140B (en) * 1986-03-25 1988-11-30 Sankyo Co Microlide compounds,their preparation and their use
EP0252879B1 (de) * 1986-07-02 1992-05-06 Ciba-Geigy Ag Pestizide
EP0254583B1 (en) * 1986-07-24 1994-09-07 Beecham Group Plc Parasiticidal milbemycin derivatives, a process for their production, and compositions containing the same
US4897416A (en) * 1987-02-18 1990-01-30 Ciba-Geigy Corporation Insecticides and parasiticides
EP0285561A3 (de) * 1987-03-27 1989-10-25 Ciba-Geigy Ag Parasitizide und insektizide Milbemycin-Derivate
EP0325462A3 (en) * 1988-01-22 1989-11-02 Beecham Group Plc Anthelmintic milbemycin derivatives
US5008250A (en) * 1988-05-25 1991-04-16 Merck & Co., Inc. Avermectins with a cleaved furan ring and an 8a hydroxy group
WO1997046204A2 (en) 1996-06-05 1997-12-11 Ashmont Holdings Limited Injectable compositions
AU9785698A (en) 1997-10-02 1999-04-27 Microcide Pharmaceuticals, Inc. Fungal efflux pump inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4914624A (https=) * 1972-06-08 1974-02-08
US3984564A (en) * 1972-06-08 1976-10-05 Sankyo Company Limited Antibiotic substances B-41, their production and their use as insecticides and acaricides
US3950360A (en) * 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis

Also Published As

Publication number Publication date
AU3476178A (en) 1979-10-11
AU516707B2 (en) 1981-06-18
GB1576185A (en) 1980-10-01
FR2387232A1 (fr) 1978-11-10
US4093629A (en) 1978-06-06
JPS53130695A (en) 1978-11-14
FR2387232B1 (https=) 1982-04-09
NZ186852A (en) 1984-09-28

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